6F6NA

Crystal structure of ebolavirus glycoprotein in complex with sertraline
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 77-140 64 1-76 145-326 141-144 76 182 slipknot
Chain Sequence
SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQA----------------------GYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTWAFWETSEELSFTVVXXXXXXX
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 57-138 82 1-56 147-253 139-146 56 107 slipknot
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2.1 78-138 61 1-57, 146-253 58-77, 139-145 57 108 slipknot
view details
1.1 82-139 58 1-77, 145-253 78-81, 140-144 77 109 slipknot
sequence length 326
structure length 253
publication title Target identification and mode of action of four chemically divergent drugs against Ebola virus infection.
pubmed doi rcsb
molecule tags Viral protein
molecule keywords Envelope glycoprotein,Envelope glycoprotein,GP1
source organism Zaire ebolavirus (strain mayinga-76)
missing residues 159-180, 254-256, 263-271, 281-319
total genus Genus: 64
ec nomenclature
pdb deposition date 2017-12-05
KnotProt deposition date 2018-01-03
Image from the rcsb pdb (www.rcsb.org)
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