S +31
|
S 3x +31
|
|
4qsiA
|
Crystal structure of human carbonic anhydrase isozyme ii with 5-{[(4-tert-buthyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}-2-chlorobenzenesulfonamide
|
S +31
|
S 3x +31
|
|
3sapA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-{[(5-butyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
S +31
|
S 6x +31
|
|
1cctA
|
Structure-assisted redesign of a protein-zinc binding site with femtomolar affinity
|
S +31
|
S 3x +31
|
|
4qtlA
|
Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
|
S +31
|
S 3x +31
|
|
3m2zA
|
Fragment tethered to carbonic anhydrase ii h64c mutant
|
S +31
|
S 3x +31
|
|
3p5lA
|
Human carbonic anhydrase complexed with sodium 4-cyano-4-phenylpiperidine-1-carbodithioate
|
S +31
|
S 3x +31
|
|
4kniA
|
Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide
|
S +31
|
S 7x +31
|
|
1bnuA
|
Carbonic anhydrase ii inhibitor
|
S +31
|
S 15x +31
|
|
4mlxA
|
Structure of a bidentate 3-hydroxy-4h-pyran-4-thione ligand bound to hcaii
|
S +31
|
S 3x +31
|
|
5jg5B
|
Human carbonic anhydrase ii (v121t/f131y) complexed with benzo[d]thiazole-2-sulfonamide
|
S +31
|
S 3x +31
|
|
3sbhA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
S +31
|
S 3x +31
|
|
1calA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
5jn1A
|
Carbonic anhydrase ix-mimic in complex with u-ch3
|
S +31
|
S 3x +31
|
|
3ks3A
|
High resolution structure of human carbonic anhydrase ii at 0.9 a
|
S +31
|
S 3x +31
|
|
4cnrA
|
Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion co2 capture
|
S +31
|
S 3x +31
|
|
3mmfA
|
Crystal structure of human carbonic anhydrase ii in complex with a 1,3,5-triazine-substituted benzenesulfonamide inhibitor
|
S +31
|
S 11x +31
|
|
2q1bA
|
Carbonic anhydrase ii in complex with saccharin
|
S +31
|
S 11x +31
|
|
1okmA
|
Carbonic anhydrase ii complex with the 1okm inhibitor 4-sulfonamide-[1-(4-aminobutane)]benzamide
|
S +31
|
S 3x +31
|
|
3s71B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
S +31
|
S 3x +31
|
|
3dcwA
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
S +31
|
S 3x +31
|
|
4idrX
|
Human carbonic anhydrase ii proton transfer double mutant
|
S +31
|
S 7x +31
|
|
3m1jA
|
The crystal structure of a nami a-carbonic anhydrase ii adduct discloses the mode of action of this novel anticancer metallodrug
|
S +31
|
S 3x +31
|
|
3hs4A
|
Human carbonic anhydrase ii complexed with acetazolamide
|
S +31
|
S 3x +31
|
|
6cjvA
|
Carbonic anhydrase ix-mimic in complex with sucralose
|
S +31
|
S 3x +31
|
|
4ruxA
|
Crystal structure of human carbonic anhydrase ii in complex with 4-(allyloxy)benzenesulfonamide
|
S +31
|
S 3x +31
|
|
5jgtB
|
Human carbonic anhydrase ii (f131y/l198a) complexed with 1,3-thiazole-2-sulfonamide
|
S +31
|
S 3x +31
|
|
5dsiA
|
Structure of co2 bound holo-form of human carbonic anhydrase ii with 0 sec (no) warming
|
S +31
|
S 3x +31
|
|
1rj6A
|
Crystal structure of the extracellular domain of murine carbonic anhydrase xiv in complex with acetazolamide
|
S +31
|
S 3x +31
|
|
5llcA
|
Crystal structure of human carbonic anhydrase isozyme ii with 3-(methylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide
|
S +31
|
S 3x +31
|
|
3dd0A
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
S +31
|
S 3x +31
|
|
4mo8A
|
The crystal structure of the human carbonic anhydrase ii in complex with n-[2-(2-methyl-5-nitro-1h-imidazol-1-yl)ethyl]sulfamide
|
S +31
|
S 3x +31
|
|
3s78B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
S +31
|
S 3x +31
|
|
3v3jA
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
S +31
|
S 3x +31
|
|
1g6vA
|
Complex of the camelid heavy-chain antibody fragment cab-ca05 with bovine carbonic anhydrase
|
S +31
|
S 3x +31
|
|
2it4A
|
X ray structure of the complex between carbonic anhydrase i and the phosphonate antiviral drug foscarnet
|
S +31
|
S 3x +31
|
|
5a6hA
|
Synthesis, carbonic anhydrase inhibition and protein x-ray structure of the unusual natural product primary sulfonamide psammaplin c
|
S +31
|
S 1x +31 +31
|
|
1koqA
|
Neisseria gonorrhoeae carbonic anhydrase
|
S +31
|
S 1x +31
|
|
1cvhA
|
Structural consequences of redesigning a protein-zinc binding site
|
S +31
|
S 11x +31
|
|
4qy3A
|
The crystal structure of the complex of hcaii with an ortho-substituted benzoic acid
|
S +31
|
S 4x +31
|
|
5ulnA
|
Synthesis of novel seleno ureido containing compounds as slc-0111 analogs. investigations on carbonic anhydrases activity, glutathione peroxidase and x-ray crystallography
|
S +31
|
S 3x +31
|
|
4g0cA
|
Neutron structure of acetazolamide-bound human carbonic anhydrase ii reveal molecular details of drug binding.
|
S +31
|
S 3x +31
|
|
5u0dA
|
Identification of a new zinc binding chemotype by fragment screening
|
S +31
|
S 3x +31
|
|
1v9iC
|
Crystal structure analysis of the site specific mutant (q253c) of bovine carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
1h9nA
|
H119n carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
3dvdA
|
X-ray crystal structure of mutant n62d of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
4zx1A
|
Engineered carbonic anhydrase ix mimic in complex with a glucosyl sulfamate inhibitor
|
S +31
|
S 3x +31
|
|
3hkuA
|
Human carbonic anhydrase ii in complex with topiramate
|
S +31
|
S 3x +31
|
|
4itoA
|
Human ca ii inhibition by novel sulfonamide
|
S +31
|
S 3x +31
|
|
3v3hB
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
S +31
|
S 3x +31
|
|
5bnlA
|
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins
|
S +31
|
S 4x -31
|
|
3e2dA
|
The 1.4 a crystal structure of the large and cold-active vibrio sp. alkaline phosphatase
|
S +31
|
S 3x +31
|
|
4ilxA
|
Structure of human carbonic anhydrase ii in complex with an adamantyl sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
2povA
|
The crystal structure of the human carbonic anhydrase ii in complex with 4-amino-6-chloro-benzene-1,3-disulfonamide
|
S +31
|
S 3x +31
|
|
5n1rA
|
Crystal structure of human carbonic anhydrase ii in complex with the inhibitor 4'-pyrazol-1-ylmethyl-biphenyl-4-sulfonamide
|
S +31
|
S 3x +31
|
|
5jq0A
|
Crystal structure of human carbonic anhydrase ii in complex with benzoxaborole at ph=8.7
|
S +31
|
S 11x +31
|
|
2hncA
|
Crystal structure of the human carbonic anhydrase ii in complex with the 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.
|
S +31
|
S 3x +31
|
|
2fmzA
|
Carbonic anhydrase activators. activation of isoforms i, ii, iv, va, vii and xiv with l- and d- phenylalanine, structure with d-phenylalanine.
|
S +31
|
S 3x +31
|
|
5cacA
|
Refined structure of human carbonic anhydrase ii at 2.0 angstroms resolution
|
S +31
|
S 3x +31
|
|
5flqA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
S +31
|
S 22x +31
|
|
5ca2A
|
Conformational mobility of his-64 in the thr-200 (right arrow) ser mutant of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
1t9nA
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
S +31
|
S 15x +31
|
|
4q8yA
|
Crystal structure of 2-hydroxyisoquinoline-1(2h)-thione bound to human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
5o07A
|
The crystal structure of the human carbonic anhydrase ii in complex with a nitroimidazole sulfamate inhibitor
|
S +31
|
S 3x +31
|
|
3qykA
|
Human carbonic anhydrase ii complexed with triple ring benzene sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
5n1sA
|
Crystal structure of human carbonic anhydrase ii in complex with the inhibitor 4-(1h-indol-2-yl)-benzenesulfonamide
|
S +31
|
S 3x +31
|
|
5e2rA
|
The crystal structure of the human carbonic anhydrase ii in complex with a 1,1'-biphenyl-4-sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
1cazA
|
Wild-type and e106q mutant carbonic anhydrase complexed with acetate
|
S +31
|
S 11x +31
|
|
4yxuA
|
Human carbonic anhydrase ii complexed with an inhibitor with a benzenesulfonamide group (4).
|
S +31
|
S 7x +31
|
|
4q78A
|
Structure-assisted design of carborane-based inhibitors of carbonic anhydrase
|
S +31
|
S 3x +31
|
|
4rh2A
|
Crystal structure of human carbonic anhydrase ii in complex with 2-(6-hydroxy-3-oxo-3h-xanthen-9-yl)-5-{3-1-(4-sulfamoyl-phenyl)-1h-[1,2,3]triazol-4-ylmethyl-thioureido}-benzoic acid
|
S +31
|
S 11x +31
|
|
1bnwA
|
Carbonic anhydrase ii inhibitor
|
S +31
|
S 23x +31
|
|
4jsaA
|
Benzenesulfonamide complexed with hcaii h94d
|
S +31
|
S 3x +31
|
|
1xq0A
|
Structure of human carbonic anhydrase ii with 4-[(3-bromo-4-o-sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
|
S +31
|
S 3x +31
|
|
1fqrA
|
X-ray crystal structure of cobalt-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
|
S +31
|
S 3x +31
|
|
5a25A
|
Rational engineering of a mesophilic carbonic anhydrase to an extreme halotolerant biocatalyst
|
S +31
|
S 3x +31
|
|
3ni5A
|
Carbonic anhydrase inhibitor: c1 family
|
S +31
|
S 3x +31
|
|
3k7kA
|
Crystal structure of the complex between carbonic anhydrase ii and anions
|
S +31
|
S 4x +31
|
|
6g4tA
|
The crystal structure of uninhibited c183s/c217s mutant of human ca vii
|
S +31
|
S 11x +31
|
|
4fvnA
|
Carbonic anhydrase ii in complex with n-(tetrahydropyrimidin-2(1h)-ylidene)sulfuric diamide
|
S +31
|
S 3x +31
|
|
1fr4A
|
X-ray crystal structure of copper-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
|
S +31
|
S 3x +31
|
|
1cahA
|
Structure of cobalt carbonic anhydrase complexed with bicarbonate
|
S +31
|
S 3x +31
|
|
5jmzA
|
Carbonic anhydrase ix-mimic in complex with u-no2
|
S +31
|
S 3x +31
|
|
3v3iB
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
S +31
|
S 11x +31
|
|
1oknA
|
Carbonic anhydrase ii complex with the 1okn inhibitor 4-sulfonamide-[1-(4-n-(5-fluorescein thiourea)butane)]
|
S +31
|
S 15x +31
|
|
4q7wA
|
Crystal structure of 1-hydroxy-6-methylpyridine-2(1h)-thione bound to human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
5amgA
|
Three dimensional structure of human carbonic anhydrase ii in complex with 2-(pentylsulfamoyl)-4-sulfamoylbenzoic acid
|
S +31
|
S 3x +31
|
|
1ugaA
|
Human carbonic anhydrase ii[hcaii] (e.c.4.2.1.1) mutant with ala 65 replaced by phe (a65f)
|
S +31
|
S 3x +31
|
|
4hu1A
|
Crystal structure of human carbonic anhydrase isozyme xiii with the inhibitor.
|
S +31
|
S 3x +31
|
|
5e2kA
|
Crystal structure of human carbonic anhydrase ii in complex with the 4-(3-aminophenyl)benzenesulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
1zsbA
|
Carbonic anhydrase ii mutant e117q, transition state analogue acetazolamide
|
S +31
|
S 3x +31
|
|
4n16A
|
Structure of cholate bound to human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
3t82A
|
Human carbonic anhydrase ii in complex with acetylated carbohydrate sulfamates
|
S +31
|
S 3x +31
|
|
4jszA
|
Benzenesulfonamide bound to hcaii h94c
|
S +31
|
S 64x -31
|
|
3q3qA
|
Crystal structure of spap: an novel alkaline phosphatase from bacterium sphingomonas sp. strain bsar-1
|
S +31
|
S 7x +31
|
|
3m2yA
|
Carbonic anhydrase ii in complex with novel sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
3k2fA
|
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma
|
S +31
|
S 3x +31
|
|
3kigA
|
Mutant carbonic anhydrase ii in complex with an azide and an alkyne
|
S +31
|
S 3x +31
|
|
3d9zA
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
S +31
|
S 3x +31
|
|
2q38A
|
Carbonic anhydrase ii in complex with saccharin at 1.95 angstrom
|
S +31
|
S 3x +31
|
|
2osmA
|
Inhibition of carbonic anhydrase ii by thioxolone: a mechanistic and structural study
|
S +31
|
S 3x +31
|
|
2nmxA
|
Structure of inhibitor binding to carbonic anhydrase i
|
S +31
|
S 7x +31
|
|
1ca3A
|
Unexpected ph-dependent conformation of his-64, the proton shuttle of carbonic anhydrase ii.
|
S +31
|
S 23x +31
|
|
3rj7A
|
Human carbonic anhydrase ii complexed with its inhibitor rhenium(i)triscarbonyl-cyclopentadienyl-carboxy-4-aminomethylbenzene-sulfonamide
|
S +31
|
S 3x +31
|
|
3rldA
|
Crystal structure of the y7i mutant of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
6g9uA
|
Three dimensional structure of human carbonic anhydrase ix in complex with sulfonamide
|
S +31
|
S 3x +31
|
|
5wgpA
|
Human carbonic anhydrase ix-mimic complexed with acek
|
S +31
|
S 3x +31
|
|
5fl4A
|
Three dimensional structure of human carbonic anhydrase ix in complex with 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide
|
S +31
|
S 7x +31
|
|
5eoiA
|
Crystal structure of copper bound human carbonic anhydrase ii
|
S +31
|
S 7x +31
|
|
4q7sA
|
Crystal structure of 1-hydroxy-4-methylpyridine-2(1h)-thione bound to human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
5ekjA
|
Human carbonic anhydrase ii complexed with a two-faced guest
|
S +31
|
S 3x +31
|
4
|
4zwiA
|
Surface lysine acetylated human carbonic anhydrase ii in complex with a sulfamate-based inhibitor
|
S +31
|
S 3x +31
|
|
4zwyA
|
Human carbonic anhydrase ii in complex with a glucosyl sulfamate inhibitor
|
S +31
|
S 3x +31
|
|
3tvoX
|
Human carbonic anhydrase ii proton transfer double mutant
|
S +31
|
S 3x +31
|
|
4jswA
|
Human carbonic anhydrase ii h94c
|
S +31
|
S 3x +31
|
|
3t83A
|
Human carbonic anhydrase ii in complex with acetylated carbohydrate sulfamates
|
S +31
|
S 3x +31
|
|
4hf3A
|
Activity enhancers of h64a variant of human carbonic anhydrase ii possess multiple binding sites within and around the enzyme structure
|
S +31
|
S 3x +31
|
|
3lxeA
|
Human carbonic anhydrase i in complex with topiramate
|
S +31
|
S 3x +31
|
|
3u7cA
|
Crystal structure of the v143i mutant of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
3u45X
|
Human carbonic anhydrase ii v143a
|
S +31
|
S 3x +31
|
|
1xpzA
|
Structure of human carbonic anhydrase ii with 4-[4-o-sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
|
S +31
|
S 3x +31
|
|
3hktA
|
Human carbonic anhydrase ii in complex with alpha-d-glucopyranosyl-(1->4)-1-thio-beta-d-glucopyranosylsulfonamide
|
S +31
|
S 3x +31
|
|
3p4vA
|
Human carbonic anhydrase ii in complex with (+)-xylariamide a
|
S +31
|
S 3x +31
|
|
3l14A
|
Human carbonic anhydrase ii complexed with althiazide
|
S +31
|
S 3x +31
|
|
1ugbA
|
Human carbonic anhydrase ii[hcaii] (e.c.4.2.1.1) mutant with ala 65 replaced by gly (a65g)
|
S +31
|
S 3x +31
|
|
3oilA
|
Human carbonic anhydrase ii mutant a65s, n67q (ca ix mimic) bound by 2-ethylestradiol 3-o-sulfamate
|
S +31
|
S 4x -31
|
|
5vpuA
|
Crystal structure of 2,3-bisphosphoglycerate-independent phosphoglycerate mutase bound to 3-phosphoglycerate, from acinetobacter baumannii
|
S +31
|
S 3x +31
|
|
3dvcA
|
X-ray crystal structure of mutant n62t of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
1cncA
|
Compensatory plastic effects in the redesign of protein-zinc binding sites
|
S +31
|
S 3x +31
|
|
1lg6A
|
Crystal structure analysis of hca ii mutant t199p in complex with thiocyanate
|
S +31
|
S 3x +31
|
|
3v3gB
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
S +31
|
S 3x +31
|
|
3hfpA
|
Crystal structure of teh complex between ca ii and the activator mai
|
S +31
|
S 15x +31
|
|
4q8xA
|
Crystal structure of 1-hydroxy-5-(trifluoromethyl)pyridine-2(1h)-thione bound to human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
2nn1A
|
Structure of inhibitor binding to carbonic anhydrase i
|
S +31
|
S 11x +31
|
|
1a42A
|
Human carbonic anhydrase ii complexed with brinzolamide
|
S +31
|
S 11x +31
|
|
1cnyA
|
Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase ii influence binding constants
|
S +31
|
S 3x +31
|
|
5dsmA
|
Structure of co2 released holo-form of human carbonic anhydrase ii with 25 min warming
|
S +31
|
S 3x +31
|
|
5dslA
|
Structure of co2 released holo-form of human carbonic anhydrase ii with 10 min warming
|
S +31
|
S 3x +31
|
|
4m2vA
|
Genetically engineered carbonic anhydrase ix in complex with brinzolamide
|
S +31
|
S 3x +31
|
|
3s77B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
S +31
|
S 3x +31
|
|
5yuiA
|
Co2 release in human carbonic anhydrase ii crystals: reveal histidine 64 and solvent dynamics
|
S +31
|
S 3x +31
|
|
5n0eA
|
Crystal structure of human carbonic anhydrase ii in complex with (s)-4-(6,7-dihydroxy-1-phenyl-3,4-tetrahydroisoquinoline-1h-2-carbonyl)benzenesulfonamide.
|
S +31
|
S 3x +31
|
|
5llhA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-(1,3-benzothiazol-2-ylthio)-2,3,5,6-tetrafluorobenzenesulfonamide
|
S +31
|
S 7x +31
|
|
5fnkA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
S +31
|
S 3x +31
|
|
6d1mA
|
Design, synthesis, and x-ray of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects
|
S +31
|
S 3x +31
|
|
1cvdA
|
Structural consequences of redesigning a protein-zinc binding site
|
S +31
|
S 3x +31
|
|
3m1wA
|
Carbonic anhyrdase ii mutant w5ch64c with closed disulfide bond in complex with sulfate
|
S +31
|
S 3x +31
|
|
5fngA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
S +31
|
S 3x +31
|
|
3uyqA
|
Hca 3
|
S +31
|
S 23x +31
|
|
1bnvA
|
Carbonic anhydrase ii inhibitor
|
S +31
|
S 3x +31
|
|
3m5sA
|
Carbonic anhydrase ii mutant h64c in complex with carbonate
|