2NWXA

Crystal structure of gltph in complex with l-aspartate and sodium ions
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 147
Slipknot S +31 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 50-310 261 1-49 371-405 311-370 49 35 slipknot
Chain Sequence
VLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQF-----PPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 39-288 250 1-38 310-400 289-309 38 91 slipknot
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3.1 36-324 289 1-35 337-400 325-336 35 64 slipknot
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3.1 16-352 337 1-5, 362-400 6-15, 353-361 5 39 slipknot
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3.1 36-312 277 1-6, 325-400 7-35, 313-324 6 76 slipknot
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3.1 43-350 308 1-10, 369-400 11-42, 351-368 10 32 slipknot
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2.1 42-368 327 1-10, 371-400 11-41, 369-370 10 30 slipknot
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3.1 38-312 275 1-35, 326-400 36-37, 313-325 35 75 slipknot
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3.1 38-325 288 1-35, 327-400 36-37, 326-326 35 74 slipknot
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3.1 38-326 289 1-35, 329-400 36-37, 327-328 35 72 slipknot
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2.1 54-308 255 1-41, 329-400 42-53, 309-328 41 72 slipknot
sequence length 405
structure length 400
publication title Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords 425aa long hypothetical proton glutamate symport protein
source organism Pyrococcus horikoshii
missing residues 112-116
total genus Genus: 147
ec nomenclature
pdb deposition date 2006-11-16
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3860.10 Mainly Alpha Orthogonal Bundle Proton glutamate symport protein Proton glutamate symport protein 2nwxA00
2NWWA 3V8FA 3KBCA 2NWXA 2NWLA 1XFHA
chains in the KnotProt database with same CATH superfamily
2NWWA 3V8FA 3KBCA 2NWXA 2NWLA 1XFHA
chains in the KnotProt database with same CATH topology
2NWWA 3V8FA 3KBCA 2NWXA 2NWLA 1XFHA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 2NWW A;  3V8F A;  3KBC A;  2NWX A;  2NWL A;  1XFH A; 
#chains in the KnotProt database with same CATH topology
 2NWW A;  3V8F A;  3KBC A;  2NWX A;  2NWL A;  1XFH A; 
#chains in the KnotProt database with same CATH homology
 2NWW A;  3V8F A;  3KBC A;  2NWX A;  2NWL A;  1XFH A;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling