6PDVA

Cu-carbonic anhydrase ii, a nitrite reductase
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 22-257 236 1-21, 258-260 21 3 knot
Chain Sequence
SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 7x +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 26-257 232 1-25, 258-260 25 3 knot
Fingerprint Knot forming loop Loop type
K +31 Ser2 <->
Bridging ionCu302
<-> His4 ...
Chain closureLys261 <-> Ser2
probabilistic
K +31 Ser2 ... His94 <->
Bridging ionCu301
<-> His96 ...
Chain closureLys261 <-> Ser2
probabilistic
K +31 Ser2 ... His96 <->
Bridging ionCu301
<-> His119 ...
Chain closureLys261 <-> Ser2
probabilistic
K +31 Ser2 ... His94 <->
Bridging ionCu301
<-> His119 ...
Chain closureLys261 <-> Ser2
probabilistic
K +31 Ser2 <->
Bridging ionCu302
<-> His4 ... His94 <->
Bridging ionCu301
<-> His96 ...
Chain closureLys261 <-> Ser2
probabilistic
K +31 Ser2 <->
Bridging ionCu302
<-> His4 ... His96 <->
Bridging ionCu301
<-> His119 ...
Chain closureLys261 <-> Ser2
probabilistic
K +31 Ser2 <->
Bridging ionCu302
<-> His4 ... His94 <->
Bridging ionCu301
<-> His119 ...
Chain closureLys261 <-> Ser2
probabilistic
Chain Sequence
SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 28-257 230 1-27, 258-259 27 2 knot
view details
2.1 26-253 228 1-25 259-259 254-258 25 1 slipknot
sequence length 259
structure length 259
publication title Structure and mechanism of copper-carbonic anhydrase II: a nitrite reductase.
pubmed doi rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
total genus Genus: 75
ec nomenclature ec 4.2.1.1: Alcohol dehydrogenase.
pdb deposition date 2019-06-19
KnotProt deposition date 2020-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00194 Carb_anhydrase Eukaryotic-type carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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