6N4QE

Cryoem structure of nav1.7 vsd2 (actived state) in complex with the gating modifier toxin protx2
Cysteine knot
Loop Piercing
view details
2-c-9-b-21-c-16 15-b-25
Chain Sequence
YCQKWMWTCDSERKCCEGMVCRLWCKKKLW
sequence length 30
structure length 30
publication title Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
pubmed doi rcsb
molecule tags Membrane protein
molecule keywords Nav1.7 VSD2-NavAb chimera
source organism Arcobacter butzleri (strain rm4018)
ec nomenclature
pdb deposition date 2018-11-20
Image from the rcsb pdb (www.rcsb.org)
1LUPA 1V7FA 5O0UA 5TCZA 6MK4A 6N4IE 6N4QE 6N4RE 6CGWA
similar chains in the KnotProt database (40% sequence similarity)
None
similar chains in the pdb database (40% sequence similarity)

 
#similar chains in the KnotProt database (40% sequence similarity)
1LUP A; 1V7F A; 5O0U A; 5TCZ A; 6MK4 A; 6N4I E; 6N4Q E; 6N4R E; 
#similar chains, but unknotted
6CGW A; 
#similar chains in the pdb database (40% sequence similarity)


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