7LOKA

Structure of cd4 mimetic m48u1 in complex with bg505 sosip.664 hiv-1 env trimer and 17b fab
Cysteine knot
Loop Piercing
view details
331-c-378-b-445-c-418 331-b-385
Chain Sequence
NLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLCVN-------------------------------------------------------------------CNTSAITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQCTHGIKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPNIRQAHCNVSKATWNETLGKVVKQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFYCNTSGLFNS------------------------TWISDSITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLILTRDGGSTTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRR
sequence length 470
structure length 363
publication title Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
pubmed doi rcsb
molecule tags Viral protein/immune system
molecule keywords Envelope glycoprotein BG505 SOSIP.664 gp120
source organism Human immunodeficiency virus 1
missing residues 96-162, 269-292, 365-377, 427-429
ec nomenclature
pdb deposition date 2021-02-10
Image from the rcsb pdb (www.rcsb.org)
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