2OBVA

Crystal structure of the human s-adenosylmethionine synthetase 1 in complex with the product
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 19-271 253 1-18, 272-384 18 113 knot
Chain Sequence
FQSMGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 23-284 262 1-8, 312-384 9-22, 285-311 8 73 slipknot
view details
2.1 23-311 289 1-8, 355-384 9-22, 312-354 8 30 slipknot
view details
2.1 24-295 272 1-22, 350-384 23-23, 296-349 22 35 slipknot
sequence length 384
structure length 384
publication title Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product.
rcsb
molecule tags Transferase
molecule keywords S-adenosylmethionine synthetase isoform type-1
source organism Homo sapiens
total genus Genus: 139
ec nomenclature ec 2.5.1.6: Methionine adenosyltransferase.
pdb deposition date 2006-12-20
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00438 S-AdoMet_synt_N S-adenosylmethionine synthetase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.300.10 Alpha Beta 2-Layer Sandwich GMP Synthetase; Chain A, domain 3 GMP Synthetase; Chain A, domain 3 2obvA03
3.30.300.10 Alpha Beta 2-Layer Sandwich GMP Synthetase; Chain A, domain 3 GMP Synthetase; Chain A, domain 3 2obvA01
3.30.300.10 Alpha Beta 2-Layer Sandwich GMP Synthetase; Chain A, domain 3 GMP Synthetase; Chain A, domain 3 2obvA02
1O92A 1XRBA 1MXCA 3IMLA 1O90A 1O93A 1FUGA 1O9TA 1MXBA 1P7LA 1QM4A 1XRAA 1XRCA 1MXAA 2OBVA 2P02A 1RG9A
chains in the KnotProt database with same CATH superfamily
1O92A 1XRBA 1MXCA 3IMLA 1O90A 1O93A 1FUGA 1O9TA 1MXBA 1P7LA 1QM4A 1XRAA 1XRCA 1MXAA 2OBVA 2P02A 1RG9A
chains in the KnotProt database with same CATH topology
1O92A 1XRBA 1MXCA 3IMLA 1O90A 1O93A 1FUGA 1O9TA 1MXBA 1P7LA 1QM4A 1XRAA 1XRCA 1MXAA 2OBVA 2P02A 1RG9A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1O92 A;  1XRB A;  1MXC A;  3IML A;  1O90 A;  1O93 A;  1FUG A;  1O9T A;  1MXB A;  1P7L A;  1QM4 A;  1XRA A;  1XRC A;  1MXA A;  2OBV A;  2P02 A;  1RG9 A; 
#chains in the KnotProt database with same CATH topology
 1O92 A;  1XRB A;  1MXC A;  3IML A;  1O90 A;  1O93 A;  1FUG A;  1O9T A;  1MXB A;  1P7L A;  1QM4 A;  1XRA A;  1XRC A;  1MXA A;  2OBV A;  2P02 A;  1RG9 A; 
#chains in the KnotProt database with same CATH homology
 1O92 A;  1XRB A;  1MXC A;  3IML A;  1O90 A;  1O93 A;  1FUG A;  1O9T A;  1MXB A;  1P7L A;  1QM4 A;  1XRA A;  1XRC A;  1MXA A;  2OBV A;  2P02 A;  1RG9 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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