1D4N | KnotProt

Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!

Knot K 2x +3₁

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The Resolver thinks Pdb

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reading 329 atoms

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reading 329 atoms

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Help Knotting data interpretation Full screen

				Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details			+ 3₁	20-161	142	1-19, 162-220			19	58	slipknot
view details			+ 3₁	20-161	142	1-19, 162-207			19	46	knot

			Fingerprint	Knot forming loop	Loop type
knots details			K +3₁	Asp63 <-> Bridging ionFe339 <-> Tyr188 ... Cys331 <-> Cys137 ... Asp63	ion-based	color sequence
knots details			K +3₁	Asp63 <-> Bridging ionFe339 <-> Tyr188 ... Cys227 <-> Cys241 ... Cys331 <-> Cys137 ... Asp63	ion-based	color sequence

Chain Sequence

DKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKESTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTC

sequence length	329
structure length	329
publication title	Crystal structures of two mutants (K206Q, H207E) of the N-lobe of human transferrin with increased affinity for iron. pubmed rcsb
molecule tags	Metal transport
molecule keywords	TRANSFERRIN
source organism	Homo sapiens
total genus	Genus: 105
ec nomenclature
pdb deposition date	1999-10-04
KnotProt deposition date	2018-10-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00405	Transferrin	Transferrin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein; domain 2	Periplasmic binding protein-like II	1d4nA01
3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein; domain 2	Periplasmic binding protein-like II	1d4nA02
3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein; domain 2	Periplasmic binding protein-like II	1d4nA01
3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein; domain 2	Periplasmic binding protein-like II	1d4nA02

1A8FA 2O7UA 1N84A 1N7XA 1A8EA 1FQFA 1OQHA 3FGSA 1FQEA 1D3KA 1N7WA 1DTGA 3O97A 1B3EA 1JQFA 1D4NA 2O84X 1OQGA
chains in the KnotProt database with same CATH superfamily

1A8FA 2O7UA 1N84A 1N7XA 1A8EA 1FQFA 1OQHA 3FGSA 1FQEA 1D3KA 1N7WA 1DTGA 3O97A 1B3EA 1JQFA 1D4NA 2O84X 1OQGA
chains in the KnotProt database with same CATH topology

1A8FA 2O7UA 1N84A 1N7XA 1A8EA 1FQFA 1OQHA 3FGSA 1FQEA 1D3KA 1N7WA 1DTGA 3O97A 1B3EA 1JQFA 1D4NA 2O84X 1OQGA
chains in the KnotProt database with same CATH homology

#chains in the KnotProt database with same CATH superfamily
 1A8F A;  2O7U A;  1N84 A;  1N7X A;  1A8E A;  1FQF A;  1OQH A;  3FGS A;  1FQE A;  1D3K A;  1N7W A;  1DTG A;  3O97 A;  1B3E A;  1JQF A;  1D4N A;  2O84 X;  1OQG A; 
#chains in the KnotProt database with same CATH topology
 1A8F A;  2O7U A;  1N84 A;  1N7X A;  1A8E A;  1FQF A;  1OQH A;  3FGS A;  1FQE A;  1D3K A;  1N7W A;  1DTG A;  3O97 A;  1B3E A;  1JQF A;  1D4N A;  2O84 X;  1OQG A; 
#chains in the KnotProt database with same CATH homology
 1A8F A;  2O7U A;  1N84 A;  1N7X A;  1A8E A;  1FQF A;  1OQH A;  3FGS A;  1FQE A;  1D3K A;  1N7W A;  1DTG A;  3O97 A;  1B3E A;  1JQF A;  1D4N A;  2O84 X;  1OQG A;

1A8EA 1A8FA 1N84A 1SUVC 3S9LC 3S9MC 1BP5A 1BTJA
similar chains in the KnotProt database (40% sequence similarity)

3QYTA
similar chains in the pdb database (40% sequence similarity)

#similar chains in the KnotProt database (40% sequence similarity)
1A8E A; 1A8F A; 1N84 A; 1SUV C; 3S9L C; 3S9M C; 
#similar chains, but unknotted
1BTJ A; 
#similar chains in the pdb database (40% sequence similarity)
3QYT A;

1D4NA

Knot K 2x +31

Chain Sequence

pfam database annotations

Knot K 2x +3₁