1D4NA

Human serum transferrin
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 2x +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 20-161 142 1-19, 162-220 19 58 slipknot
Fingerprint Knot forming loop Loop type
K +31 Asp63 <->
Bridging ionFe339
<-> Tyr188 ... Cys331 <-> Cys137 ... Asp63
ion-based
K +31 Asp63 <->
Bridging ionFe339
<-> Tyr188 ... Cys227 <-> Cys241 ... Cys331 <-> Cys137 ... Asp63
ion-based
Chain Sequence
DKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKESTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTC
sequence length 329
structure length 329
publication title Crystal structures of two mutants (K206Q, H207E) of the N-lobe of human transferrin with increased affinity for iron.
pubmed rcsb
molecule tags Metal transport
molecule keywords TRANSFERRIN
source organism Homo sapiens
total genus Genus: 105
ec nomenclature
pdb deposition date 1999-10-04
KnotProt deposition date 2018-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00405 Transferrin Transferrin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.190.10 Alpha Beta 3-Layer(aba) Sandwich D-Maltodextrin-Binding Protein; domain 2 Periplasmic binding protein-like II 1d4nA01
3.40.190.10 Alpha Beta 3-Layer(aba) Sandwich D-Maltodextrin-Binding Protein; domain 2 Periplasmic binding protein-like II 1d4nA02
3.40.190.10 Alpha Beta 3-Layer(aba) Sandwich D-Maltodextrin-Binding Protein; domain 2 Periplasmic binding protein-like II 1d4nA01
3.40.190.10 Alpha Beta 3-Layer(aba) Sandwich D-Maltodextrin-Binding Protein; domain 2 Periplasmic binding protein-like II 1d4nA02
1N7XA 1B3EA 2O84X 1A8FA 1DTGA 1A8EA 3FGSA 1FQFA 3O97A 1FQEA 1OQHA 1OQGA 1JQFA 1D4NA 2O7UA 1N7WA 1D3KA 1N84A
chains in the KnotProt database with same CATH superfamily
1N7XA 1B3EA 2O84X 1A8FA 1DTGA 1A8EA 3FGSA 1FQFA 3O97A 1FQEA 1OQHA 1OQGA 1JQFA 1D4NA 2O7UA 1N7WA 1D3KA 1N84A
chains in the KnotProt database with same CATH topology
1N7XA 1B3EA 2O84X 1A8FA 1DTGA 1A8EA 3FGSA 1FQFA 3O97A 1FQEA 1OQHA 1OQGA 1JQFA 1D4NA 2O7UA 1N7WA 1D3KA 1N84A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1N7X A;  1B3E A;  2O84 X;  1A8F A;  1DTG A;  1A8E A;  3FGS A;  1FQF A;  3O97 A;  1FQE A;  1OQH A;  1OQG A;  1JQF A;  1D4N A;  2O7U A;  1N7W A;  1D3K A;  1N84 A; 
#chains in the KnotProt database with same CATH topology
 1N7X A;  1B3E A;  2O84 X;  1A8F A;  1DTG A;  1A8E A;  3FGS A;  1FQF A;  3O97 A;  1FQE A;  1OQH A;  1OQG A;  1JQF A;  1D4N A;  2O7U A;  1N7W A;  1D3K A;  1N84 A; 
#chains in the KnotProt database with same CATH homology
 1N7X A;  1B3E A;  2O84 X;  1A8F A;  1DTG A;  1A8E A;  3FGS A;  1FQF A;  3O97 A;  1FQE A;  1OQH A;  1OQG A;  1JQF A;  1D4N A;  2O7U A;  1N7W A;  1D3K A;  1N84 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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