2NWLA

Crystal structure of gltph in complex with l-asp
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 147
Slipknot S +31 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 56-312 257 1-55 371-407 313-370 55 37 slipknot
Chain Sequence
YPVLIKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQF-----PPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 38-291 254 1-37 315-402 292-314 37 88 slipknot
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2.1 42-326 285 1-41 339-402 327-338 41 64 slipknot
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3.1 14-352 339 1-13 365-402 353-364 13 38 slipknot
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3.1 41-356 316 1-40 371-402 357-370 40 32 slipknot
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2.1 41-370 330 1-40 373-402 371-372 40 30 slipknot
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3.1 36-314 279 1-2, 327-402 3-35, 315-326 2 76 slipknot
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2.1 22-352 331 1-13, 357-402 14-21, 353-356 13 46 slipknot
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3.1 41-314 274 1-35, 327-402 36-40, 315-326 35 76 slipknot
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2.1 60-310 251 1-39, 326-402 40-59, 311-325 39 77 slipknot
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2.1 59-350 292 1-46, 366-402 47-58, 351-365 46 37 slipknot
sequence length 407
structure length 402
publication title Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords glutamate symport protein
source organism Pyrococcus horikoshii
missing residues 114-118
total genus Genus: 147
ec nomenclature
pdb deposition date 2006-11-15
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3860.10 Mainly Alpha Orthogonal Bundle Proton glutamate symport protein Proton glutamate symport protein 2nwlA00
2NWWA 3V8FA 3KBCA 2NWXA 2NWLA 1XFHA
chains in the KnotProt database with same CATH superfamily
2NWWA 3V8FA 3KBCA 2NWXA 2NWLA 1XFHA
chains in the KnotProt database with same CATH topology
2NWWA 3V8FA 3KBCA 2NWXA 2NWLA 1XFHA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 2NWW A;  3V8F A;  3KBC A;  2NWX A;  2NWL A;  1XFH A; 
#chains in the KnotProt database with same CATH topology
 2NWW A;  3V8F A;  3KBC A;  2NWX A;  2NWL A;  1XFH A; 
#chains in the KnotProt database with same CATH homology
 2NWW A;  3V8F A;  3KBC A;  2NWX A;  2NWL A;  1XFH A;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling