6FHTA

Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in its dark adapted pr form
Knot K 41 41
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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41 38-276 239 1-37, 277-735 37 459 knot
Chain Sequence
GAMARDPLPFFPPLYLGGPEITTENCEREPIHIPGSIQPHGALLTADGHSGEVLQMSLNAATFLGQEPTVLRGQTLAALLPEQWPALQAALPPGCPDALQYRATLDWPAAGHLSLTVHRVGELLILEFEPTEAWDSTGPHALRNAMFALESAPNLRALAEVATQTVRELTGFDRVMLYKFAPDATGEVIAEARREGLHAFLGHRFPASDIPAQARALYTRHLLRLTADTRAAAVPLDPVLNPQTNAPTPLGGAVLRATSPMHMQYLRNMGVGSSLSVSVVVGGQLWGLIACHHQTPYVLPPDLRTTLEYLGRLLSLQVQVKEAADVAAFRQSLREHHARVALAAAHSLSPHDTLSDPALDLLGLMRAGGLILRFEGRWQTLGEVPPAPAVDALLAWLETQPGALVQTDALGQLWPA-----PSAAGLLAISVGEGWSECLVWLRPELRLEVAWGGATPDQAKDDLGPRHSFDTYLEEKRGYAEPWHPGEIEEAQDLRDTLTGALGERLSVIRVRNTFGRYLTDQVVATLLENPEGLKMGGDRRPITILTSDLRGFTSTSEGLNPEEVVKVLNIYFGKMADVITHHGGTIDKFMGDGILVLFGAPTSQQDDALRAVACGVEMQLALREVNQQVTGLGLQPLEMGIGINTGEVVVGNIGSEKRTKYGVVGAQVNLTYRIESYTTGGQIFISSTTLEAAGDRVHVNGNRTVQPKGVKDPVVIWDVAGVGEPYNLSLAV
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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4.1 36-467 432 1-35, 468-730 35 263 knot
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3.2m 34-270 237 1-33 281-730 271-280 33 450 slipknot
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4.1 13-280 268 1-12 287-730 281-286 12 444 slipknot
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4.1 34-282 249 1-33 292-730 283-291 33 439 slipknot
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4.1 34-291 258 1-33 294-730 292-293 33 437 slipknot
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3.2m 35-295 261 1-34 319-730 296-318 34 412 slipknot
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4.1 36-312 277 1-35 468-730 313-467 35 263 slipknot
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3.2m 18-280 263 1-12, 283-730 13-17, 281-282 12 448 slipknot
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3.2m 26-280 255 1-17, 283-730 18-25, 281-282 17 448 slipknot
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3.2 39-317 279 1-35, 406-730 36-38, 318-405 35 325 slipknot
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3.2 39-405 367 1-35, 719-730 36-38, 406-718 35 12 slipknot
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4.1 39-718 680 719-730 1-35 36-38 35 11 slipknot
missing residues 417-421
publication title Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications
rcsb
structure length 730
molecule tags Lyase
source organism Deinococcus radiodurans
sequence length 735
total genus Genus: 218
molecule keywords Bacteriophytochrome,Adenylate cyclase
ec nomenclature
pdb deposition date 2018-01-15
KnotProt deposition date 2018-04-19
Image from the rcsb pdb (www.rcsb.org)
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