| Loop | Piercing | ||||
|---|---|---|---|---|---|
| view details | 202-c-343-b-346-c-346 | 199-b-343 |
Chain Sequence |
DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATN----RTLYLQSVTSIEERTRKELGL-------VDGQEAVADVTTPQTVL-FKLHFT
|
| sequence length |
430
|
| structure length |
418
|
| publication title |
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
pubmed doi rcsb |
| molecule tags |
Cell cycle
|
| molecule keywords |
amyloid beta precursor protein-binding protein 1
|
| source organism |
Homo sapiens
|
| missing residues |
374-377, 395-401, 412
|
| ec nomenclature | |
| pdb deposition date | 2003-10-07 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 | ||
| Alpha Beta | Roll | Ubiquitin-like (UB roll) | Ubiquitin activating enzymes (Uba3). Chain: B, domain 3 | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain |
#chains in the KnotProt database with same CATH superfamily 1QMG A; 1R4M B; 1R4N B; 3FR7 A; 1YVE I; 3FR8 A; 1YRL A; #chains in the KnotProt database with same CATH topology 1R4M B; 1KIM A; 1R4N B; 1JS1 X; 2VTK A; 1OSN A; 2XTJ A; 1KI8 A; 1E2M A; 1OF1 A; 2FG6 C; 3F0T A; 1LNS A; 3M5D A; 1F48 A; 1E2I A; 3M4J A; 3VTK A; 1QMG A; 1KI7 A; 1E2P A; 1P6X A; 1E2K A; 1QHI A; 1KI2 A; 1P7C A; 3L06 A; 3KZC A; 1KI4 A; 4IVR A; 3M4N A; 1II9 A; 3KZK A; 1GKU B; 1P75 A; 1E2N A; 1YRL A; 3M5C A; 1KI3 A; 1E2J A; 1P73 A; 1VTK A; 3FR7 A; 1YH1 A; 3FR8 A; 3L04 A; 4JBX A; 1DBI A; 2KI5 A; 3KZM A; 1P72 A; 3KZO A; 3L02 A; 1E2L A; 4IVQ A; 1KI6 B; 3FSG A; 4IVP A; 3RDP A; 1YVE I; 2G7M C; 4JBY A; 1E2H A; 1KI6 A; 3KZN A; 3L05 A; #chains in the KnotProt database with same CATH homology 1QMG A; 1R4M B; 1R4N B; 3FR7 A; 1YVE I; 3FR8 A; 1YRL A;
#similar chains in the KnotProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
