6Y6NA

Structure of mature activin a with small molecule 2
Cysteine knot
Loop Piercing
view details
350-c-354-b-425-c-423 321-b-391
Chain Sequence
GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
sequence length 116
structure length 116
publication title Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
doi rcsb
molecule tags Signaling protein
molecule keywords Inhibin beta A chain
source organism Homo sapiens
ec nomenclature
pdb deposition date 2020-02-26
Image from the rcsb pdb (www.rcsb.org)
1NYUB 1S4YB 2ARPA 2ARVA 2B0UA 2P6AA 3B4VA 5HLYA 5HLZB
similar chains in the KnotProt database (40% sequence similarity)
None
similar chains in the pdb database (40% sequence similarity)

 
#similar chains in the KnotProt database (40% sequence similarity)
1NYU B; 1S4Y B; 2ARP A; 2ARV A; 2B0U A; 2P6A A; 3B4V A; 5HLY A; 5HLZ B; 
#similar chains, but unknotted

#similar chains in the pdb database (40% sequence similarity)


KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling
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