7CWWA

Crystal structure of tsrl
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 127
Knot K +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 140-339 200 1-139, 340-362 139 23 knot
Chain Sequence
TSEQKDLTVSVPWSVQEDLLLDVAAPLLDESVELGETDSWFYLRENHGGRPFLRLRFASRSPSVERRLKSRILAHVGPTIDAGDVFTYQPYNHEHDWLGGTAGLGLAENFWTETTPLALDTLRATRGNRALRLAVAFDFLVCTGVMLAPHLPPSIAKFGYKAGYLSYLATFEGYMLLIRDPEGTRAKHAQRYEKNRELLRPRLRTLVEQMSEPDGELTDVPELAREWLVRLRDYVPALQKGFDEGRFYLYATPRKAETA------------PDVEWLSDLPEPPVAGIHRAIADNTYYQGMIREDRRFLASRLAQAYTNWHLYRLGFLLADRYTLFYLIARAFEEEYDLDAAALIRSVRPEA
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 133-342 210 1-132, 343-362 132 20 knot
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2.1 136-334 199 1-98, 347-362 99-135, 335-346 98 16 slipknot
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2.1 136-346 211 1-132, 350-362 133-135, 347-349 132 13 slipknot
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2.1 137-340 204 1-135, 350-362 136-136, 341-349 135 13 slipknot
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2.1 143-336 194 1-136, 350-362 137-142, 337-349 136 13 slipknot
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3.1 143-349 207 350-362 1-132 133-142 132 12 slipknot
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2.1 144-346 203 1-142, 349-362 143-143, 347-348 142 14 slipknot
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2.1 144-349 206 350-362 1-142 143-143 142 12 slipknot
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2.1 145-343 199 1-143, 349-362 144-144, 344-348 143 14 slipknot
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2.1 145-351 207 352-362 1-143 144-144 143 10 slipknot
sequence length 362
structure length 350
publication title crystal structure of TsrL
rcsb
molecule tags Antibiotic
molecule keywords TsrE
source organism Streptomyces laurentii
missing residues 260-271
total genus Genus: 127
ec nomenclature
pdb deposition date 2020-08-31
KnotProt deposition date 2021-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14028 Lant_dehydr_C Lantibiotic biosynthesis dehydratase C-term
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling