5TCDA

Human alkaline sphingomyelinase (enpp7) in complex with phosphocholine
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 9-217 209 1-8 336-388 218-335 8 53 slipknot
Chain Sequence
QNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTES
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5



Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 6-217 212 1-5 224-388 218-223 5 165 slipknot
view details
2.1 8-219 212 1-7 328-388 220-327 7 61 slipknot
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3.1 6-328 323 1-5 334-388 329-333 5 55 slipknot
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2.1 9-283 275 1-7, 293-388 8-8, 284-292 7 96 slipknot
view details
2.1 10-263 254 1-7, 272-388 8-9, 264-271 7 117 slipknot
sequence length 388
structure length 388
publication title Crystal Structure of the Human Alkaline Sphingomyelinase Provides Insights into Substrate Recognition.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
source organism Homo sapiens
ec nomenclature
pdb deposition date 2016-09-14
KnotProt deposition date 2017-03-26
Image from the rcsb pdb (www.rcsb.org)
5TCDA 5UDYA
similar chains in the KnotProt database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 5TCD A;  5UDY A; 
               
               
           

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