S +31
|
S 3x +31
|
|
5eh5A
|
Human carbonic anhydrase ii in complex with ligand
|
S +31
|
S 3x +31
|
|
4rn4A
|
Human carbonic anhydrases ii in complex with a acetazolamide derivative comprising one hydrophobic and one hydrophilic tail moiety
|
S +31
|
S 3x +31
|
|
4pq7A
|
The crystal structure of the human carbonic anhydrase ii in complex with a sulfamide inhibitor
|
S +31
|
S 3x +31
|
|
3hljA
|
Crystal structure of human carbonic anhydrase isozyme ii with 3-methylthiobenzimidazo[1,2-c][1,2,3]thiadiazol-7-sulfonamide
|
S +31
|
S 3x +31
|
|
3oikA
|
Human carbonic anhydrase ii mutant a65s, n67q (ca ix mimic) bound by 2-ethylestradiol 3,17-o,o-bis-sulfamate
|
S +31
|
S 3x +31
|
|
3mnjA
|
Human carbonic anhydrase ii mutant k170e
|
S +31
|
S 3x +31
|
4
|
2x7sA
|
Structures of human carbonic anhydrase ii inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors.
|
S +31
|
S 3x +31
|
|
1hcbA
|
Enzyme-substrate interactions: structure of human carbonic anhydrase i complexed with bicarbonate
|
S +31
|
S 3x +31
|
|
3mniA
|
Human carbonic anhydrase ii mutant k170d
|
S +31
|
S 3x +31
|
4
|
2nngA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
6b5aA
|
Carbonic anhydrase ix-mimic in complex with nitrogenous base-bearing benezenesulfonamide
|
S +31
|
S 3x +31
|
|
3w6iA
|
Crystal structure of 19f probe-labeled hcai
|
S +31
|
S 3x +31
|
4
|
2foqA
|
Human carbonic anhydrase ii complexed with two-prong inhibitors
|
S +31
|
S 3x +31
|
|
5bu6B
|
Structure of bpsb deaceylase domain from bordetella bronchiseptica
|
S +31
|
S 3x +31
|
|
4q49A
|
Room temperature neutron crystal structure of apo human carbonic anhydrase at ph 7.5
|
S +31
|
S 3x +31
|
|
1yo0A
|
Proton transfer from his200 in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
4zwzA
|
Engineered carbonic anhydrase ix mimic in complex with a glucosyl sulfamate inhibitor
|
S +31
|
S 3x +31
|
|
3ryvB
|
Carbonic anhydrase complexed with n-ethyl-4-sulfamoylbenzamide
|
S +31
|
S 3x +31
|
|
4g7aA
|
The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium sulfurihydrogenibium yellowstonense yo3aop1
|
S +31
|
S 3x +31
|
|
5txyA
|
Identification of a new zinc binding chemotype of by fragment screening on human carbonic anhydrase
|
S +31
|
S 3x +31
|
|
1te3X
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
4k13A
|
Structure of hcaix mimic (hcaii with 5 mutations in active site) in complex with dorzolamide
|
S +31
|
S 3x +31
|
|
1hugA
|
Differences in anionic inhibition of human carbonic anhydrase i revealed from the structures of iodide and gold cyanide inhibitor complexes
|
S +31
|
S 3x +31
|
|
3rz1B
|
Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the hydrophobic wall of carbonic anhydrase
|
S +31
|
S 3x +31
|
4
|
3fe4A
|
Crystal structure of human carbonic anhydrase vi
|
S +31
|
S 3x +31
|
|
3bl1A
|
Carbonic anhydrase inhibitors. sulfonamide diuretics revisited old leads for new applications
|
S +31
|
S 3x +31
|
|
3p44A
|
Human carbonic anhydrase ii in complex with p-(4-ruthenocenyl-1h-1,2,3-triazol-1-yl)benzenesulfonamide
|
S +31
|
S 3x +31
|
|
4z1nA
|
Carbonic anhydrase inhibitors: design and synthesis of new heteroaryl-n-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hca vii, hca ix, and hca xiv)
|
S +31
|
S 3x +31
|
|
1lgdA
|
Crystal structure analysis of hca ii mutant t199p in complex with bicarbonate
|
S +31
|
S 3x +31
|
|
1huhA
|
Differences in anionic inhibition of human carbonic anhydrase i revealed from the structures of iodide and gold cyanide inhibitor complexes
|
S +31
|
S 3x +31
|
|
5fnjA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
S +31
|
S 3x +31
|
|
6equA
|
X-ray crystal structure of the human carbonic anhydrase ii adduct with a membrane-impermeant inhibitor
|
S +31
|
S 3x +31
|
|
3mwoA
|
Human carbonic anhydrase ii in a doubled monoclinic cell: a re-determination
|
S +31
|
S 3x +31
|
|
5e2sA
|
Crystal structure of human carbonic anhydrase ii in complex with the 4-(2-iso-propylphenyl)benzenesulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
1cvbA
|
Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
4pyyA
|
Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
|
S +31
|
S 3x +31
|
|
4dz7A
|
Hca ii in complex with novel sulfonamide inhibitors set d
|
S +31
|
S 3x +31
|
|
4heyA
|
Activity enhancers of h64a variant of human carbonic anhydrase ii possess multiple binding sites within and around the enzyme structure
|
S +31
|
S 3x +31
|
|
2cabA
|
Structure, refinement and function of carbonic anhydrase isozymes. refinement of human carbonic anhydrase i
|
S +31
|
S 3x +31
|
|
5ehvA
|
Human carbonic anhydrase ii in complex with ligand
|
S +31
|
S 3x +31
|
|
2vvaX
|
Human carbonic anhydrase in complex with co2
|
S +31
|
S 3x +31
|
|
1bzmA
|
Drug-protein interactions: structure of sulfonamide drug complexed with human carbonic anhydrase i
|
S +31
|
S 3x +31
|
|
4q6dA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-[(z)-azepan-1-yldiazenyl]benzenesulfonamide
|
S +31
|
S 3x +31
|
|
5amlA
|
Three dimensional structure of human carbonic anhydrase ii in complex with 2-(but-2-yn-1-ylsulfamoyl)-4-sulfamoylbenzoic acid
|
S +31
|
S 3x +31
|
|
5eh8A
|
Human carbonic anhydrase ii in complex with ligand
|
S +31
|
S 3x +31
|
|
5e2nA
|
Crystal structure of human carbonic anhydrase isozyme xiii with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
|
S +31
|
S 3x +31
|
|
3dcsA
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
S +31
|
S 3x +31
|
|
5fl6A
|
Three dimensional structure of human carbonic anhydrase ix in complex with 5-(1-(4-methylphenyl)-1h-1,2,3-triazol-4-yl)thiophene-2- sulfonamide
|
S +31
|
S 3x +31
|
|
4lhiA
|
Crystal structure of human carbonic anhydrase isozyme ii with 5-(phenylsulfonyl)thiophene-2-sulfonamide
|
S +31
|
S 3x +31
|
|
3oyqA
|
Structure of human carbonic anhydrase ii complexed with 5,6-dihydro-benzo[h]cinnolin-3-ylamine
|
S +31
|
S 3x +31
|
|
1eouA
|
Crystal structure of human carbonic anhydrase ii complexed with an anticonvulsant sugar sulfamate
|
S +31
|
S 3x +31
|
|
4zaoA
|
Genetically engineered carbonic anhydrase ix
|
S +31
|
S 3x +31
|
|
1oq5A
|
Carbonic anhydrase ii in complex with nanomolar inhibitor
|
S +31
|
S 3x +31
|
|
5fniA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
S +31
|
S 3x +31
|
|
4r5bA
|
Human carbonic anhydrase ii in complex with a carbohydrate-based sulfamate
|
S +31
|
S 3x +31
|
|
1rayA
|
The structure of human carbonic anhydrase ii in complex with bromide and azide
|
S +31
|
S 3x +31
|
|
1caiA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
3m5tA
|
Fragment tethered to carbonic anhydrase ii h64c mutant
|
S +31
|
S 3x +31
|
|
4pxxA
|
Crystal structure of a highly thermal stabilized variant of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
4e3dA
|
Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
|
S +31
|
S 3x +31
|
|
3n2pA
|
Crystal structure of human carbonic anhydrase ii in complex with a benzenesulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
3t5zA
|
Crystal structure of the human carbonic anhydrase ii in complex with n-methoxy-benzenesulfonamide
|
S +31
|
S 3x +31
|
|
1dcbA
|
Structure of an engineered metal binding site in human carbonic anhydrase ii reveals the architecture of a regulatory cysteine switch
|
S +31
|
S 3x +31
|
|
3s9tA
|
Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6bccA
|
Joint x-ray/neutron structure of human carbonic anhydrase ii in complex with ethoxzolamide
|
S +31
|
S 3x +31
|
|
5dsjA
|
Structure of co2 released holo-form of human carbonic anhydrase ii with 50 sec warming
|
S +31
|
S 3x +31
|
|
5ti0A
|
Crystal structure of 2-hydroxycyclohepta-2,4,6-triene-1-thione bound to human carbonic anhydrase 2 l198g
|
S +31
|
S 3x +31
|
|
3hkqA
|
Human carbonic anhydrase ii in complex with 1-s-d-galactopyranosylsulfonamide
|
S +31
|
S 3x +31
|
|
5jn7A
|
Carbonic anhydrase ii in complex with u-ch3
|
S +31
|
S 3x +31
|
|
4qjwA
|
Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with inhibitor
|
S +31
|
S 3x +31
|
|
1cayA
|
Wild-type and e106q mutant carbonic anhydrase complexed with acetate
|
S +31
|
S 3x +31
|
|
4qsiA
|
Crystal structure of human carbonic anhydrase isozyme ii with 5-{[(4-tert-buthyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}-2-chlorobenzenesulfonamide
|
S +31
|
S 3x +31
|
|
3sapA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-{[(5-butyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
S +31
|
S 3x +31
|
|
4qtlA
|
Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
|
S +31
|
S 3x +31
|
|
3m2zA
|
Fragment tethered to carbonic anhydrase ii h64c mutant
|
S +31
|
S 3x +31
|
|
3p5lA
|
Human carbonic anhydrase complexed with sodium 4-cyano-4-phenylpiperidine-1-carbodithioate
|
S +31
|
S 3x +31
|
|
4kniA
|
Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide
|
S +31
|
S 3x +31
|
|
5jg5B
|
Human carbonic anhydrase ii (v121t/f131y) complexed with benzo[d]thiazole-2-sulfonamide
|
S +31
|
S 3x +31
|
|
3sbhA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
|
S +31
|
S 3x +31
|
|
1calA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
5jn1A
|
Carbonic anhydrase ix-mimic in complex with u-ch3
|
S +31
|
S 3x +31
|
|
3ks3A
|
High resolution structure of human carbonic anhydrase ii at 0.9 a
|
S +31
|
S 3x +31
|
|
4cnrA
|
Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion co2 capture
|
S +31
|
S 3x +31
|
|
3mmfA
|
Crystal structure of human carbonic anhydrase ii in complex with a 1,3,5-triazine-substituted benzenesulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
3s71B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
S +31
|
S 3x +31
|
|
3dcwA
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
S +31
|
S 3x +31
|
|
4idrX
|
Human carbonic anhydrase ii proton transfer double mutant
|
S +31
|
S 3x +31
|
|
3hs4A
|
Human carbonic anhydrase ii complexed with acetazolamide
|
S +31
|
S 3x +31
|
|
6cjvA
|
Carbonic anhydrase ix-mimic in complex with sucralose
|
S +31
|
S 3x +31
|
|
4ruxA
|
Crystal structure of human carbonic anhydrase ii in complex with 4-(allyloxy)benzenesulfonamide
|
S +31
|
S 3x +31
|
|
5jgtB
|
Human carbonic anhydrase ii (f131y/l198a) complexed with 1,3-thiazole-2-sulfonamide
|
S +31
|
S 3x +31
|
|
5dsiA
|
Structure of co2 bound holo-form of human carbonic anhydrase ii with 0 sec (no) warming
|
S +31
|
S 3x +31
|
|
1rj6A
|
Crystal structure of the extracellular domain of murine carbonic anhydrase xiv in complex with acetazolamide
|
S +31
|
S 3x +31
|
|
5llcA
|
Crystal structure of human carbonic anhydrase isozyme ii with 3-(methylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide
|
S +31
|
S 3x +31
|
|
3dd0A
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
S +31
|
S 3x +31
|
|
4mo8A
|
The crystal structure of the human carbonic anhydrase ii in complex with n-[2-(2-methyl-5-nitro-1h-imidazol-1-yl)ethyl]sulfamide
|
S +31
|
S 3x +31
|
|
3s78B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
S +31
|
S 3x +31
|
|
3v3jA
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
S +31
|
S 3x +31
|
|
1g6vA
|
Complex of the camelid heavy-chain antibody fragment cab-ca05 with bovine carbonic anhydrase
|
S +31
|
S 3x +31
|
|
2it4A
|
X ray structure of the complex between carbonic anhydrase i and the phosphonate antiviral drug foscarnet
|
S +31
|
S 3x +31
|
|
5a6hA
|
Synthesis, carbonic anhydrase inhibition and protein x-ray structure of the unusual natural product primary sulfonamide psammaplin c
|
S +31
|
S 3x +31
|
|
4g0cA
|
Neutron structure of acetazolamide-bound human carbonic anhydrase ii reveal molecular details of drug binding.
|
S +31
|
S 3x +31
|
|
5u0dA
|
Identification of a new zinc binding chemotype by fragment screening
|
S +31
|
S 3x +31
|
|
1v9iC
|
Crystal structure analysis of the site specific mutant (q253c) of bovine carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
1h9nA
|
H119n carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
3dvdA
|
X-ray crystal structure of mutant n62d of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
4zx1A
|
Engineered carbonic anhydrase ix mimic in complex with a glucosyl sulfamate inhibitor
|
S +31
|
S 3x +31
|
|
3hkuA
|
Human carbonic anhydrase ii in complex with topiramate
|
S +31
|
S 3x +31
|
|
4itoA
|
Human ca ii inhibition by novel sulfonamide
|
S +31
|
S 3x +31
|
|
3v3hB
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
S +31
|
S 3x +31
|
|
5bnlA
|
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins
|
S +31
|
S 3x +31
|
|
4ilxA
|
Structure of human carbonic anhydrase ii in complex with an adamantyl sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
2povA
|
The crystal structure of the human carbonic anhydrase ii in complex with 4-amino-6-chloro-benzene-1,3-disulfonamide
|
S +31
|
S 3x +31
|
|
5n1rA
|
Crystal structure of human carbonic anhydrase ii in complex with the inhibitor 4'-pyrazol-1-ylmethyl-biphenyl-4-sulfonamide
|
S +31
|
S 3x +31
|
|
5jq0A
|
Crystal structure of human carbonic anhydrase ii in complex with benzoxaborole at ph=8.7
|
S +31
|
S 3x +31
|
|
2fmzA
|
Carbonic anhydrase activators. activation of isoforms i, ii, iv, va, vii and xiv with l- and d- phenylalanine, structure with d-phenylalanine.
|
S +31
|
S 3x +31
|
|
5cacA
|
Refined structure of human carbonic anhydrase ii at 2.0 angstroms resolution
|
S +31
|
S 3x +31
|
|
5flqA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
S +31
|
S 3x +31
|
|
1t9nA
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
5o07A
|
The crystal structure of the human carbonic anhydrase ii in complex with a nitroimidazole sulfamate inhibitor
|
S +31
|
S 3x +31
|
|
3qykA
|
Human carbonic anhydrase ii complexed with triple ring benzene sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
5n1sA
|
Crystal structure of human carbonic anhydrase ii in complex with the inhibitor 4-(1h-indol-2-yl)-benzenesulfonamide
|
S +31
|
S 3x +31
|
|
5e2rA
|
The crystal structure of the human carbonic anhydrase ii in complex with a 1,1'-biphenyl-4-sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
1cazA
|
Wild-type and e106q mutant carbonic anhydrase complexed with acetate
|
S +31
|
S 3x +31
|
|
4rh2A
|
Crystal structure of human carbonic anhydrase ii in complex with 2-(6-hydroxy-3-oxo-3h-xanthen-9-yl)-5-{3-1-(4-sulfamoyl-phenyl)-1h-[1,2,3]triazol-4-ylmethyl-thioureido}-benzoic acid
|
S +31
|
S 3x +31
|
|
1xq0A
|
Structure of human carbonic anhydrase ii with 4-[(3-bromo-4-o-sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
|
S +31
|
S 3x +31
|
|
1fqrA
|
X-ray crystal structure of cobalt-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
|
S +31
|
S 3x +31
|
|
5a25A
|
Rational engineering of a mesophilic carbonic anhydrase to an extreme halotolerant biocatalyst
|
S +31
|
S 3x +31
|
|
3ni5A
|
Carbonic anhydrase inhibitor: c1 family
|
S +31
|
S 3x +31
|
|
3k7kA
|
Crystal structure of the complex between carbonic anhydrase ii and anions
|
S +31
|
S 3x +31
|
|
1fr4A
|
X-ray crystal structure of copper-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
|
S +31
|
S 3x +31
|
|
1cahA
|
Structure of cobalt carbonic anhydrase complexed with bicarbonate
|
S +31
|
S 3x +31
|
|
5jmzA
|
Carbonic anhydrase ix-mimic in complex with u-no2
|
S +31
|
S 3x +31
|
|
3v3iB
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
S +31
|
S 3x +31
|
|
5amgA
|
Three dimensional structure of human carbonic anhydrase ii in complex with 2-(pentylsulfamoyl)-4-sulfamoylbenzoic acid
|
S +31
|
S 3x +31
|
|
1ugaA
|
Human carbonic anhydrase ii[hcaii] (e.c.4.2.1.1) mutant with ala 65 replaced by phe (a65f)
|
S +31
|
S 3x +31
|
|
4hu1A
|
Crystal structure of human carbonic anhydrase isozyme xiii with the inhibitor.
|
S +31
|
S 3x +31
|
|
5e2kA
|
Crystal structure of human carbonic anhydrase ii in complex with the 4-(3-aminophenyl)benzenesulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
1zsbA
|
Carbonic anhydrase ii mutant e117q, transition state analogue acetazolamide
|
S +31
|
S 3x +31
|
|
4n16A
|
Structure of cholate bound to human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
3t82A
|
Human carbonic anhydrase ii in complex with acetylated carbohydrate sulfamates
|
S +31
|
S 3x +31
|
|
4jszA
|
Benzenesulfonamide bound to hcaii h94c
|
S +31
|
S 3x +31
|
|
3k2fA
|
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma
|
S +31
|
S 3x +31
|
|
3kigA
|
Mutant carbonic anhydrase ii in complex with an azide and an alkyne
|
S +31
|
S 3x +31
|
|
3d9zA
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
S +31
|
S 3x +31
|
|
2q38A
|
Carbonic anhydrase ii in complex with saccharin at 1.95 angstrom
|
S +31
|
S 3x +31
|
|
2osmA
|
Inhibition of carbonic anhydrase ii by thioxolone: a mechanistic and structural study
|
S +31
|
S 3x +31
|
|
2nmxA
|
Structure of inhibitor binding to carbonic anhydrase i
|
S +31
|
S 3x +31
|
|
3rldA
|
Crystal structure of the y7i mutant of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
6g9uA
|
Three dimensional structure of human carbonic anhydrase ix in complex with sulfonamide
|