1R4NB

Appbp1-uba3-nedd8, an e1-ubiquitin-like protein complex with atp
Cysteine knot
Loop Piercing
view details
202-c-343-b-346-c-346 199-b-343
Chain Sequence
DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATN----RTLYLQSVTSIEERTRKELGL-------VDGQEAVADVTTPQTVL-FKLHFT
sequence length 430
structure length 418
publication title The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
pubmed doi rcsb
molecule tags Cell cycle
molecule keywords amyloid beta precursor protein-binding protein 1
source organism Homo sapiens
missing residues 374-377, 395-401, 412
ec nomenclature
pdb deposition date 2003-10-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.10.520 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 1r4nB02
3.10.20.260 Alpha Beta Roll Ubiquitin-like (UB roll) Ubiquitin activating enzymes (Uba3). Chain: B, domain 3 1r4nB03
3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like Domain 1r4nB01
1YVEI 1YRLA 1QMGA 1R4MB 1R4NB 3FR8A 3FR7A
chains in the KnotProt database with same CATH superfamily
1KI6B 3FR8A 3KZNA 3M4NA 1YRLA 1F48A 2FG6C 3M4JA 1R4MB 2KI5A 1E2PA 1LNSA 1P73A 1VTKA 4IVPA 3KZMA 1DBIA 3L04A 1E2HA 1OSNA 1JS1X 3VTKA 4JBYA 1E2IA 4IVRA 3F0TA 1P72A 1E2LA 4JBXA 3L02A 1P75A 3L05A 4IVQA 1KI6A 2G7MC 3KZOA 1OF1A 3FSGA 1KI8A 1KI3A 1R4NB 1E2MA 1YH1A 3M5CA 1E2KA 3FR7A 1KI7A 1YVEI 1KI2A 3KZKA 1P7CA 1QMGA 1E2JA 1P6XA 2XTJA 3M5DA 1E2NA 2VTKA 3L06A 3KZCA 3RDPA 1GKUB 1QHIA 1II9A 1KI4A 1KIMA
chains in the KnotProt database with same CATH topology
1YVEI 1YRLA 1QMGA 1R4MB 1R4NB 3FR8A 3FR7A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1YVE I;  1YRL A;  1QMG A;  1R4M B;  1R4N B;  3FR8 A;  3FR7 A; 
#chains in the KnotProt database with same CATH topology
 1KI6 B;  3FR8 A;  3KZN A;  3M4N A;  1YRL A;  1F48 A;  2FG6 C;  3M4J A;  1R4M B;  2KI5 A;  1E2P A;  1LNS A;  1P73 A;  1VTK A;  4IVP A;  3KZM A;  1DBI A;  3L04 A;  1E2H A;  1OSN A;  1JS1 X;  3VTK A;  4JBY A;  1E2I A;  4IVR A;  3F0T A;  1P72 A;  1E2L A;  4JBX A;  3L02 A;  1P75 A;  3L05 A;  4IVQ A;  1KI6 A;  2G7M C;  3KZO A;  1OF1 A;  3FSG A;  1KI8 A;  1KI3 A;  1R4N B;  1E2M A;  1YH1 A;  3M5C A;  1E2K A;  3FR7 A;  1KI7 A;  1YVE I;  1KI2 A;  3KZK A;  1P7C A;  1QMG A;  1E2J A;  1P6X A;  2XTJ A;  3M5D A;  1E2N A;  2VTK A;  3L06 A;  3KZC A;  3RDP A;  1GKU B;  1QHI A;  1II9 A;  1KI4 A;  1KIM A; 
#chains in the KnotProt database with same CATH homology
 1YVE I;  1YRL A;  1QMG A;  1R4M B;  1R4N B;  3FR8 A;  3FR7 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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