4GTWA

Crystal structure of mouse enpp1 in complex with amp
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 30-236 207 1-29 360-733 237-359 29 374 slipknot
Chain Sequence
KSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDP----------------EDDDIYHMTVPYGRPRILLKQHRVCLLQQQQFLTGYSLDLLMPLWASYTFLSNDSNCLYQDLRIPLSPVH-------KCSYYKSNSKLSYGFLTPPRLNHIYSEALLTSNIVPMYQSFQVIW----HYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFS
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 16-234 219 1-15 240-706 235-239 15 467 slipknot
view details
3.1 30-236 207 1-29 348-706 237-347 29 359 slipknot
view details
3.1 30-347 318 1-29 358-706 348-357 29 349 slipknot
view details
2.1 31-305 275 1-29, 310-706 30-30, 306-309 29 397 slipknot
sequence length 733
structure length 706
publication title Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
source organism Mus musculus
missing residues 443-458, 513-519, 558-561
total genus Genus: 188
ec nomenclature ec 3.1.4.1: Phosphodiesterase I.
ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2012-08-29
KnotProt deposition date 2014-07-31
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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