6G9BA

Crystal structure of ebolavirus glycoprotein in complex with imipramine
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 73-141 69 1-1, 145-447 2-72, 142-144 1 303 slipknot
Chain Sequence
RSIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQA---------------------SGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTWAFWETLSFTVVSXXXXXXX
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 78-139 62 1-77 147-253 140-146 77 107 slipknot
view details
1.1 83-140 58 1-77, 146-253 78-82, 141-145 77 108 slipknot
sequence length 289
structure length 253
publication title Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
pubmed doi rcsb
molecule tags Viral protein
molecule keywords Envelope glycoprotein,Envelope glycoprotein
source organism Zaire ebolavirus (strain mayinga-76)
missing residues 160-180, 255-257, 264-275
total genus Genus: 57
ec nomenclature
pdb deposition date 2018-04-10
KnotProt deposition date 2018-09-30
Image from the rcsb pdb (www.rcsb.org)
6F6NA 6F6SA 6G9IA
similar chains in the KnotProt database (40% sequence similarity)
5JQ3A 5JQ7A 5JQBA 6F6IA 6G95A 6HROA
similar chains in the pdb database (40% sequence similarity)

 
#similar chains in the KnotProt database (40% sequence similarity)
6F6N A; 6F6S A; 6G9I A; 
#similar chains, but unknotted

#similar chains in the pdb database (40% sequence similarity)
5JQ3 A; 5JQ7 A; 5JQB A; 6F6I A; 6G95 A; 6HRO A; 

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