1LNSA

Crystal structure analysis of the x-prolyl dipeptidyl aminopeptidase from lactococcus lactis
Slipknot S +31 +31 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 192-310 119 311-763 1-169 170-191 169 452 slipknot
Chain Sequence
MRFNHFSIVDKNFDEQLAELDQLGFRWSVFWDEKKILKDFLIQSPSDMTALQATAELDVIEFLKSSIELDWEIFWNIALQLLDFVPNFDFEIGKAFEYAKNSNLPQIEAEMTTENIISAFYYLLCTRRKTGMILVEHWVSEGLLPLDNHYHFFNDKSLATFDSSLLEREVLWVESPVDSEQRGENDLIKIQIIRPKSTEKLPVVMTASPYHLGINDKANDLALHDMNVELEEKTSHEIHVEQKLPQKLSAKAKELPIVDKAPYRFTHGWTYSLNDYFLTRGFASIYVAGVGTRSSDGFQTSGDYQQIYSMTAVIDWLNGRARAYTSRKKTHEIKASWANGKVAMTGKSYLGTMAYGAATTGVEGLELILAEAGISSWYNYYRENGLVRSPGGFPGEDLDVLAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLINTDKVKADVLIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSETINAYFVAKLLDRDLNLNLPPVILQENSKDQVWTMMNDFGANTQIKLPLGKTAVSFAQFDNNYDDETFKKYSKDFNVFKKDLFENKANEAVIDLELPSMLTINGPVELELRLKLNDTKGFLSAQILDFGQKKRLEDKVRVKDFKVLDRGRNFMLDDLVELPLVESPYQLVTKGFTNLQNQSLLTVSDLKADEWFTIKFELQPTIYHLEKADKLRVILYSTDFEHTVRDNRKVTYEIDLSQSKLIIPIESVKN
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 193-451 259 1-167, 736-763 168-192, 452-735 167 28 slipknot
view details
1.1 191-295 105 1-168, 317-763 169-190, 296-316 168 447 slipknot
view details
2.1 180-385 206 1-168, 397-763 169-179, 386-396 168 367 slipknot
view details
1.1 182-395 214 1-168, 407-763 169-181, 396-406 168 357 slipknot
view details
2.1 187-333 147 1-169, 349-763 170-186, 334-348 169 415 slipknot
view details
1.1 183-395 213 1-181, 407-763 182-182, 396-406 181 357 slipknot
view details
1.1 191-429 239 1-169, 450-763 170-190, 430-449 169 314 slipknot
view details
2.1 181-379 199 1-171, 391-763 172-180, 380-390 171 373 slipknot
view details
2.1 193-358 166 1-179, 376-763 180-192, 359-375 179 388 slipknot
view details
1.1 190-316 127 1-180, 327-763 181-189, 317-326 180 437 slipknot
view details
1.1 192-395 204 1-182, 406-763 183-191, 396-405 182 358 slipknot
view details
2.1 193-379 187 1-183, 395-763 184-192, 380-394 183 369 slipknot
view details
2.1 193-394 202 1-183, 396-763 184-192, 395-395 183 368 slipknot
view details
2.1 194-386 193 1-192, 397-763 193-193, 387-396 192 367 slipknot
sequence length 763
structure length 763
publication title The Structural Basis for Catalysis and Specificity of the X-prolyl dipepdidyl aminopeptidase from Lactococcus lactis
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords X-PROLYL DIPEPTIDYL AMINOPEPTIDASE
source organism Lactococcus lactis
total genus Genus: 252
ec nomenclature ec 3.4.14.11: Xaa-Pro dipeptidyl-peptidase.
pdb deposition date 2002-05-03
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02129 Peptidase_S15 X-Pro dipeptidyl-peptidase (S15 family)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-like 1lnsA04
3.40.50.1820 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Rossmann fold 1lnsA02
1LNSA 3FSGA
chains in the KnotProt database with same CATH superfamily
2VTKA 3KZCA 3M5DA 1DBIA 3VTKA 1II9A 1JS1X 1F48A 3L04A 4IVPA 1KI7A 1E2PA 1YVEI 1P75A 2FG7C 1KI4A 1KI6A 1E2HA 3FSGA 3L06A 3M4NA 1P6XA 4IVRA 1YH1A 3KZMA 2FG6C 1E2MA 4JBYA 1VTKA 3KZKA 3KZOA 1QMGA 1OF1A 1P73A 1E2NA 3L02A 2FG7X 3M4JA 3FR8A 3FR7A 1KIMA 1YRLA 2XTJA 3L05A 2G7MC 1E2KA 3RDPA 1GKUB 1OSNA 3KZNA 1KI2A 1E2JA 1E2LA 1KI8A 1P7CA 1R4NB 1KI3A 4IVQA 1LNSA 2KI5A 1P72A 1R4MB 3F0TA 1KI6B 3M5CA 1QHIA 4JBXA 1E2IA
chains in the KnotProt database with same CATH topology
3KZCA 3M5DA 1DBIA 1JS1X 3L04A 2FG7C 3FSGA 3L06A 3M4NA 1YH1A 2FG6C 3KZKA 3KZOA 3L02A 3M4JA 2FG7X 2XTJA 3L05A 2G7MC 1GKUB 3KZNA 1LNSA 3M5CA 3KZMA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1LNS A;  3FSG A; 
#chains in the KnotProt database with same CATH topology
 2VTK A;  3KZC A;  3M5D A;  1DBI A;  3VTK A;  1II9 A;  1JS1 X;  1F48 A;  3L04 A;  4IVP A;  1KI7 A;  1E2P A;  1YVE I;  1P75 A;  2FG7 C;  1KI4 A;  1KI6 A;  1E2H A;  3FSG A;  3L06 A;  3M4N A;  1P6X A;  4IVR A;  1YH1 A;  3KZM A;  2FG6 C;  1E2M A;  4JBY A;  1VTK A;  3KZK A;  3KZO A;  1QMG A;  1OF1 A;  1P73 A;  1E2N A;  3L02 A;  2FG7 X;  3M4J A;  3FR8 A;  3FR7 A;  1KIM A;  1YRL A;  2XTJ A;  3L05 A;  2G7M C;  1E2K A;  3RDP A;  1GKU B;  1OSN A;  3KZN A;  1KI2 A;  1E2J A;  1E2L A;  1KI8 A;  1P7C A;  1R4N B;  1KI3 A;  4IVQ A;  1LNS A;  2KI5 A;  1P72 A;  1R4M B;  3F0T A;  1KI6 B;  3M5C A;  1QHI A;  4JBX A;  1E2I A; 
#chains in the KnotProt database with same CATH homology
 3KZC A;  3M5D A;  1DBI A;  1JS1 X;  3L04 A;  2FG7 C;  3FSG A;  3L06 A;  3M4N A;  1YH1 A;  2FG6 C;  3KZK A;  3KZO A;  3L02 A;  3M4J A;  2FG7 X;  2XTJ A;  3L05 A;  2G7M C;  1GKU B;  3KZN A;  1LNS A;  3M5C A;  3KZM A; 
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling