6QX9BP

Structure of a human fully-assembled precatalytic spliceosome (pre-b complex).
Knot K -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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-31 19-67 49 1-18, 68-100 18 33 knot
Chain Sequence
AKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICGGPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1m 19-85 67 1-18, 86-100 18 15 knot
view details
3.1m 18-69 52 1-17 86-100 70-85 17 15 slipknot
sequence length 100
structure length 100
publication title Mechanism of 5' splice site transfer for human spliceosome activation.
pubmed doi rcsb
molecule tags Splicing
molecule keywords U1 snRNA
source organism Homo sapiens
total genus Genus: 11
ec nomenclature
pdb deposition date 2019-03-07
KnotProt deposition date 2019-04-25
Image from the rcsb pdb (www.rcsb.org)
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