7LOOA

S-adenosyl methionine transferase cocrystallized with atp
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 15-262 248 1-14, 263-379 14 117 knot
Chain Sequence
HLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAG
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 17-273 257 1-16 349-379 274-348 16 31 slipknot
view details
2.1 17-357 341 358-379 1-2 3-16 2 21 slipknot
view details
2.1 16-348 333 1-3, 358-379 4-15, 349-357 3 22 slipknot
sequence length 379
structure length 379
publication title Protein and substrate flexibility contribute to enzymatic specificity in human and bacterial methionine adenosyltransferase
rcsb
molecule tags Transferase
molecule keywords S-adenosylmethionine synthase
source organism Escherichia coli 908573
total genus Genus: 140
ec nomenclature ec 2.5.1.6: Methionine adenosyltransferase.
pdb deposition date 2021-02-10
KnotProt deposition date 2021-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00438 S-AdoMet_synt_N S-adenosylmethionine synthetase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
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