6WKRC

Prc2-aebp2-jarid2 bound to h2ak119ub1 nucleosome
Cysteine knot
Loop Piercing
view details
530-c-549-b-553-c-553 530-b-549
Chain Sequence
KRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYS--------------------------------------DKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCR--------------------------------------------------------------------------------------QVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
sequence length 730
structure length 606
publication title JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.
pubmed doi rcsb
molecule tags Gene regulation/dna
molecule keywords Ubiquitin
source organism Homo sapiens
missing residues 166-203, 324-409
ec nomenclature ec 2.1.1.356: [Histone H3]-lysine(27) N-trimethyltransferase.
pdb deposition date 2020-04-16
Image from the rcsb pdb (www.rcsb.org)
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