3L05A

Crystal structure of n-acetyl-l-ornithine transcarbamylase e92s mutant complexed with carbamyl phosphate and n-succinyl-l-norvaline
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 174-251 78 1-173, 252-332 173 81 knot
Chain Sequence
LKHFLNTQDWSRAELDALLTQAALFKRNKLGSELKGKSIALVFFNPSMRTRTSFELGAFQLGGHAVVLQPGKDAWPIEFNLGTVMDGDTSEHIAEVARVLGRYVDLIGVRAFPKFVDWSKDREDQVLKSFAKYSPVPVINMETITHPCQELAHALALQEHFGTPDLRGKKYVLTWTYHPKPLNTAVANSALTIATRMGMDVTLLCPTPDYILDERYMDWAAQNVAESGGSLQVSHDIDSAYAGADVVYAKSWGALPFFGNWEPEKPIRDQYQHFIVDERKMALTNNGVFSHCLPLRRNVKATDAVMDSPNCIAIDEAENRLHVQKAIMAALV
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 174-251 78 1-173, 252-332 173 81 knot
view details
2.1 158-248 91 1-157 254-332 249-253 157 79 slipknot
view details
2.1 175-325 151 1-173, 332-332 174-174, 326-331 173 1 slipknot
view details
3.1 175-297 123 1-173, 301-332 174-174, 298-300 173 32 slipknot
sequence length 332
structure length 332
publication title A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase.
pubmed doi rcsb
molecule tags Transferase
molecule keywords N-acetylornithine carbamoyltransferase
source organism Xanthomonas campestris pv. campestris
total genus Genus: 125
ec nomenclature ec 2.1.3.9: N-acetylornithine carbamoyltransferase.
pdb deposition date 2009-12-09
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00185 OTCace Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.50.1370 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Rossmann fold 3l05A01
3.40.50.1370 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Rossmann fold 3l05A02
3M4JA 3L05A 3M5CA 1JS1X 3L06A 3KZCA 1YH1A 2G7MC 3L04A 2FG6C 3M4NA 3KZMA 3KZKA 3KZOA 3M5DA 3KZNA 3L02A
chains in the KnotProt database with same CATH superfamily
1R4MB 1KIMA 1JS1X 1R4NB 2VTKA 1OSNA 2XTJA 1KI8A 1E2MA 1OF1A 2FG6C 3F0TA 1LNSA 3M5DA 1F48A 1E2IA 3M4JA 3VTKA 1QMGA 1KI7A 1E2PA 1P6XA 1E2KA 1QHIA 1KI2A 1P7CA 3L06A 3KZCA 1KI4A 4IVRA 3M4NA 1II9A 3KZKA 1GKUB 1P75A 1E2NA 1YRLA 3M5CA 1KI3A 1E2JA 1P73A 1VTKA 3FR7A 1YH1A 3FR8A 3L04A 4JBXA 1DBIA 2KI5A 3KZMA 1P72A 3KZOA 3L02A 1E2LA 4IVQA 1KI6B 3FSGA 4IVPA 3RDPA 1YVEI 2G7MC 4JBYA 1E2HA 1KI6A 3KZNA 3L05A
chains in the KnotProt database with same CATH topology
1JS1X 2XTJA 2FG6C 1LNSA 3M5DA 3M4JA 3L06A 3KZCA 3M4NA 3KZKA 1GKUB 3M5CA 1YH1A 3L04A 1DBIA 3KZMA 3KZOA 3L02A 3FSGA 2G7MC 3KZNA 3L05A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3M4J A;  3L05 A;  3M5C A;  1JS1 X;  3L06 A;  3KZC A;  1YH1 A;  2G7M C;  3L04 A;  2FG6 C;  3M4N A;  3KZM A;  3KZK A;  3KZO A;  3M5D A;  3KZN A;  3L02 A; 
#chains in the KnotProt database with same CATH topology
 1R4M B;  1KIM A;  1JS1 X;  1R4N B;  2VTK A;  1OSN A;  2XTJ A;  1KI8 A;  1E2M A;  1OF1 A;  2FG6 C;  3F0T A;  1LNS A;  3M5D A;  1F48 A;  1E2I A;  3M4J A;  3VTK A;  1QMG A;  1KI7 A;  1E2P A;  1P6X A;  1E2K A;  1QHI A;  1KI2 A;  1P7C A;  3L06 A;  3KZC A;  1KI4 A;  4IVR A;  3M4N A;  1II9 A;  3KZK A;  1GKU B;  1P75 A;  1E2N A;  1YRL A;  3M5C A;  1KI3 A;  1E2J A;  1P73 A;  1VTK A;  3FR7 A;  1YH1 A;  3FR8 A;  3L04 A;  4JBX A;  1DBI A;  2KI5 A;  3KZM A;  1P72 A;  3KZO A;  3L02 A;  1E2L A;  4IVQ A;  1KI6 B;  3FSG A;  4IVP A;  3RDP A;  1YVE I;  2G7M C;  4JBY A;  1E2H A;  1KI6 A;  3KZN A;  3L05 A; 
#chains in the KnotProt database with same CATH homology
 1JS1 X;  2XTJ A;  2FG6 C;  1LNS A;  3M5D A;  3M4J A;  3L06 A;  3KZC A;  3M4N A;  3KZK A;  1GKU B;  3M5C A;  1YH1 A;  3L04 A;  1DBI A;  3KZM A;  3KZO A;  3L02 A;  3FSG A;  2G7M C;  3KZN A;  3L05 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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