1R4MB

Appbp1-uba3-nedd8, an e1-ubiquitin-like protein complex
Cysteine knot
Loop Piercing
view details
202-c-343-b-346-c-346 199-b-343
Chain Sequence
DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATN----RTLYLQSVTSIEERTRKELGL-------VDGQEAVADVTTPQTVL-FKLHFT
sequence length 430
structure length 418
publication title The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
pubmed doi rcsb
molecule tags Cell cycle
molecule keywords amyloid beta precursor protein-binding protein 1
source organism Homo sapiens
missing residues 374-377, 395-401, 412
ec nomenclature
pdb deposition date 2003-10-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.10.520 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 1r4mB02
3.10.20.260 Alpha Beta Roll Ubiquitin-like (UB roll) Ubiquitin activating enzymes (Uba3). Chain: B, domain 3 1r4mB03
3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like Domain 1r4mB01
1YRLA 1R4MB 1YVEI 1R4NB 3FR7A 3FR8A 1QMGA
chains in the KnotProt database with same CATH superfamily
1II9A 1P6XA 1KI2A 1YH1A 1E2IA 1E2NA 1KI3A 1JS1X 1KI6A 1KIMA 1R4NB 1GKUB 1E2JA 3L06A 1YVEI 2XTJA 1E2HA 2FG6C 1OF1A 3KZMA 1DBIA 4IVRA 3L02A 3RDPA 1OSNA 1E2PA 2G7MC 3L05A 1KI4A 3M4NA 1KI7A 2VTKA 1KI6B 1VTKA 3KZKA 1P75A 1E2KA 3VTKA 1YRLA 3F0TA 4IVPA 1KI8A 1QHIA 3FR7A 1P73A 4IVQA 3FR8A 1E2MA 3KZOA 1QMGA 4JBYA 3M5DA 1P7CA 3KZNA 3M4JA 1R4MB 3KZCA 1P72A 3L04A 1LNSA 3M5CA 1E2LA 2KI5A 4JBXA 1F48A 3FSGA
chains in the KnotProt database with same CATH topology
1YRLA 1R4MB 1YVEI 1R4NB 3FR7A 3FR8A 1QMGA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1YRL A;  1R4M B;  1YVE I;  1R4N B;  3FR7 A;  3FR8 A;  1QMG A; 
#chains in the KnotProt database with same CATH topology
 1II9 A;  1P6X A;  1KI2 A;  1YH1 A;  1E2I A;  1E2N A;  1KI3 A;  1JS1 X;  1KI6 A;  1KIM A;  1R4N B;  1GKU B;  1E2J A;  3L06 A;  1YVE I;  2XTJ A;  1E2H A;  2FG6 C;  1OF1 A;  3KZM A;  1DBI A;  4IVR A;  3L02 A;  3RDP A;  1OSN A;  1E2P A;  2G7M C;  3L05 A;  1KI4 A;  3M4N A;  1KI7 A;  2VTK A;  1KI6 B;  1VTK A;  3KZK A;  1P75 A;  1E2K A;  3VTK A;  1YRL A;  3F0T A;  4IVP A;  1KI8 A;  1QHI A;  3FR7 A;  1P73 A;  4IVQ A;  3FR8 A;  1E2M A;  3KZO A;  1QMG A;  4JBY A;  3M5D A;  1P7C A;  3KZN A;  3M4J A;  1R4M B;  3KZC A;  1P72 A;  3L04 A;  1LNS A;  3M5C A;  1E2L A;  2KI5 A;  4JBX A;  1F48 A;  3FSG A; 
#chains in the KnotProt database with same CATH homology
 1YRL A;  1R4M B;  1YVE I;  1R4N B;  3FR7 A;  3FR8 A;  1QMG A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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