K 3.1, 2.1
|
|
1h9nA
|
H119n carbonic anhydrase ii
|
K 3.1, 2.1
|
|
1g0fA
|
Site-specific mutant (his64 replaced with ala) of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3v2mA
|
Effect of sucrose and glycerol as cryoprotectans, on the inhibition of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3v3hB
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
K 3.1, 2.1
|
|
1v9iC
|
Crystal structure analysis of the site specific mutant (q253c) of bovine carbonic anhydrase ii
|
K 3.1, 2.1
|
|
5ulnA
|
Synthesis of novel seleno ureido containing compounds as slc-0111 analogs. investigations on carbonic anhydrases activity, glutathione peroxidase and x-ray crystallography
|
K 3.1, 2.1
|
|
4qy3A
|
The crystal structure of the complex of hcaii with an ortho-substituted benzoic acid
|
K 3.1, 2.1
|
|
5u0fA
|
Identification of a new zinc binding chemotype by fragment screening
|
K 3.1, 2.1
|
|
2wd3A
|
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template
|
K 3.1, 2.1
|
|
5vgyA
|
Identification of a new zinc binding chemotype by fragment screening
|
K 3.1, 2.1
|
|
5fdcA
|
Crystal structure of human carbonic anhydrase ii in complex with the anticonvulsant sulfamide jnj-26990990 and its s,s-dioxide analog.
|
K 3.1, 2.1
|
|
3s78B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
K 3.1, 2.1
|
|
4mo8A
|
The crystal structure of the human carbonic anhydrase ii in complex with n-[2-(2-methyl-5-nitro-1h-imidazol-1-yl)ethyl]sulfamide
|
K 3.1, 2.1
|
|
4e5qA
|
Human carbonic anhydrase ii in complex with cyanate
|
K 3.1, 2.1
|
|
4g0cA
|
Neutron structure of acetazolamide-bound human carbonic anhydrase ii reveal molecular details of drug binding.
|
K 3.1, 2.1
|
|
5u0dA
|
Identification of a new zinc binding chemotype by fragment screening
|
K 3.1, 2.1
|
|
3n0nA
|
Crystal structure of human carbonic anhydrase ii in complex with a benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
|
4mdmA
|
Nido-carborane carbonic anhydrase inhibitor
|
K 3.1, 2.1
|
|
5dsiA
|
Structure of co2 bound holo-form of human carbonic anhydrase ii with 0 sec (no) warming
|
K 3.1, 2.1
|
|
5jgtB
|
Human carbonic anhydrase ii (f131y/l198a) complexed with 1,3-thiazole-2-sulfonamide
|
K 3.1, 2.1
|
|
5a6hA
|
Synthesis, carbonic anhydrase inhibition and protein x-ray structure of the unusual natural product primary sulfonamide psammaplin c
|
K 3.1, 2.1
|
|
3m1jA
|
The crystal structure of a nami a-carbonic anhydrase ii adduct discloses the mode of action of this novel anticancer metallodrug
|
K 3.1, 2.1
|
|
4idrX
|
Human carbonic anhydrase ii proton transfer double mutant
|
K 3.1, 2.1
|
|
3dd0A
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
K 3.1, 2.1
|
|
1okmA
|
Carbonic anhydrase ii complex with the 1okm inhibitor 4-sulfonamide-[1-(4-aminobutane)]benzamide
|
K 3.1, 2.1
|
|
5llcA
|
Crystal structure of human carbonic anhydrase isozyme ii with 3-(methylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide
|
K 3.1, 2.1
|
|
4q8zA
|
Crystal structure of 1-hydroxy-4-methylpyridin-2(1h)-one bound to human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3mmfA
|
Crystal structure of human carbonic anhydrase ii in complex with a 1,3,5-triazine-substituted benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
|
5jn1A
|
Carbonic anhydrase ix-mimic in complex with u-ch3
|
K 3.1, 2.1
|
|
4qjmA
|
Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
|
K 3.1, 2.1
|
|
4ruxA
|
Crystal structure of human carbonic anhydrase ii in complex with 4-(allyloxy)benzenesulfonamide
|
K 3.1, 2.1
|
|
6cjvA
|
Carbonic anhydrase ix-mimic in complex with sucralose
|
K 3.1, 2.1
|
|
3hs4A
|
Human carbonic anhydrase ii complexed with acetazolamide
|
K 3.1, 2.1
|
|
3sbhA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
K 3.1, 2.1
|
|
5jg5B
|
Human carbonic anhydrase ii (v121t/f131y) complexed with benzo[d]thiazole-2-sulfonamide
|
K 3.1, 2.1
|
|
4mlxA
|
Structure of a bidentate 3-hydroxy-4h-pyran-4-thione ligand bound to hcaii
|
K 3.1, 2.1
|
|
3s71B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
K 3.1, 2.1
|
|
4kniA
|
Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide
|
K 3.1, 2.1
|
|
2q1bA
|
Carbonic anhydrase ii in complex with saccharin
|
K 3.1, 2.1
|
|
3dv7A
|
Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase ii (n62a)
|
K 3.1, 2.1
|
|
4cnrA
|
Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion co2 capture
|
K 3.1, 2.1
|
|
3ks3A
|
High resolution structure of human carbonic anhydrase ii at 0.9 a
|
K 3.1, 2.1
|
|
6bbsA
|
Joint x-ray/neutron structure of human carbonic anhydrase ii in complex with brinzolamide
|
K 3.1, 2.1
|
|
3v7xA
|
Complex of human carbonic anhydrase ii with n-[2-(3,4-dimethoxyphenyl)ethyl]-4-sulfamoylbenzamide
|
K 3.1, 2.1
|
|
4ht2A
|
Crystal structure of human carbonic anhydrase isozyme xii with the inhibitor.
|
K 3.1, 2.1
|
|
1calA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
4qtlA
|
Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
|
K 3.1, 2.1
|
|
4qsiA
|
Crystal structure of human carbonic anhydrase isozyme ii with 5-{[(4-tert-buthyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}-2-chlorobenzenesulfonamide
|
K 3.1, 2.1
|
|
3p5lA
|
Human carbonic anhydrase complexed with sodium 4-cyano-4-phenylpiperidine-1-carbodithioate
|
K 3.1, 2.1
|
|
3s74B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
K 3.1, 2.1
|
|
3hkqA
|
Human carbonic anhydrase ii in complex with 1-s-d-galactopyranosylsulfonamide
|
K 3.1, 2.1
|
|
2fnkA
|
Activation of human carbonic anhydrase ii by exogenous proton donors
|
K 3.1, 2.1
|
|
4iwzA
|
Structure of hcaii in complex with an acetazolamide derivative
|
K 3.1, 2.1
|
|
5ti0A
|
Crystal structure of 2-hydroxycyclohepta-2,4,6-triene-1-thione bound to human carbonic anhydrase 2 l198g
|
K 3.1, 2.1
|
|
5dsjA
|
Structure of co2 released holo-form of human carbonic anhydrase ii with 50 sec warming
|
K 3.1, 2.1
|
|
3sapA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-{[(5-butyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
K 3.1, 2.1
|
|
4q7vA
|
Crystal structure of 1-hydroxy-5-methylpyridine-2(1h)-thione bound to human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3s9tA
|
Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
K 3.1, 2.1
|
3
|
4r5aA
|
A carbonic anhydrase ix mimic in complex with a carbohydrate-based sulfamate
|
K 3.1, 2.1
|
|
4qjwA
|
Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with inhibitor
|
K 3.1, 2.1
|
|
5fnmA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
5jn7A
|
Carbonic anhydrase ii in complex with u-ch3
|
K 3.1, 2.1
|
|
4m2uA
|
Carbonic anhydrase ii in complex with dorzolamide
|
K 3.1, 2.1
|
|
3n2pA
|
Crystal structure of human carbonic anhydrase ii in complex with a benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
|
5ll9A
|
Crystal structure of human carbonic anhydrase isozyme xii with 4-(1h-benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide
|
K 3.1, 2.1
|
|
1g48A
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(2,6-difluorophenyl)methyl]-benzamide
|
K 3.1, 2.1
|
|
3m5tA
|
Fragment tethered to carbonic anhydrase ii h64c mutant
|
K 3.1, 2.1
|
|
1caiA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
1rayA
|
The structure of human carbonic anhydrase ii in complex with bromide and azide
|
K 3.1, 2.1
|
|
5fniA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
4yx4A
|
Human carbonic anhydrase ii complexed with an inhibitor with a benzenesulfonamide group (1).
|
K 3.1, 2.1
|
|
3t5zA
|
Crystal structure of the human carbonic anhydrase ii in complex with n-methoxy-benzenesulfonamide
|
K 3.1, 2.1
|
|
4zaoA
|
Genetically engineered carbonic anhydrase ix
|
K 3.1, 2.1
|
|
6b00A
|
Thermostabilized mutant of human carbonic anhydrase ii - a65t l100h k154n l224s l240p a248t
|
K 3.1, 2.1
|
|
5g0bA
|
An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of psammaplin c
|
K 3.1, 2.1
|
|
1eouA
|
Crystal structure of human carbonic anhydrase ii complexed with an anticonvulsant sugar sulfamate
|
K 3.1, 2.1
|
|
3oyqA
|
Structure of human carbonic anhydrase ii complexed with 5,6-dihydro-benzo[h]cinnolin-3-ylamine
|
K 3.1, 2.1
|
|
4lhiA
|
Crystal structure of human carbonic anhydrase isozyme ii with 5-(phenylsulfonyl)thiophene-2-sulfonamide
|
K 3.1, 2.1
|
|
5fl6A
|
Three dimensional structure of human carbonic anhydrase ix in complex with 5-(1-(4-methylphenyl)-1h-1,2,3-triazol-4-yl)thiophene-2- sulfonamide
|
K 3.1, 2.1
|
|
2pouA
|
The crystal structure of the human carbonic anhydrase ii in complex with 4,5-dichloro-benzene-1,3-disulfonamide
|
K 3.1, 2.1
|
|
5e2nA
|
Crystal structure of human carbonic anhydrase isozyme xiii with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
|
K 3.1, 2.1
|
|
5eh8A
|
Human carbonic anhydrase ii in complex with ligand
|
K 3.1, 2.1
|
|
1am6A
|
Carbonic anhydrase ii inhibitor: acetohydroxamate
|
K 3.1, 2.1
|
|
5amlA
|
Three dimensional structure of human carbonic anhydrase ii in complex with 2-(but-2-yn-1-ylsulfamoyl)-4-sulfamoylbenzoic acid
|
K 3.1, 2.1
|
|
1g53A
|
Carbonic anhydrase ii complexed with 4-(aminosulfonyl)-n-[(2,6-difluorophenyl)methyl]-benzamide
|
K 3.1, 2.1
|
|
4js6A
|
Crystal structure of inhibitor-free hcaii h94d
|
K 3.1, 2.1
|
|
4jssA
|
Human carbonic anhydrase ii h94d bound to a bidentate inhibitor
|
K 3.1, 2.1
|
|
1bntA
|
Carbonic anhydrase ii inhibitor
|
K 3.1, 2.1
|
|
1bzmA
|
Drug-protein interactions: structure of sulfonamide drug complexed with human carbonic anhydrase i
|
K 3.1, 2.1
|
|
4kp8A
|
Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with 3-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
|
K 3.1, 2.1
|
|
4heyA
|
Activity enhancers of h64a variant of human carbonic anhydrase ii possess multiple binding sites within and around the enzyme structure
|
K 3.1, 2.1
|
|
2vvaX
|
Human carbonic anhydrase in complex with co2
|
K 3.1, 2.1
|
|
5ehvA
|
Human carbonic anhydrase ii in complex with ligand
|
K 3.1, 2.1
|
|
1muaA
|
Structure and energetics of a non-proline cis-peptidyl linkage in an engineered protein
|
K 3.1, 2.1
|
|
4z1kA
|
Carbonic anhydrase inhibitors: design and synthesis of new heteroaryl-n-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hca vii, hca ix, and hca xiv)
|
K 3.1, 2.1
|
|
1g45A
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(2-fluorophenyl)methyl]-benzamide
|
K 3.1, 2.1
|
|
4q81A
|
Crystal structure of 1-hydroxy-4,6-dimethylpyridine-2(1h)-thione bound to human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
4dz7A
|
Hca ii in complex with novel sulfonamide inhibitors set d
|
K 3.1, 2.1
|
|
4knnA
|
Crystal structure of human carbonic anhydrase isozyme xiii with 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
|
K 3.1, 2.1
|
|
5e28A
|
Crystal structure of human carbonic anhydrase ii in complex with the 4-(4-aminophenyl)benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
|
5ll5A
|
Crystal structure of human carbonic anhydrase isozyme xii with 4-(1h-benzimidazol-1-ylacetyl)benzenesulfonamide
|
K 3.1, 2.1
|
|
5llaA
|
Crystal structure of human carbonic anhydrase isozyme xiii with 4-(1h-benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide
|
K 3.1, 2.1
|
|
5zxwA
|
Crystal structure of human carbonic anhydrase ii crystallized by ammonium sulfate
|
K 3.1, 2.1
|
|
5jqtA
|
Crystal structure of human carbonic anhydrase ii in complex with benzoxaborole at ph 7.4
|
K 3.1, 2.1
|
|
1camA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
6b4dA
|
Crystal structure of human carbonic anhydrase ii in complex with a heteroaryl-pyrazole carboxylic acid derivative.
|
K 3.1, 2.1
|
|
1cajA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
1rzeA
|
X-ray analysis of metal substituted human carbonic anhydrase ii derivatives
|
K 3.1, 2.1
|
|
1lzvA
|
Site-specific mutant (tyr7 replaced with his) of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
1teuX
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
1kwrA
|
Human carbonic anhydrase ii complexed with inhibitor 0134-36
|
K 3.1, 2.1
|
|
2powA
|
The crystal structure of the human carbonic anhydrase ii in complex with 4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide
|
K 3.1, 2.1
|
|
1tg3A
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3oy0A
|
Human carbonic anhydrase ii complexed with 1-(4-(4-(2-(isopropylsulfonyl)phenylamino)-1h-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol
|
K 3.1, 2.1
|
|
3p3hA
|
Human carbonic anhydrase ii in complex with p-(5-ferrocenyl-1h-1,2,3-triazol-1-yl)benzenesulfonamide
|
K 3.1, 2.1
|
|
3dvbA
|
X-ray crystal structure of mutant n62v human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3oimA
|
Human carbonic anhydrase ii bound by 2-ethylestradiol 3-o-sulfamate
|
K 3.1, 2.1
|
|
3rgeA
|
Crystal structure of the w5h mutant of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3rg4A
|
Crystal structure of the w5f mutant of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3rg3A
|
Crystal structure of the w5e mutant of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
4hezA
|
Activity enhancers of h64a variant of human carbonic anhydrase ii possess multiple binding sites within and around the enzyme structure
|
K 3.1, 2.1
|
|
4cacA
|
Refined structure of human carbonic anhydrase ii at 2.0 angstroms resolution
|
K 3.1, 2.1
|
|
4itpA
|
Structure of human carbonic anhydrase ii bound to a benzene sulfonamide
|
K 3.1, 2.1
|
|
4l5wA
|
Structural implications of the secondary co2 binding pocket in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
4q0lA
|
Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with inhibitor
|
K 3.1, 2.1
|
|
4rfdA
|
Human carbonic anhydrase ii in complex with 4-(4-sulfamoyl-phenoxy)-butylammonium
|
K 3.1, 2.1
|
|
3oysA
|
Human carbonic anhydrase ii complexed with 2-{[4-amino-3-(3-hydroxyprop-1-yn-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3h)-one
|
K 3.1, 2.1
|
|
4zx0A
|
Human carbonic anhydrase ii in complex with a glucosyl sulfamate inhibitor
|
K 3.1, 2.1
|
|
5ekmA
|
Human carbonic anhydrase ii complexed with a two-faced guest
|
K 3.1, 2.1
|
|
5c8iA
|
Joint x-ray/neutron structure of human carbonic anhydrase ii in complex with methazolamide
|
K 3.1, 2.1
|
|
5j8zA
|
Human carbonic anhydrase ii in complex with ligand
|
K 3.1, 2.1
|
|
5byiA
|
Human carbonic anhydrase ii with an azobenzene inhibitor (1d)
|
K 3.1, 2.1
|
|
5jegB
|
Human carbonic anhydrase ii (v121i) complexed with benzo[d]thiazole-2-sulfonamide
|
K 3.1, 2.1
|
|
5je7B
|
Human carbonic anhydrase ii (f131y) complexed with benzo[d]thiazole-2-sulfonamide
|
K 3.1, 2.1
|
|
5jg3B
|
Human carbonic anhydrase ii (121t/n67q) complexed with benzo[d]thiazole-2-sulfonamide
|
K 3.1, 2.1
|
|
5mjnA
|
Three dimensional structure of human carbonic anhydrase ii in complex with 5-[(4chlorobenzyl)sulfanyl]thiophene-2-sulfonamide
|
K 3.1, 2.1
|
|
5wg7A
|
Human carbonic anhydrase ii complexed with acek
|
K 3.1, 2.1
|
|
6bc9A
|
Joint x-ray/neutron structure of human carbonic anhydrase ii in complex with dorzolamide
|
K 3.1, 2.1
|
|
2hl4A
|
Crystal structure analysis of human carbonic anhydrase ii in complex with a benzenesulfonamide derivative
|
K 3.1, 2.1
|
|
3p5aA
|
Human carbonic anhydrase complexed with sodium morpholinocarbodithioate
|
K 3.1, 2.1
|
|
3p58A
|
Human carbonic anhydrase in complex with benzyl (methyl) carbamodithoic acid
|
K 3.1, 2.1
|
|
3mnhA
|
Human carbonic anhydrase ii mutant k170a
|
K 3.1, 2.1
|
|
2aw1A
|
Carbonic anhydrase inhibitors: valdecoxib binds to a different active site region of the human isoform ii as compared to the structurally related cyclooxygenase ii "selective" inhibitor celecoxib
|
K 3.1, 2.1
|
|
2hkkA
|
Carbonic anhydrase activators: solution and x-ray crystallography for the interaction of andrenaline with various carbonic anhydrase isoforms
|
K 3.1, 2.1
|
|
1i9lA
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(4-fluorophenyl)methyl]-benzamide
|
K 3.1, 2.1
|
|
1i9qA
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(3,4,5-trifluorophenyl)methyl]-benzamide
|
K 3.1, 2.1
|
|
3dccA
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
K 3.1, 2.1
|
|
4cq0A
|
Cyclic secondary sulfonamides: unusually good inhibitors of cancer- related carbonic anhydrase enzymes
|
K 3.1, 2.1
|
|
3kwaA
|
Polyamines inhibit carbonic anhydrases
|
K 3.1, 2.1
|
|
4xiwA
|
Carbonic anhydrase cah3 from chlamydomonas reinhardtii in complex with acetazolamide
|