1R4M | KnotProt

Cysteine knot

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				Loop	Piercing
view details				202-c-343-b-346-c-346	199-b-343

Chain Sequence

DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATN----RTLYLQSVTSIEERTRKELGL-------VDGQEAVADVTTPQTVL-FKLHFT

missing residues	374-377, 395-401, 412
publication title	The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. pubmed doi rcsb
structure length	418
molecule tags	Cell cycle
source organism	Homo sapiens
sequence length	430
molecule keywords	amyloid beta precursor protein-binding protein 1
ec nomenclature
pdb deposition date	2003-10-07

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.10.520	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Ubiquitin activating enzymes (Uba3). Chain: B, domain 2	1r4mB02
3.10.20.260	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Ubiquitin activating enzymes (Uba3). Chain: B, domain 3	1r4mB03
3.40.50.720	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	NAD(P)-binding Rossmann-like Domain	1r4mB01

3FR7A 1YRLA 1R4NB 3FR8A 1QMGA 1YVEI 1R4MB
chains in the KnotProt database with same CATH superfamily

3RDPA 3M4NA 3FSGA 3L04A 1E2NA 1KI6A 4IVPA 3KZKA 1QMGA 3KZCA 1DBIA 3L02A 2FG7C 1VTKA 1GKUB 4JBXA 3FR8A 1II9A 2FG6C 2G7MC 4IVQA 3F0TA 1LNSA 1E2HA 1KI4A 1JS1X 3KZMA 2XTJA 3M5DA 3FR7A 1QHIA 1YRLA 1OF1A 3M5CA 3L05A 4IVRA 1E2IA 1KI3A 1P75A 2VTKA 1YH1A 1F48A 1YVEI 1E2LA 1KI8A 3M4JA 1R4MB 1E2PA 4JBYA 2FG7X 1E2JA 1KI2A 1P72A 1R4NB 3KZOA 1P7CA 2KI5A 3L06A 1E2MA 1KI7A 1E2KA 1KIMA 1P6XA 3VTKA 1OSNA 1KI6B 1P73A 3KZNA
chains in the KnotProt database with same CATH topology

3FR7A 1YRLA 1R4NB 3FR8A 1QMGA 1YVEI 1R4MB
chains in the KnotProt database with same CATH homology

#chains in the KnotProt database with same CATH superfamily
 3FR7 A;  1YRL A;  1R4N B;  3FR8 A;  1QMG A;  1YVE I;  1R4M B; 
#chains in the KnotProt database with same CATH topology
 3RDP A;  3M4N A;  3FSG A;  3L04 A;  1E2N A;  1KI6 A;  4IVP A;  3KZK A;  1QMG A;  3KZC A;  1DBI A;  3L02 A;  2FG7 C;  1VTK A;  1GKU B;  4JBX A;  3FR8 A;  1II9 A;  2FG6 C;  2G7M C;  4IVQ A;  3F0T A;  1LNS A;  1E2H A;  1KI4 A;  1JS1 X;  3KZM A;  2XTJ A;  3M5D A;  3FR7 A;  1QHI A;  1YRL A;  1OF1 A;  3M5C A;  3L05 A;  4IVR A;  1E2I A;  1KI3 A;  1P75 A;  2VTK A;  1YH1 A;  1F48 A;  1YVE I;  1E2L A;  1KI8 A;  3M4J A;  1R4M B;  1E2P A;  4JBY A;  2FG7 X;  1E2J A;  1KI2 A;  1P72 A;  1R4N B;  3KZO A;  1P7C A;  2KI5 A;  3L06 A;  1E2M A;  1KI7 A;  1E2K A;  1KIM A;  1P6X A;  3VTK A;  1OSN A;  1KI6 B;  1P73 A;  3KZN A; 
#chains in the KnotProt database with same CATH homology
 3FR7 A;  1YRL A;  1R4N B;  3FR8 A;  1QMG A;  1YVE I;  1R4M B;

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similar chains in the KnotProt database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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