5DLVA

Crystal structure of autotaxin (enpp2) with tauroursodeoxycholic acid (tudca)
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 116-301 186 1-115 432-804 302-431 115 373 slipknot
Chain Sequence
GSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPLDV-------CFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPDEVSRPNYPGIMYLQSEFDLGCTCDHTKGSTK----------------ERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWAYFQRVLVKKYASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCASSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 46-300 255 1-45 306-781 301-305 45 476 slipknot
view details
3.1 114-303 190 1-113 423-781 304-422 113 359 slipknot
view details
3.1 114-422 309 1-113 424-781 423-423 113 358 slipknot
view details
2.1 32-423 392 1-31 426-781 424-425 31 356 slipknot
view details
2.1 42-423 382 1-31, 426-781 32-41, 424-425 31 356 slipknot
view details
2.1 56-423 368 1-41, 426-781 42-55, 424-425 41 356 slipknot
view details
2.1 74-301 228 1-57, 304-781 58-73, 302-303 57 478 slipknot
view details
2.1 87-300 214 1-72, 304-781 73-86, 301-303 72 478 slipknot
view details
2.1 88-301 214 1-86, 304-781 87-87, 302-303 86 478 slipknot
missing residues 406-412, 515-530
publication title Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling
doi rcsb
structure length 781
molecule tags Hydrolase
source organism Rattus norvegicus
sequence length 804
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
ec nomenclature
pdb deposition date 2015-09-07
KnotProt deposition date 2016-04-15
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling