2OBVA

Crystal structure of the human s-adenosylmethionine synthetase 1 in complex with the product
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 19-271 253 1-18, 272-384 18 113 knot
Chain Sequence
FQSMGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 23-284 262 1-8, 312-384 9-22, 285-311 8 73 slipknot
view details
2.1 23-311 289 1-8, 355-384 9-22, 312-354 8 30 slipknot
view details
2.1 24-295 272 1-22, 350-384 23-23, 296-349 22 35 slipknot
sequence length 384
structure length 384
publication title Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product.
rcsb
molecule tags Transferase
molecule keywords S-adenosylmethionine synthetase isoform type-1
source organism Homo sapiens
total genus Genus: 139
ec nomenclature ec 2.5.1.6: Methionine adenosyltransferase.
pdb deposition date 2006-12-20
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00438 S-AdoMet_synt_N S-adenosylmethionine synthetase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.300.10 Alpha Beta 2-Layer Sandwich GMP Synthetase; Chain A, domain 3 GMP Synthetase; Chain A, domain 3 2obvA03
3.30.300.10 Alpha Beta 2-Layer Sandwich GMP Synthetase; Chain A, domain 3 GMP Synthetase; Chain A, domain 3 2obvA01
3.30.300.10 Alpha Beta 2-Layer Sandwich GMP Synthetase; Chain A, domain 3 GMP Synthetase; Chain A, domain 3 2obvA02
2OBVA 1O9TA 1RG9A 2P02A 1O92A 3IMLA 1O90A 1MXCA 1O93A 1P7LA 1MXBA 1MXAA 1QM4A 1FUGA 1XRAA 1XRBA 1XRCA
chains in the KnotProt database with same CATH superfamily
2OBVA 1O9TA 1RG9A 2P02A 1O92A 3IMLA 1O90A 1MXCA 1O93A 1P7LA 1MXBA 1MXAA 1QM4A 1FUGA 1XRAA 1XRBA 1XRCA
chains in the KnotProt database with same CATH topology
2OBVA 1O9TA 1RG9A 2P02A 1O92A 3IMLA 1O90A 1MXCA 1O93A 1P7LA 1MXBA 1MXAA 1QM4A 1FUGA 1XRAA 1XRBA 1XRCA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 2OBV A;  1O9T A;  1RG9 A;  2P02 A;  1O92 A;  3IML A;  1O90 A;  1MXC A;  1O93 A;  1P7L A;  1MXB A;  1MXA A;  1QM4 A;  1FUG A;  1XRA A;  1XRB A;  1XRC A; 
#chains in the KnotProt database with same CATH topology
 2OBV A;  1O9T A;  1RG9 A;  2P02 A;  1O92 A;  3IML A;  1O90 A;  1MXC A;  1O93 A;  1P7L A;  1MXB A;  1MXA A;  1QM4 A;  1FUG A;  1XRA A;  1XRB A;  1XRC A; 
#chains in the KnotProt database with same CATH homology
 2OBV A;  1O9T A;  1RG9 A;  2P02 A;  1O92 A;  3IML A;  1O90 A;  1MXC A;  1O93 A;  1P7L A;  1MXB A;  1MXA A;  1QM4 A;  1FUG A;  1XRA A;  1XRB A;  1XRC A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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