2I0TD

Crystal structure of phenylacetaldehyde derived r-carbinolamine adduct of aromatic amine dehydrogenase
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 1x +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 28-85 58 1-27, 86-94 27 9 knot
Fingerprint Knot forming loop Loop type
K +31 His59 ... Cys75 <-> Cys140 ... Cys113 <-> Cys81 ... Tqq109 <-> Trp160 ...
Chain closureLeu179 <-> His59
 probabilistic
Chain Sequence
HISLNPDLANEDEVNSCDYWRHCAVDGFLCSCCGGTTTTCPPGSTPSPIS-IGTCHNPHDGKDYLISYHDCCGKTACGRCQCNTQTRERPGYEFFLHNDVNWCMANENSTFHCTTSVLVGL
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
sequence length 121
structure length 120
publication title New insights into the reductive half-reaction mechanism of aromatic amine dehydrogenase revealed by reaction with carbinolamine substrates.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Aromatic amine dehydrogenase
missing residues 51
total genus Genus: 35
ec nomenclature ec 1.4.9.2: Aralkylamine dehydrogenase (azurin).
pdb deposition date 2006-08-11
KnotProt deposition date 2018-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF02975 Me-amine-dh_L Methylamine dehydrogenase, L chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.30.10 Mainly Beta Sandwich Electron Transport Ethylamine Dehydrogenase Electron Transport Ethylamine Dehydrogenase 2i0tD00
2.60.30.10 Mainly Beta Sandwich Electron Transport Ethylamine Dehydrogenase Electron Transport Ethylamine Dehydrogenase 2i0tD00
2AGXD 2IAAB 2OJYD 2HXCD 2IUPD 2BBKL 2AH0D 2IUQD 2Q7QD 2HJ4D 2I0TD 2HKMD 3L4OC 2MTAL 2I0SD 2HJBD 2HKRD 2J55L 2GC4B 2MADL 2OIZD 1MDAM 2IUVD 2AGYD 2GC7B 1MG2B 2IURD 2J56L 2AH1D 2H3XB 2OK4D 2AGLD 2J57K 2AGWD 1MG3B 2H47B 3C75L
chains in the KnotProt database with same CATH superfamily
2AGXD 2IAAB 2OJYD 2HXCD 2IUPD 2BBKL 2AH0D 2IUQD 2Q7QD 2HJ4D 2I0TD 2HKMD 3L4OC 2MTAL 2I0SD 2HJBD 2HKRD 2J55L 2GC4B 2MADL 2OIZD 1MDAM 2IUVD 2AGYD 2GC7B 1MG2B 2IURD 2J56L 2AH1D 2H3XB 2OK4D 2AGLD 2J57K 2AGWD 1MG3B 2H47B 3C75L
chains in the KnotProt database with same CATH topology
2AGXD 2IAAB 2OJYD 2HXCD 2IUPD 2BBKL 2AH0D 2IUQD 2Q7QD 2HJ4D 2I0TD 2HKMD 3L4OC 2MTAL 2I0SD 2HJBD 2HKRD 2J55L 2GC4B 2MADL 2OIZD 1MDAM 2IUVD 2AGYD 2GC7B 1MG2B 2IURD 2J56L 2AH1D 2H3XB 2OK4D 2AGLD 2J57K 2AGWD 1MG3B 2H47B 3C75L
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 2AGX D;  2IAA B;  2OJY D;  2HXC D;  2IUP D;  2BBK L;  2AH0 D;  2IUQ D;  2Q7Q D;  2HJ4 D;  2I0T D;  2HKM D;  3L4O C;  2MTA L;  2I0S D;  2HJB D;  2HKR D;  2J55 L;  2GC4 B;  2MAD L;  2OIZ D;  1MDA M;  2IUV D;  2AGY D;  2GC7 B;  1MG2 B;  2IUR D;  2J56 L;  2AH1 D;  2H3X B;  2OK4 D;  2AGL D;  2J57 K;  2AGW D;  1MG3 B;  2H47 B;  3C75 L; 
#chains in the KnotProt database with same CATH topology
 2AGX D;  2IAA B;  2OJY D;  2HXC D;  2IUP D;  2BBK L;  2AH0 D;  2IUQ D;  2Q7Q D;  2HJ4 D;  2I0T D;  2HKM D;  3L4O C;  2MTA L;  2I0S D;  2HJB D;  2HKR D;  2J55 L;  2GC4 B;  2MAD L;  2OIZ D;  1MDA M;  2IUV D;  2AGY D;  2GC7 B;  1MG2 B;  2IUR D;  2J56 L;  2AH1 D;  2H3X B;  2OK4 D;  2AGL D;  2J57 K;  2AGW D;  1MG3 B;  2H47 B;  3C75 L; 
#chains in the KnotProt database with same CATH homology
 2AGX D;  2IAA B;  2OJY D;  2HXC D;  2IUP D;  2BBK L;  2AH0 D;  2IUQ D;  2Q7Q D;  2HJ4 D;  2I0T D;  2HKM D;  3L4O C;  2MTA L;  2I0S D;  2HJB D;  2HKR D;  2J55 L;  2GC4 B;  2MAD L;  2OIZ D;  1MDA M;  2IUV D;  2AGY D;  2GC7 B;  1MG2 B;  2IUR D;  2J56 L;  2AH1 D;  2H3X B;  2OK4 D;  2AGL D;  2J57 K;  2AGW D;  1MG3 B;  2H47 B;  3C75 L;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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