4UF6A

Uch-l5 in complex with ubiquitin-propargyl bound to an activating fragment of ino80g
Warning
  • Chain breaks within knot 52 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Knot K -52 -31 -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
-52 6-219 214 1-5, 220-314 5 95 knot
view details
-31 5-162 158 1-4 216-314 163-215 4 99 slipknot
Chain Sequence
GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMF-----------DAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEESAIQSEVAKNQ-----------MLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQ
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
4.4m 9-208 200 1-8, 209-292 8 84 knot
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2.1m 5-160 156 1-4 167-292 161-166 4 126 slipknot
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2.1m 7-172 166 1-6 191-292 173-190 6 102 slipknot
view details
3.1m 8-192 185 1-7 203-292 193-202 7 90 slipknot
view details
2.1m 6-151 146 1-2, 160-292 3-5, 152-159 2 133 slipknot
sequence length 314
structure length 292
publication title Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G
rcsb
molecule tags Hydrolase
molecule keywords POLYUBIQUITIN-B
source organism Homo sapiens
missing residues 145-155, 241-251
total genus Genus: 97
ec nomenclature
pdb deposition date 2014-12-23
KnotProt deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
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