1R4N | KnotProt

Cysteine knot

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Help Cysteine knot data interpretation Full screen

				Loop	Piercing
view details				202-c-343-b-346-c-346	199-b-343

Chain Sequence

DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATN----RTLYLQSVTSIEERTRKELGL-------VDGQEAVADVTTPQTVL-FKLHFT

sequence length	430
structure length	418
publication title	The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. pubmed doi rcsb
molecule tags	Cell cycle
molecule keywords	amyloid beta precursor protein-binding protein 1
source organism	Homo sapiens
missing residues	374-377, 395-401, 412
ec nomenclature
pdb deposition date	2003-10-07

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.10.520	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Ubiquitin activating enzymes (Uba3). Chain: B, domain 2	1r4nB02
3.10.20.260	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Ubiquitin activating enzymes (Uba3). Chain: B, domain 3	1r4nB03
3.40.50.720	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	NAD(P)-binding Rossmann-like Domain	1r4nB01

1QMGA 1YRLA 1R4NB 3FR8A 3FR7A 1R4MB 1YVEI
chains in the KnotProt database with same CATH superfamily

3RDPA 3L04A 1E2HA 1VTKA 1YRLA 3L02A 3M5CA 1KI8A 2XTJA 1E2JA 2G7MC 1P7CA 1KIMA 1YVEI 3F0TA 1E2PA 1KI6A 4IVRA 1KI3A 1P72A 3KZNA 3M5DA 1E2NA 1P73A 1R4MB 1JS1X 3FR7A 3KZMA 1E2IA 1GKUB 3KZOA 4JBXA 1KI6B 1E2LA 1E2MA 1KI7A 2VTKA 1P75A 3L06A 2KI5A 1YH1A 3FR8A 3M4NA 4JBYA 4IVQA 1E2KA 1OF1A 3M4JA 1II9A 1KI4A 1KI2A 1P6XA 1R4NB 1QMGA 4IVPA 3L05A 1QHIA 2FG6C 3KZCA 3KZKA 1OSNA 1DBIA 1LNSA 3FSGA 3VTKA 1F48A
chains in the KnotProt database with same CATH topology

1QMGA 1YRLA 1R4NB 3FR8A 3FR7A 1R4MB 1YVEI
chains in the KnotProt database with same CATH homology

#chains in the KnotProt database with same CATH superfamily
 1QMG A;  1YRL A;  1R4N B;  3FR8 A;  3FR7 A;  1R4M B;  1YVE I; 
#chains in the KnotProt database with same CATH topology
 3RDP A;  3L04 A;  1E2H A;  1VTK A;  1YRL A;  3L02 A;  3M5C A;  1KI8 A;  2XTJ A;  1E2J A;  2G7M C;  1P7C A;  1KIM A;  1YVE I;  3F0T A;  1E2P A;  1KI6 A;  4IVR A;  1KI3 A;  1P72 A;  3KZN A;  3M5D A;  1E2N A;  1P73 A;  1R4M B;  1JS1 X;  3FR7 A;  3KZM A;  1E2I A;  1GKU B;  3KZO A;  4JBX A;  1KI6 B;  1E2L A;  1E2M A;  1KI7 A;  2VTK A;  1P75 A;  3L06 A;  2KI5 A;  1YH1 A;  3FR8 A;  3M4N A;  4JBY A;  4IVQ A;  1E2K A;  1OF1 A;  3M4J A;  1II9 A;  1KI4 A;  1KI2 A;  1P6X A;  1R4N B;  1QMG A;  4IVP A;  3L05 A;  1QHI A;  2FG6 C;  3KZC A;  3KZK A;  1OSN A;  1DBI A;  1LNS A;  3FSG A;  3VTK A;  1F48 A; 
#chains in the KnotProt database with same CATH homology
 1QMG A;  1YRL A;  1R4N B;  3FR8 A;  3FR7 A;  1R4M B;  1YVE I;

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similar chains in the KnotProt database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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