1YRLA

Escherichia coli ketol-acid reductoisomerase
Knot K 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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41 222-420 199 1-221, 421-487 221 67 knot
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+31 251-363 113 1-231, 418-487 232-250, 364-417 231 70 slipknot
Chain Sequence
NYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAV
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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4.1 216-426 211 1-215, 427-487 215 61 knot
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3.2 211-414 204 1-210 430-487 415-429 210 58 slipknot
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4.1 163-429 267 1-162 440-487 430-439 162 48 slipknot
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4.1 217-426 210 427-487 1-215 216-216 215 60 slipknot
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3.2 227-444 218 1-216, 472-487 217-226, 445-471 216 16 slipknot
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3.2 227-471 245 1-216, 474-487 217-226, 472-473 216 14 slipknot
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2.1 237-367 131 1-220, 390-487 221-236, 368-389 220 98 slipknot
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2.3 238-413 176 1-225, 427-487 226-237, 414-426 225 61 slipknot
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1.1 253-397 145 1-233, 413-487 234-252, 398-412 233 75 slipknot
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3.1 247-370 124 1-235, 396-487 236-246, 371-395 235 92 slipknot
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2.1 248-413 166 1-237, 427-487 238-247, 414-426 237 61 slipknot
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2.1 257-366 110 1-246, 387-487 247-256, 367-386 246 101 slipknot
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1.1 257-414 158 1-247, 429-487 248-256, 415-428 247 59 slipknot
sequence length 487
structure length 487
publication title The crystal structure of a bacterial class II ketol-acid reductoisomerase: domain conservation and evolution
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Ketol-acid reductoisomerase
source organism Escherichia coli
total genus Genus: 195
ec nomenclature ec 1.1.1.86: Ketol-acid reductoisomerase.
pdb deposition date 2005-02-04
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01450 IlvC Acetohydroxy acid isomeroreductase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1040.10 Mainly Alpha Orthogonal Bundle N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 1yrlA02
3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like Domain 1yrlA01
1QMGA 3FR8A 3ULKA 3FR7A 1R4MB 1R4NB 1YVEI 1YRLA
chains in the KnotProt database with same CATH superfamily
4IVRA 1OF1A 3KZNA 1QMGA 1YH1A 1KI7A 3ULKA 3KZOA 3FR7A 2FG7C 2KI5A 2FG7X 3KZMA 1YRLA 1E2LA 1E2KA 3F0TA 3M5DA 4JBYA 4IVQA 1E2MA 1KIMA 1KI6B 1II9A 1VTKA 1GKUB 1P72A 3M4NA 4JBXA 1R4NB 1KI3A 3M5CA 1JS1X 1P7CA 3L02A 1KI8A 1LNSA 3L05A 1E2JA 1E2NA 1KI6A 3M4JA 1OSNA 1R4MB 2XTJA 3L04A 1KI4A 1QHIA 1P6XA 1YVEI 1P73A 2VTKA 1KI2A 3FSGA 1E2HA 3KZCA 4IVPA 1E2IA 3VTKA 3FR8A 2G7MC 2FG6C 1DBIA 1E2PA 1P75A 1F48A 3L06A 3KZKA 3RDPA
chains in the KnotProt database with same CATH topology
1QMGA 3FR8A 3ULKA 3FR7A 1R4MB 1R4NB 1YVEI 1YRLA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1QMG A;  3FR8 A;  3ULK A;  3FR7 A;  1R4M B;  1R4N B;  1YVE I;  1YRL A; 
#chains in the KnotProt database with same CATH topology
 4IVR A;  1OF1 A;  3KZN A;  1QMG A;  1YH1 A;  1KI7 A;  3ULK A;  3KZO A;  3FR7 A;  2FG7 C;  2KI5 A;  2FG7 X;  3KZM A;  1YRL A;  1E2L A;  1E2K A;  3F0T A;  3M5D A;  4JBY A;  4IVQ A;  1E2M A;  1KIM A;  1KI6 B;  1II9 A;  1VTK A;  1GKU B;  1P72 A;  3M4N A;  4JBX A;  1R4N B;  1KI3 A;  3M5C A;  1JS1 X;  1P7C A;  3L02 A;  1KI8 A;  1LNS A;  3L05 A;  1E2J A;  1E2N A;  1KI6 A;  3M4J A;  1OSN A;  1R4M B;  2XTJ A;  3L04 A;  1KI4 A;  1QHI A;  1P6X A;  1YVE I;  1P73 A;  2VTK A;  1KI2 A;  3FSG A;  1E2H A;  3KZC A;  4IVP A;  1E2I A;  3VTK A;  3FR8 A;  2G7M C;  2FG6 C;  1DBI A;  1E2P A;  1P75 A;  1F48 A;  3L06 A;  3KZK A;  3RDP A; 
#chains in the KnotProt database with same CATH homology
 1QMG A;  3FR8 A;  3ULK A;  3FR7 A;  1R4M B;  1R4N B;  1YVE I;  1YRL A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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