6EKIA

Structure of a hyperthermostable carbonic anhydrase identified from an active hydrothermal vent chimney
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 26-219 194 1-25, 220-222 25 2 slipknot
Chain Sequence
HWSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDISRIVEAELEKIKINYSSGGSSITNNGHTIKVSYEPGSYIIVDGIRFELKQFHFHAPSEHTIKGKSYPFEAHFVHADKDGNLAVIGVIFKEGKKNPIIEKIWENLPEAGKTIKLAHKINAYDLLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMGGDTNRPVQPLNARMIMEMD
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 3x +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 27-201 175 1-26, 202-205 26 4 knot
Fingerprint Knot forming loop Loop type
K +31 His32 ... His117 <->
Bridging ionZn301
<-> His136 ...
Chain closureAsp253 <-> His32
probabilistic
K +31
Chain closureHis32 <-> Asp253
... His119 <->
Bridging ionZn301
<-> His117 ... His32
probabilistic
K +31 His32 ... His119 <->
Bridging ionZn301
<-> His136 ...
Chain closureAsp253 <-> His32
probabilistic
Chain Sequence
HWSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDISRIVEAELEKIKINYSSGGSSITNNGHTIKVSYEPGSYIIVDGIRFELKQFHFHAPSEHTIKGKSYPFEAHFVHADKDGNLAVIGVIFKEGKKNPIIEKIWENLPEAGKTIKLAHKINAYDLLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMGGDTNRPVQPLNARMIMEMD
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 28-221 194 1-27, 222-222 27 1 knot
view details
2.1 29-217 189 1-28 222-222 218-221 28 1 slipknot
sequence length 222
structure length 222
publication title Structure of a hyperthermostable carbonic anhydrase identified from an active hydrothermal vent chimney.
pubmed doi rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase
source organism Persephonella marina
total genus Genus: 60
ec nomenclature
pdb deposition date 2017-09-26
KnotProt deposition date 2018-10-20
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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