1R4MB

Appbp1-uba3-nedd8, an e1-ubiquitin-like protein complex
Cysteine knot
Loop Piercing
view details
202-c-343-b-346-c-346 199-b-343
Chain Sequence
DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATN----RTLYLQSVTSIEERTRKELGL-------VDGQEAVADVTTPQTVL-FKLHFT
sequence length 430
structure length 418
publication title The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
pubmed doi rcsb
molecule tags Cell cycle
molecule keywords amyloid beta precursor protein-binding protein 1
source organism Homo sapiens
missing residues 374-377, 395-401, 412
ec nomenclature
pdb deposition date 2003-10-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.10.520 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 1r4mB02
3.10.20.260 Alpha Beta Roll Ubiquitin-like (UB roll) Ubiquitin activating enzymes (Uba3). Chain: B, domain 3 1r4mB03
3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like Domain 1r4mB01
1R4NB 1YVEI 1YRLA 1R4MB 3FR7A 1QMGA 3FR8A
chains in the KnotProt database with same CATH superfamily
1P75A 3KZOA 1F48A 2VTKA 1KI3A 1II9A 3KZCA 3L04A 3M4NA 1OF1A 1KI2A 1KI6A 3M5DA 2XTJA 1KIMA 1E2LA 1E2JA 4IVRA 3FR8A 1E2NA 1P72A 1P7CA 3L02A 1KI6B 1GKUB 1YH1A 2FG6C 3RDPA 1JS1X 3KZKA 1R4MB 1KI4A 3FR7A 4JBXA 1E2HA 1OSNA 1P73A 3FSGA 1VTKA 3M5CA 3M4JA 1KI7A 1P6XA 3KZMA 1YVEI 3VTKA 1DBIA 1E2PA 3L06A 1QMGA 1E2IA 4IVPA 1QHIA 1R4NB 2G7MC 1E2MA 3KZNA 1YRLA 3F0TA 4JBYA 2KI5A 1E2KA 4IVQA 1LNSA 1KI8A 3L05A
chains in the KnotProt database with same CATH topology
1R4NB 1YVEI 1YRLA 1R4MB 3FR7A 1QMGA 3FR8A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1R4N B;  1YVE I;  1YRL A;  1R4M B;  3FR7 A;  1QMG A;  3FR8 A; 
#chains in the KnotProt database with same CATH topology
 1P75 A;  3KZO A;  1F48 A;  2VTK A;  1KI3 A;  1II9 A;  3KZC A;  3L04 A;  3M4N A;  1OF1 A;  1KI2 A;  1KI6 A;  3M5D A;  2XTJ A;  1KIM A;  1E2L A;  1E2J A;  4IVR A;  3FR8 A;  1E2N A;  1P72 A;  1P7C A;  3L02 A;  1KI6 B;  1GKU B;  1YH1 A;  2FG6 C;  3RDP A;  1JS1 X;  3KZK A;  1R4M B;  1KI4 A;  3FR7 A;  4JBX A;  1E2H A;  1OSN A;  1P73 A;  3FSG A;  1VTK A;  3M5C A;  3M4J A;  1KI7 A;  1P6X A;  3KZM A;  1YVE I;  3VTK A;  1DBI A;  1E2P A;  3L06 A;  1QMG A;  1E2I A;  4IVP A;  1QHI A;  1R4N B;  2G7M C;  1E2M A;  3KZN A;  1YRL A;  3F0T A;  4JBY A;  2KI5 A;  1E2K A;  4IVQ A;  1LNS A;  1KI8 A;  3L05 A; 
#chains in the KnotProt database with same CATH homology
 1R4N B;  1YVE I;  1YRL A;  1R4M B;  3FR7 A;  1QMG A;  3FR8 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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