6F5UA

Crystal structure of ebolavirus glycoprotein in complex with bepridil
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 76-140 65 1-75 145-288 141-144 75 144 slipknot
Chain Sequence
SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQA---------------------SGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTWAFWELSFTVVXXXXXXX
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 78-138 61 1-77 147-250 139-146 77 104 slipknot
view details
1.1 82-139 58 1-77, 143-250 78-81, 140-142 77 108 slipknot
view details
1.1 82-142 61 1-77, 145-250 78-81, 143-144 77 106 slipknot
view details
1.1 82-144 63 1-77, 146-250 78-81, 145-145 77 105 slipknot
sequence length 288
structure length 250
publication title Target identification and mode of action of four chemically divergent drugs against Ebola virus infection.
pubmed doi rcsb
molecule tags Viral protein
molecule keywords Envelope glycoprotein,Envelope glycoprotein,GP1
source organism Zaire ebolavirus (strain mayinga-76)
missing residues 159-179, 254-256, 262-274, 281
total genus Genus: 59
ec nomenclature
pdb deposition date 2017-12-03
KnotProt deposition date 2018-01-03
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling