6KKTA

Human kcc1 structure determined in kcl and lipid nanodisc
Slipknot S 41 +31 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 30-324 295 1-19, 537-537 20-29, 325-536 19 1 slipknot
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41 13-367 355 1-12 403-537 368-402 12 135 slipknot
Chain Sequence
PSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYI
publication title Cryo-EM structures of the human cation-chloride cotransporter KCC1.
doi rcsb
structure length 537
molecule tags Transport protein
source organism Homo sapiens
sequence length 537
molecule keywords Solute carrier family 12 member 4
ec nomenclature
pdb deposition date 2019-07-27
KnotProt deposition date 2019-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00324 AA_permease Amino acid permease
Image from the rcsb pdb (www.rcsb.org)
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