6TL2A

Crystal structure of eremococcus coleocola manganese transporter in complex with an aromatic bis-isothiourea substituted compound
Slipknot S 41 +31 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 59-233 175 234-494 1-36 37-58 36 260 slipknot
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41 29-274 246 1-28 329-494 275-328 28 166 slipknot
Chain Sequence
DLSLSDINSTVEVPEGHSFWKTLLAYSGPGALVAVGYMDPGNWSTSITGGQNFQYLLLSIIVISSLLAMLLQNMAAKLGIVCQLDLAQAIRARTSRRLGFIFWILTELAIMATDIAEVIGAAIALYLLFKIPIFLAVVITVLDVFLLLLLNRIGFRKIEALVVCLIFVILFVFLYQIILSQPAWHQVAKGLIPSWASVQTSPKIGGQTPLSASLGIIGATIMPHNLFLHSAISQSRKIDRTDSSKVAEAVRFSNWDSNIQLSLAMVVNALLLIMGVAVFKSGAVQDPSFFGLYQALSNPDMVSNPVLAEAARSGVLSTLFAVALLASGQNSTITGTITGQVIMEGFIHLRLPLWLRRLVTRLIAIIPVVVCVAITSHQGSLDEHQALNNLMNNSQVFLALALPFSIVPLLMLTDSAAQMGNQFKNTRWVKVMGWLTVIILTLLNLISISSQIAGFFGDNPSSQDLLLSQVISIGIILAMIGLLIWTIIDIRRFT
publication title Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds.
pubmed doi rcsb
structure length 494
molecule tags Transport protein
source organism Eremococcus coleocola acs-139-v-col8
sequence length 494
total genus Genus: 184
molecule keywords Divalent metal cation transporter MntH
ec nomenclature
pdb deposition date 2019-11-29
KnotProt deposition date 2019-12-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01566 Nramp Natural resistance-associated macrophage protein
Image from the rcsb pdb (www.rcsb.org)
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