Found 152 chains in Knotted chains table. Displaying 1 - 150. Applied filters: Probabilistic

Search results query: topological notation: K +31 3x +31

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#pdbid|chain|deposition date|is S/K-not|(slip)knot types;
      
  6eda|A|2018-12-02|K|+3.1;
  6eea|A|2018-12-02|K|+3.1;
  3iqk|A|2018-10-21|K|+3.1;
  5fl5|A|2018-10-21|K|+3.1;
  1cak|A|2018-10-21|K|+3.1;
  4qk1|A|2018-10-20|K|+3.1;
  5flo|A|2018-10-20|K|+3.1;
  5th4|A|2018-10-20|K|+3.1;
  5cjf|A|2018-10-20|K|+3.1;
  1z97|A|2018-10-20|K|+3.1;
  5sz5|A|2018-10-20|K|+3.1;
  1fsq|A|2018-10-20|K|+3.1;
  3ryj|B|2018-10-20|K|+3.1;
  4ygn|A|2018-10-20|K|+3.1;
  5lmd|A|2018-10-20|K|+3.1;
  5jgs|B|2018-10-20|K|+3.1;
  4mlt|A|2018-10-20|K|+3.1;
  5eij|A|2018-10-20|K|+3.1;
  4r59|A|2018-10-20|K|+3.1;
  4mdg|A|2018-10-20|K|+3.1;
  3mnu|A|2018-10-20|K|+3.1;
  2nno|A|2018-10-20|K|+3.1;
  1cao|A|2018-10-20|K|+3.1;
  3v2j|A|2018-10-20|K|+3.1;
  3kon|A|2018-10-20|K|+3.1;
  4m2r|A|2018-10-20|K|+3.1;
  2nwo|A|2018-10-20|K|+3.1;
  5msa|A|2018-10-20|K|+3.1;
  5flp|A|2018-10-20|K|+3.1;
  5flr|A|2018-10-20|K|+3.1;
  4xz5|A|2018-10-20|K|+3.1;
  4qsb|A|2018-10-20|K|+3.1;
  5ty1|A|2018-10-20|K|+3.1;
  3mhc|A|2018-10-20|K|+3.1;
  5fls|A|2018-10-20|K|+3.1;
  5umc|A|2018-10-20|K|+3.1;
  5tt3|A|2018-10-20|K|+3.1;
  5g01|A|2018-10-20|K|+3.1;
  4ywp|A|2018-10-20|K|+3.1;
  3s72|B|2018-10-20|K|+3.1;
  3daz|A|2018-10-20|K|+3.1;
  2vvb|X|2018-10-20|K|+3.1;
  4z1e|A|2018-10-20|K|+3.1;
  3kkx|A|2018-10-20|K|+3.1;
  4kp5|A|2018-10-20|K|+3.1;
  4l5v|A|2018-10-20|K|+3.1;
  3u3a|X|2018-10-20|K|+3.1;
  3hkn|A|2018-10-20|K|+3.1;
  5tfx|A|2018-10-20|K|+3.1;
  2fnn|A|2018-10-20|K|+3.1;
  1ugd|A|2018-10-20|K|+3.1;
  3p3j|A|2018-10-20|K|+3.1;
  5jes|B|2018-10-20|K|+3.1;
  3gz0|A|2018-10-20|K|+3.1;
  4kp8|A|2018-10-19|K|+3.1;
  4z1k|A|2018-10-19|K|+3.1;
  2pou|A|2018-10-19|K|+3.1;
  6b00|A|2018-10-19|K|+3.1;
  5u0e|A|2018-10-19|K|+3.1;
  5g0b|A|2018-10-19|K|+3.1;
  5ll9|A|2018-10-19|K|+3.1;
  4m2u|A|2018-10-19|K|+3.1;
  4r5a|A|2018-10-19|K|+3.1;
  2fnk|A|2018-10-19|K|+3.1;
  5fnm|A|2018-10-19|K|+3.1;
  4iwz|A|2018-10-19|K|+3.1;
  4ht2|A|2018-10-19|K|+3.1;
  3s74|B|2018-10-19|K|+3.1;
  3v7x|A|2018-10-19|K|+3.1;
  3dv7|A|2018-10-19|K|+3.1;
  4qjm|A|2018-10-19|K|+3.1;
  6bbs|A|2018-10-19|K|+3.1;
  4mdm|A|2018-10-19|K|+3.1;
  3n0n|A|2018-10-19|K|+3.1;
  4fl7|A|2018-10-19|K|+3.1;
  2wd3|A|2018-10-19|K|+3.1;
  4e5q|A|2018-10-19|K|+3.1;
  4wl4|A|2018-10-19|K|+3.1;
  5u0f|A|2018-10-19|K|+3.1;
  4kuy|A|2018-10-19|K|+3.1;
  3v2m|A|2018-10-19|K|+3.1;
  5tya|A|2018-10-19|K|+3.1;
  4pyx|A|2018-10-19|K|+3.1;
  6fe1|A|2018-10-19|K|+3.1;
  3ryx|B|2018-10-19|K|+3.1;
  1raz|A|2018-10-19|K|+3.1;
  4e4a|A|2018-10-19|K|+3.1;
  2fnm|A|2018-10-19|K|+3.1;
  3r16|A|2018-10-19|K|+3.1;
  5wlr|A|2018-10-19|K|+3.1;
  6d1l|A|2018-10-19|K|+3.1;
  3vbd|A|2018-10-19|K|+3.1;
  5jeh|B|2018-10-19|K|+3.1;
  4q90|A|2018-10-19|K|+3.1;
  2nns|A|2018-10-19|K|+3.1;
  3myq|A|2018-10-19|K|+3.1;
  3m1q|A|2018-10-19|K|+3.1;
  5tuo|A|2018-10-19|K|+3.1;
  4e3f|A|2018-10-19|K|+3.1;
  3p55|A|2018-10-18|K|+3.1;
  2nwz|A|2018-10-18|K|+3.1;
  3uyn|A|2018-10-18|K|+3.1;
  5t71|A|2018-10-18|K|+3.1;
  3ml2|A|2018-10-18|K|+3.1;
  4k1q|A|2018-10-18|K|+3.1;
  5ty8|A|2018-10-18|K|+3.1;
  5g0c|A|2018-10-18|K|+3.1;
  1fsr|A|2018-10-18|K|+3.1;
  6g98|A|2018-10-18|K|+3.1;
  5dvx|A|2018-10-18|K|+3.1;
  5amd|A|2018-10-18|K|+3.1;
  4qef|A|2018-10-18|K|+3.1;
  4hew|A|2018-10-18|K|+3.1;
  3oku|A|2018-10-18|K|+3.1;
  1z93|A|2018-10-18|K|+3.1;
  5brw|A|2018-10-18|K|+3.1;
  5wex|A|2018-10-18|K|+3.1;
  4q06|A|2018-10-18|K|+3.1;
  3p5a|A|2018-10-18|K|+3.1;
  5je7|B|2018-10-18|K|+3.1;
  5ekm|A|2018-10-18|K|+3.1;
  4z1j|A|2018-10-18|K|+3.1;
  2wej|A|2018-10-18|K|+3.1;
  3oys|A|2018-10-18|K|+3.1;
  4itp|A|2018-10-18|K|+3.1;
  3dvb|A|2018-10-18|K|+3.1;
  2pow|A|2018-10-18|K|+3.1;
  4e3g|A|2018-10-18|K|+3.1;
  2ili|A|2018-10-18|K|+3.1;
  4fik|A|2018-10-18|K|+3.1;
  4knn|A|2018-10-17|K|+3.1;
  3sax|A|2018-10-17|K|+3.1;
  4qsa|A|2018-10-17|K|+3.1;
  3s8x|A|2018-10-17|K|+3.1;
  6got|A|2018-10-13|K|+3.1;
  3s73|B|2018-10-04|K|+3.1;
  4lu3|A|2018-10-03|K|+3.1;
  5yuj|A|2018-10-03|K|+3.1;
  2osf|A|2018-10-03|K|+3.1;
  4kap|A|2018-10-03|K|+3.1;
  3rz0|B|2018-10-02|K|+3.1;
  3t85|A|2018-10-02|K|+3.1;
  3czv|A|2018-10-01|K|+3.1;
  3okv|A|2018-10-01|K|+3.1;
  3sbi|A|2018-10-01|K|+3.1;
  3bl0|A|2018-10-01|K|+3.1;
  2fos|A|2018-09-29|K|+3.1;
  1xev|A|2018-09-28|K|+3.1;
  2nxt|A|2018-09-28|K|+3.1;
  5gmn|A|2018-09-26|K|+3.1;
  2ax2|A|2018-09-26|K|+3.1;
  5l70|A|2018-09-26|K|+3.1;

      
Knot types Knot loop types pdb Title
K +31 K 3x +31 6edaA Bioreductive 4-hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms ix and xii and show hypoxia-enhanced cytotoxicity against human cancer cell lines.
K +31 K 3x +31 6eeaA Bioreductive 4-hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms ix and xii and show hypoxia-enhanced cytotoxicity against human cancer cell lines.
K +31 K 3x +31 3iqkA Human carbonic anhydrase ii h64a complexed with thioxolone hydrolysis products
K +31 K 3x +31 5fl5A Three dimensional structure of human carbonic anhydrase ix in complex with 5-(1-(4-methoxyphenyl)-1h-1,2,3-triazol-4-yl)thiophene-2- sulfonamide
K +31 K 3x +31 1cakA Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
K +31 K 3x +31 4qk1A Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase ii - k170p
K +31 K 3x +31 5floA Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
K +31 K 3x +31 5th4A Crystal structure of 1-hydroxypyridine-2(1h)-thione bound to human carbonic anhydrase 2 l198g
K +31 K 3x +31 5cjfA The crystal structure of the human carbonic anhydrase xiv in complex with a 1,1'-biphenyl-4-sulfonamide inhibitor.
K +31 K 3x +31 1z97A Human carbonic anhydrase iii: structural and kinetic study of catalysis and proton transfer.
K +31 K 3x +31 5sz5A Carbonic anhydrase ix-mimic in complex with 4-(2-methylphenyl)-benzenesulfonamide
K +31 K 3x +31 1fsqA X-ray crystal structure of cobalt-bound f93s/f95l/w97m carbonic anhydrase (caii) variant
K +31 K 3x +31 3ryjB Carbonic anhydrase complexed with 4-sulfamoyl-n-(2,2,2-trifluoroethyl)benzamide
K +31 K 3x +31 4ygnA Nai--interactions between hofmeister anions and the binding pocket of a protein
K +31 K 3x +31 5lmdA The crystal structure of hca ii in complex with a benzoxaborole inhibitor
K +31 K 3x +31
4
5jgsB Human carbonic anhydrase ii (f131y/l198a) complexed with benzo[d]thiazole-2-sulfonamide
K +31 K 3x +31 4mltA Structure of a monodentate 3-hydroxy-4h-pyran-4-thione ligand bound to hcaii
K +31 K 3x +31 5eijA Carbonic anhydrase ii in complex with sulfonamide inhibitor
K +31 K 3x +31 4r59A A carbonic anhydrase ix mimic in complex with a carbohydrate-based sulfamate
K +31 K 3x +31 4mdgA Closo carborane carbonic anhydrase inhibitor
K +31 K 3x +31 3mnuA Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron containing aromatic sulfamide with mammalian isoforms i-xv
K +31 K 3x +31
4
2nnoA Structure of inhibitor binding to carbonic anhydrase ii
K +31 K 3x +31 1caoA Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions
K +31 K 3x +31 3v2jA Effect of sucrose and glycerol as cryoprotectans, on the inhibition of human carbonic anhydrase ii
K +31 K 3x +31 3konA Crystal structure of cobalt (ii) human carbonic anhydrase ii at ph 11.0
K +31 K 3x +31 4m2rA Human carbonic anhydrase ii in complex with brinzolamide
K +31 K 3x +31 2nwoA Structural and kinetic effect of hydrophobic mutations in the active site of human carbonic anhydrase ii
K +31 K 3x +31 5msaA Crystal structure of human carbonic anhydrase isozyme xii with 2,3,5,6-tetrafluoro-4-(propylthio)benzenesulfonamide
K +31 K 3x +31 5flpA Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
K +31 K 3x +31 5flrA Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
K +31 K 3x +31 4xz5A Structure of the thermostable alpha-carbonic anydrase from thiomicrospira crunogena xcl-2 gammaproteobacterium
K +31 K 3x +31 4qsbA Crystal structure of human carbonic anhydrase isozyme ii with 3-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide
K +31 K 3x +31 5ty1A Identification of a new zinc binding chemotype by fragment screening
K +31 K 3x +31 3mhcA Crystal structure of human cabonic anhydrase ii in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket
K +31 K 3x +31 5flsA Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
K +31 K 3x +31 5umcA Synthesis of novel seleno ureido containing compounds as slc-0111 analogs. investigations on carbonic anhydrases activity, glutathione peroxidase and x-ray crystallography
K +31 K 3x +31
4
5tt3A Crystal structure of the complex of helicobacter pylori alpha-carbonic anhydrase with ethoxzolamide
K +31 K 3x +31 5g01A An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of psammaplin c
K +31 K 3x +31 4ywpA Sucrose binding site in genetically engineered carbonic anhydrase ix
K +31 K 3x +31
4
3s72B The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
K +31 K 3x +31 3dazA Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
K +31 K 3x +31 2vvbX Human carbonic anhydrase ii in complex with bicarbonate
K +31 K 3x +31 4z1eA Carbonic anhydrase inhibitors: design and synthesis of new heteroaryl-n-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hca vii, hca ix, and hca xiv)
K +31 K 3x +31 3kkxA Neutron structure of human carbonic anhydrase ii
K +31 K 3x +31 4kp5A Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
K +31 K 3x +31 4l5vA The structural implications of the secondary co2 binding pocket in human carbonic anhydrase ii
K +31 K 3x +31 3u3aX Structure of human carbonic anhydrase ii v143i
K +31 K 3x +31 3hknA Human carbonic anhydrase ii in complex with (2,3,4,6-tetra-o-acetyl-beta-d-galactopyranosyl) -(1-4)-1,2,3,6-tetra-o-acetyl-1-thio-beta-d-glucopyranosylsulfonamide
K +31 K 3x +31 5tfxA New method for synthesis of benzoxazole amide inhibitors of carbonic anhydrase
K +31 K 3x +31 2fnnA Activation of human carbonic anhydrase ii by exogenous proton donors
K +31 K 3x +31 1ugdA Human carbonic anhydrase ii[hcaii] (e.c.4.2.1.1) mutant with ala 65 replaced by ser (a65s)
K +31 K 3x +31 3p3jA Human carbonic anhydrase ii in complex with p-(5-ruthenocenyl-1h-1,2,3-triazol-1-yl)benzenesulfonamide
K +31 K 3x +31 5jesB Human carbonic anhydrase ii (v121t) complexed with benzo[d]thiazole-2-sulfonamide
K +31 K 3x +31 3gz0A Apo-human carbonic anhydrase ii revisited: implications of the loss of a metal in protein structure, stability and solvent network
K +31 K 3x +31 4kp8A Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with 3-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
K +31 K 3x +31 4z1kA Carbonic anhydrase inhibitors: design and synthesis of new heteroaryl-n-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hca vii, hca ix, and hca xiv)
K +31 K 3x +31 2pouA The crystal structure of the human carbonic anhydrase ii in complex with 4,5-dichloro-benzene-1,3-disulfonamide
K +31 K 3x +31 6b00A Thermostabilized mutant of human carbonic anhydrase ii - a65t l100h k154n l224s l240p a248t
K +31 K 3x +31 5u0eA Identification of a new zinc binding chemotype by fragment screening
K +31 K 3x +31 5g0bA An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of psammaplin c
K +31 K 3x +31 5ll9A Crystal structure of human carbonic anhydrase isozyme xii with 4-(1h-benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide
K +31 K 3x +31 4m2uA Carbonic anhydrase ii in complex with dorzolamide
K +31 K 3x +31
4
4r5aA A carbonic anhydrase ix mimic in complex with a carbohydrate-based sulfamate
K +31 K 3x +31 2fnkA Activation of human carbonic anhydrase ii by exogenous proton donors
K +31 K 3x +31 5fnmA Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
K +31 K 3x +31 4iwzA Structure of hcaii in complex with an acetazolamide derivative
K +31 K 3x +31 4ht2A Crystal structure of human carbonic anhydrase isozyme xii with the inhibitor.
K +31 K 3x +31 3s74B The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
K +31 K 3x +31 3v7xA Complex of human carbonic anhydrase ii with n-[2-(3,4-dimethoxyphenyl)ethyl]-4-sulfamoylbenzamide
K +31 K 3x +31 3dv7A Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase ii (n62a)
K +31 K 3x +31 4qjmA Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
K +31 K 3x +31 6bbsA Joint x-ray/neutron structure of human carbonic anhydrase ii in complex with brinzolamide
K +31 K 3x +31 4mdmA Nido-carborane carbonic anhydrase inhibitor
K +31 K 3x +31 3n0nA Crystal structure of human carbonic anhydrase ii in complex with a benzenesulfonamide inhibitor
K +31 K 3x +31 4fl7A The crystal structure of human carbonic anhydrase ii in complex with n-(hydroxy)-benzamide
K +31 K 3x +31 2wd3A Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template
K +31 K 3x +31 4e5qA Human carbonic anhydrase ii in complex with cyanate
K +31 K 3x +31 4wl4A Crystal structure of human carbonic anhydrase ii in complex with the 6-hydroxy-chromene-2-thione inhibitor
K +31 K 3x +31 5u0fA Identification of a new zinc binding chemotype by fragment screening
K +31 K 3x +31 4kuyA Crystal structure of human carbonic anhydrase ii in complex with the 5-(3-(o-tolylsulfonyl)ureido)pyridine-2-sulfonamide inhibitor
K +31 K 3x +31 3v2mA Effect of sucrose and glycerol as cryoprotectans, on the inhibition of human carbonic anhydrase ii
K +31 K 3x +31 5tyaA Identification of a new zinc binding chemotype by fragment screening
K +31 K 3x +31 4pyxA Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
K +31 K 3x +31 6fe1A Three dimensional structure of human carbonic anhydrase ix in complex with benzenesulfonamide.
K +31 K 3x +31 3ryxB Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the hydrophobic wall of carbonic anhydrase
K +31 K 3x +31 1razA The structure of human carbonic anhydrase ii in complex with bromide and azide
K +31 K 3x +31 4e4aA Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
K +31 K 3x +31 2fnmA Activation of human carbonic anhdyrase ii by exogenous proton donors
K +31 K 3x +31 3r16A Human caii bound to n-(4-sulfamoylphenyl)-2-(thiophen-2-yl) acetamide
K +31 K 3x +31 5wlrA Carbonic anhydrase ix-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
K +31 K 3x +31 6d1lA Design, synthesis, and x-ray of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects
K +31 K 3x +31 3vbdA Complex of human carbonic anhydrase ii with 4-(6-methoxy-3,4-dihydroisoquinolin-1-yl)benzenesulfonamide
K +31 K 3x +31 5jehB Human carbonic anhydrase ii (l198a) complexed with benzo[d]thiazole-2-sulfonamide
K +31 K 3x +31 4q90A Crystal structure of 4-methylpyridine-2(1h)-thione bound to human carbonic anhydrase ii
K +31 K 3x +31
4
2nnsA Structure of inhibitor binding to carbonic anhydrase ii
K +31 K 3x +31 3myqA Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-5-[(1h-imidazo[4,5-c]quinolin-2-ylsulfanyl)acetyl]benzenesulfonamide
K +31 K 3x +31 3m1qA Carbonic anhydrase ii mutant w5c-h64c with opened disulfide bond
K +31 K 3x +31
4
5tuoA Crystal structure of the complex of helicobacter pylori alpha-carbonic anhydrase with 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.
K +31 K 3x +31 4e3fA Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
K +31 K 3x +31 3p55A Human carbonic anhydrase ii in complex with p-(4-ferrocenyl-1h-1,2,3-triazol-1-yl)benzenesulfonamide
K +31 K 3x +31 2nwzA Structural and kinetic effects of hydrophobic mutations on the active site of human carbonic anhydrase ii
K +31 K 3x +31 3uynA Hca 3
K +31 K 3x +31 5t71A Human carboanhydrase f131c_c206s double mutant in complex with sa-2
K +31 K 3x +31 3ml2A Human carbonic anhydsase ii in complex with an aryl sulfonamide inhibitor
K +31 K 3x +31 4k1qA Structure of hcaix mimic (hcaii with 5 mutations in active site)
K +31 K 3x +31 5ty8A Identification of a new zinc binding chemotype by fragment screening
K +31 K 3x +31 5g0cA An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of psammaplin c
K +31 K 3x +31 1fsrA X-ray crystal structure of copper-bound f93s/f95l/w97m carbonic anhydrase (caii) variant
K +31 K 3x +31 6g98A Three dimensional structure of human carbonic anhydrase ix in complex with sulfonamide
K +31 K 3x +31 5dvxA Crystal structure of the catalytic-domain of human carbonic anhydrase ix at 1.6 angstrom resolution
K +31 K 3x +31 5amdA Three dimensional structure of human carbonic anhydrase ii in complex with 2-((2-phenylethyl)sulfamoyl)-4-sulfamoylbenzoic acid
K +31 K 3x +31 4qefA Human carbonic anhydrase ii v207i - cyanate inhibitor complex
K +31 K 3x +31 4hewA Activity enhancers of h64a variant of human carbonic anhydrase ii possess multiple binding sites within and around the enzyme structure
K +31 K 3x +31 3okuA Human carbonic anhydrase ii in complex with 2-ethylestrone-3-o-sulfamate
K +31 K 3x +31 1z93A Human carbonic anhydrase iii:structural and kinetic study of catalysis and proton transfer.
K +31 K 3x +31 5brwA Catalytic improvement of an artificial metalloenzyme by computational design
K +31 K 3x +31 5wexA Discovery of new selenoureido analogs of 4-(4-fluorophenylureido) benzenesulfonamides as carbonic anhydrase inhibitors
K +31 K 3x +31 4q06A Crystal structure of chimeric carbonic anhydrase ix with inhibitor
K +31 K 3x +31 3p5aA Human carbonic anhydrase complexed with sodium morpholinocarbodithioate
K +31 K 3x +31 5je7B Human carbonic anhydrase ii (f131y) complexed with benzo[d]thiazole-2-sulfonamide
K +31 K 3x +31 5ekmA Human carbonic anhydrase ii complexed with a two-faced guest
K +31 K 3x +31 4z1jA Carbonic anhydrase inhibitors: design and synthesis of new heteroaryl-n-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hca vii, hca ix, and hca xiv)
K +31 K 3x +31 2wejA Thermodynamic optimisation of carbonic anhydrase fragment inhibitors
K +31 K 3x +31 3oysA Human carbonic anhydrase ii complexed with 2-{[4-amino-3-(3-hydroxyprop-1-yn-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3h)-one
K +31 K 3x +31 4itpA Structure of human carbonic anhydrase ii bound to a benzene sulfonamide
K +31 K 3x +31 3dvbA X-ray crystal structure of mutant n62v human carbonic anhydrase ii
K +31 K 3x +31 2powA The crystal structure of the human carbonic anhydrase ii in complex with 4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide
K +31 K 3x +31 4e3gA Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
K +31 K 3x +31 2iliA Refine atomic structure of human carbonic anhydrase ii
K +31 K 3x +31 4fikA Human carbonic anhydrase ii h64a complexed with thioxolone hydrolysis products
K +31 K 3x +31 4knnA Crystal structure of human carbonic anhydrase isozyme xiii with 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
K +31 K 3x +31 3saxA Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-5-{[(5-ethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
K +31 K 3x +31 4qsaA Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide
K +31 K 3x +31 3s8xA Crystal structure of human carbonic anhydrase isozyme ii with 4-{[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
K +31 K 3x +31 6gotA Crystal structure of human carbonic anhydrase ii in complex with the inhibitor 4-(phenethylthio)benzenesulfonamide
K +31 K 3x +31 3s73B The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
K +31 K 3x +31 4lu3A The crystal structure of the human carbonic anhydrase xiv
K +31 K 3x +31 5yujA Co2 release in human carbonic anhydrase ii crystals: reveal histidine 64 and solvent dynamics
K +31 K 3x +31 2osfA Inhibition of carbonic anhydrase ii by thioxolone: a mechanistic and structural study
K +31 K 3x +31 4kapA The binding of benzoarylsulfonamide ligands to human carbonic anhydrase is insensitive to formal fluorination of the ligand
K +31 K 3x +31 3rz0B Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the hydrophobic wall of carbonic anhydrase
K +31 K 3x +31 3t85A Human carbonic anhydrase ii in complex with acetylated carbohydrate sulfamates
K +31 K 3x +31 3czvA Crystal structure of the human carbonic anhydrase xiii in complex with acetazolamide
K +31 K 3x +31 3okvA Human carbonic anhydrase ii a65s, n67q (ca ix mimic) bound with 2-ethylestrone 3-o-sulfamate
K +31 K 3x +31 3sbiA Crystal structure of human carbonic anhydrase isozyme ii with 4-[(2-pyrimidinylsulfanyl)acetyl]benzenesulfonamide
K +31 K 3x +31 3bl0A Carbonic anhydrase inhibitors. interaction of 2-n,n-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with twelve mammalian isoforms: kinetic and x-ray crystallographic studies
K +31 K 3x +31
4
2fosA Human carbonic anhydrase ii complexed with two-prong inhibitors
K +31 K 3x +31 1xevA Crystal structure of human carbonic anhydrase ii in a new crystal form
K +31 K 3x +31 2nxtA Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase ii
K +31 K 3x +31 5gmnA Crystal structure of human carbonic anhydrase ii in complex with polmacoxib

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