1LNSA

Crystal structure analysis of the x-prolyl dipeptidyl aminopeptidase from lactococcus lactis
Slipknot S +31 +31 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 192-310 119 311-763 1-169 170-191 169 452 slipknot
Chain Sequence
MRFNHFSIVDKNFDEQLAELDQLGFRWSVFWDEKKILKDFLIQSPSDMTALQATAELDVIEFLKSSIELDWEIFWNIALQLLDFVPNFDFEIGKAFEYAKNSNLPQIEAEMTTENIISAFYYLLCTRRKTGMILVEHWVSEGLLPLDNHYHFFNDKSLATFDSSLLEREVLWVESPVDSEQRGENDLIKIQIIRPKSTEKLPVVMTASPYHLGINDKANDLALHDMNVELEEKTSHEIHVEQKLPQKLSAKAKELPIVDKAPYRFTHGWTYSLNDYFLTRGFASIYVAGVGTRSSDGFQTSGDYQQIYSMTAVIDWLNGRARAYTSRKKTHEIKASWANGKVAMTGKSYLGTMAYGAATTGVEGLELILAEAGISSWYNYYRENGLVRSPGGFPGEDLDVLAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLINTDKVKADVLIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSETINAYFVAKLLDRDLNLNLPPVILQENSKDQVWTMMNDFGANTQIKLPLGKTAVSFAQFDNNYDDETFKKYSKDFNVFKKDLFENKANEAVIDLELPSMLTINGPVELELRLKLNDTKGFLSAQILDFGQKKRLEDKVRVKDFKVLDRGRNFMLDDLVELPLVESPYQLVTKGFTNLQNQSLLTVSDLKADEWFTIKFELQPTIYHLEKADKLRVILYSTDFEHTVRDNRKVTYEIDLSQSKLIIPIESVKN
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 193-451 259 1-167, 736-763 168-192, 452-735 167 28 slipknot
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1.1 191-295 105 1-168, 317-763 169-190, 296-316 168 447 slipknot
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2.1 180-385 206 1-168, 397-763 169-179, 386-396 168 367 slipknot
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1.1 182-395 214 1-168, 407-763 169-181, 396-406 168 357 slipknot
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2.1 187-333 147 1-169, 349-763 170-186, 334-348 169 415 slipknot
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1.1 183-395 213 1-181, 407-763 182-182, 396-406 181 357 slipknot
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1.1 191-429 239 1-169, 450-763 170-190, 430-449 169 314 slipknot
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2.1 181-379 199 1-171, 391-763 172-180, 380-390 171 373 slipknot
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2.1 193-358 166 1-179, 376-763 180-192, 359-375 179 388 slipknot
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1.1 190-316 127 1-180, 327-763 181-189, 317-326 180 437 slipknot
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1.1 192-395 204 1-182, 406-763 183-191, 396-405 182 358 slipknot
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2.1 193-379 187 1-183, 395-763 184-192, 380-394 183 369 slipknot
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2.1 193-394 202 1-183, 396-763 184-192, 395-395 183 368 slipknot
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2.1 194-386 193 1-192, 397-763 193-193, 387-396 192 367 slipknot
sequence length 763
structure length 763
publication title The Structural Basis for Catalysis and Specificity of the X-prolyl dipepdidyl aminopeptidase from Lactococcus lactis
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords X-PROLYL DIPEPTIDYL AMINOPEPTIDASE
source organism Lactococcus lactis
total genus Genus: 252
ec nomenclature ec 3.4.14.11: Xaa-Pro dipeptidyl-peptidase.
pdb deposition date 2002-05-03
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02129 Peptidase_S15 X-Pro dipeptidyl-peptidase (S15 family)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-like 1lnsA04
3.40.50.1820 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Rossmann fold 1lnsA02
1LNSA 3FSGA
chains in the KnotProt database with same CATH superfamily
1E2HA 1E2LA 1R4NB 3VTKA 4IVQA 3L04A 3M5DA 1P73A 3M4NA 1KIMA 1KI3A 4IVRA 3KZKA 3RDPA 3L02A 1YH1A 2FG7X 1E2KA 1E2PA 1DBIA 2G7MC 1KI2A 1KI6A 1OSNA 3FR8A 1QHIA 2KI5A 3KZMA 2FG7C 1KI6B 1II9A 3FR7A 2XTJA 1QMGA 1E2IA 3KZOA 1JS1X 3M4JA 2FG6C 1P75A 4JBYA 3KZNA 1R4MB 1LNSA 4IVPA 1YRLA 2VTKA 1OF1A 1P72A 1KI4A 1KI8A 1KI7A 1E2MA 3KZCA 3M5CA 1P6XA 1E2NA 4JBXA 1F48A 3L05A 1YVEI 1E2JA 3F0TA 3FSGA 1VTKA 1P7CA 3L06A 1GKUB
chains in the KnotProt database with same CATH topology
3L04A 3M5DA 3M4NA 3KZKA 3L02A 1YH1A 2FG7X 1DBIA 2G7MC 3KZMA 2FG7C 2XTJA 3KZOA 1JS1X 3M4JA 2FG6C 3KZNA 1LNSA 3KZCA 3M5CA 3L05A 3FSGA 3L06A 1GKUB
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1LNS A;  3FSG A; 
#chains in the KnotProt database with same CATH topology
 1E2H A;  1E2L A;  1R4N B;  3VTK A;  4IVQ A;  3L04 A;  3M5D A;  1P73 A;  3M4N A;  1KIM A;  1KI3 A;  4IVR A;  3KZK A;  3RDP A;  3L02 A;  1YH1 A;  2FG7 X;  1E2K A;  1E2P A;  1DBI A;  2G7M C;  1KI2 A;  1KI6 A;  1OSN A;  3FR8 A;  1QHI A;  2KI5 A;  3KZM A;  2FG7 C;  1KI6 B;  1II9 A;  3FR7 A;  2XTJ A;  1QMG A;  1E2I A;  3KZO A;  1JS1 X;  3M4J A;  2FG6 C;  1P75 A;  4JBY A;  3KZN A;  1R4M B;  1LNS A;  4IVP A;  1YRL A;  2VTK A;  1OF1 A;  1P72 A;  1KI4 A;  1KI8 A;  1KI7 A;  1E2M A;  3KZC A;  3M5C A;  1P6X A;  1E2N A;  4JBX A;  1F48 A;  3L05 A;  1YVE I;  1E2J A;  3F0T A;  3FSG A;  1VTK A;  1P7C A;  3L06 A;  1GKU B; 
#chains in the KnotProt database with same CATH homology
 3L04 A;  3M5D A;  3M4N A;  3KZK A;  3L02 A;  1YH1 A;  2FG7 X;  1DBI A;  2G7M C;  3KZM A;  2FG7 C;  2XTJ A;  3KZO A;  1JS1 X;  3M4J A;  2FG6 C;  3KZN A;  1LNS A;  3KZC A;  3M5C A;  3L05 A;  3FSG A;  3L06 A;  1GKU B; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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