6WKR | KnotProt

Cysteine knot

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Help Cysteine knot data interpretation Full screen

				Loop	Piercing
view details				530-c-549-b-553-c-553	530-b-549

Chain Sequence

KRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYS--------------------------------------DKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCR--------------------------------------------------------------------------------------QVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP

sequence length	730
structure length	606
publication title	JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. pubmed doi rcsb
molecule tags	Gene regulation/dna
molecule keywords	Ubiquitin
source organism	Homo sapiens
missing residues	166-203, 324-409
ec nomenclature	ec 2.1.1.356: [Histone H3]-lysine(27) N-trimethyltransferase.
pdb deposition date	2020-04-16

Image from the rcsb pdb (www.rcsb.org)

6WKRC 6C23C 6C24C
similar chains in the KnotProt database (40% sequence similarity)

8EQVD 8FYHA 8VMIC 8VMLC 8VNVC 8VNZC
similar chains in the pdb database (40% sequence similarity)

#similar chains in the KnotProt database (40% sequence similarity)
6WKR C; 
#similar chains, but unknotted
6C24 C; 
#similar chains in the pdb database (40% sequence similarity)
8EQV D; 8FYH A; 8VMI C; 8VML C; 8VNV C; 8VNZ C;