5TPQA

E. coli alkaline phosphatase d101a, d153a, r166s, e322a, k328a mutant
Slipknot S +31
Knot core rangeKnot core lengthKnot tails rangeSlipknot tails rangeSlipknot loops rangeN-end lengthC-end lengthType
view details
+31 41-361 321 1-40 412-446 362-411 40 35 slipknot
Chain Sequence
ENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTASAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQAATPAALVAHVTSSKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVAGASIDAQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKWSHP
sequence length 446
structure length 446
publication title Differential Catalytic Promiscuity of the Alkaline Phosphatase Superfamily Bimetallo Core Reveals Mechanistic Features Underlying Enzyme Evolution
doi rcsb
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
source organism Escherichia coli (strain k12)
ec nomenclature
pdb deposition date2016-10-20
KnotProt deposition date2017-11-01
Image from the rcsb pdb (www.rcsb.org)
3TG0A 3BDGA 3BDGB 3BDFA 1Y6VA 3BDHA 1ED9A 1ED8A 1Y7AA 1B8JA 1ALKA 1EW9A 1KH5A 3CMRA 5C66A 2G9YA 1URAA 1HQAA 1ALIA 1URBA 2GA3A 1EW8A 1HJKA 1KHJA 3DYCA 5TPQA 1ANJA 1KH7A 1AJAA 1AJBA 1AJDA 1AJCA 2ANHA 1KH4A 1KHKA 4YR1A 1ELXA 1ANIA 1ELZA 1ALJA 1KHLA 1ELYA 1ALHA 1KH9A 3DPCA 1KHNA 4KM4A
similar chains in the KnotProt database (40% sequence similarity)
3TG0B 3TG0C 3TG0D 3BDFB 1Y6VB 3BDHB 1ED9B 1ED8B 1Y7AB 1B8JB 1ALKB 1EW9B 1KH5B 3CMRB 5C66B 2G9YB 1URAB 1HQAB 1ALIB 1URBB 2GA3B 1EW8B 1HJKB 1KHJB 3DYCB 5TPQB 1ANJB 1KH7B 1AJAB 1AJBB 1AJDB 1AJCB 2ANHB 1KH4B 1KHKB 4YR1B 1ELXB 1ANIB 1ELZB 1ALJB 1KHLB 1ELYB 1ALHB 1KH9B 3DPCB 1KHNB 4KM4B 5JTLE
similar chains in the pdb database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 3TG0 A;  3BDG A;  3BDG B;  3BDF A;  1Y6V A;  3BDH A;  1ED9 A;  1ED8 A;  1Y7A A;  1B8J A;  1ALK A;  1EW9 A;  1KH5 A;  3CMR A;  5C66 A;  2G9Y A;  1URA A;  1HQA A;  1ALI A;  1URB A;  2GA3 A;  1EW8 A;  1HJK A;  1KHJ A;  3DYC A;  5TPQ A;  1ANJ A;  1KH7 A;  1AJA A;  1AJB A;  1AJD A;  1AJC A;  2ANH A;  1KH4 A;  1KHK A;  4YR1 A;  1ELX A;  1ANI A;  1ELZ A;  1ALJ A;  1KHL A;  1ELY A;  1ALH A;  1KH9 A;  3DPC A;  1KHN A;  4KM4 A; 
               
               
           
#similar chains in the pdb database (40% sequence similarity)
 3TG0 B;  3TG0 C;  3TG0 D;  3BDF B;  1Y6V B;  3BDH B;  1ED9 B;  1ED8 B;  1Y7A B;  1B8J B;  1ALK B;  1EW9 B;  1KH5 B;  3CMR B;  5C66 B;  2G9Y B;  1URA B;  1HQA B;  1ALI B;  1URB B;  2GA3 B;  1EW8 B;  1HJK B;  1KHJ B;  3DYC B;  5TPQ B;  1ANJ B;  1KH7 B;  1AJA B;  1AJB B;  1AJD B;  1AJC B;  2ANH B;  1KH4 B;  1KHK B;  4YR1 B;  1ELX B;  1ANI B;  1ELZ B;  1ALJ B;  1KHL B;  1ELY B;  1ALH B;  1KH9 B;  3DPC B;  1KHN B;  4KM4 B;  5JTL E; 
           

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