3FR8A

Rice ketolacid reductoisomerase in complex with mg2+-nadph
Slipknot S 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 273-388 116 1-248, 444-501 249-272, 389-443 248 58 slipknot
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41 239-442 204 1-238, 443-501 238 58 slipknot
Chain Sequence
AAMPSLDFDTSVFNKEKVSLAGHEEYIVRGGRNLFPLLPEAFKGIKQIGVIGWGSQGPAQAQNLRDSLAEAKSDIVVKIGLRKGSKSFDEARAAGFTEESGTLGDIWETVSGSDLVLLLISDAAQADNYEKIFSHMKPNSILGLSHGFLLGHLQSAGLDFPKNISVIAVCPKGMGPSVRRLYVQGKEINGAGINSSFAVHQDVDGRATDVALGWSVALGSPFTFATTLEQEYKSDIFGERGILLGAVHGIVEALFRRYTEQGMDEEMAYKNTVEGITGIISKTISKKGMLEVYNSLTEEGKKEFNKAYSASFYPCMDILYECYEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGNIDQTRMWKVGEKVRSTRPENDLGPLHPFTAGVYVALMMAQIEVLRKKGHSYSEIINESVIESVDSLNPFMHARGVAFMVDNCSTTARLGSRKWAPRFDYILTQQAFVTVDKDAPINQDLISNFMSDPVHGAIEVCAELRPTVDISV
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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4.1 237-452 216 1-236, 453-501 236 49 knot
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3.2 236-439 204 1-235 458-501 440-457 235 44 slipknot
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3.2 245-461 217 1-236, 487-501 237-244, 462-486 236 15 slipknot
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3.2 245-486 242 1-236, 490-501 237-244, 487-489 236 12 slipknot
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3.2 246-462 217 1-244, 487-501 245-245, 463-486 244 15 slipknot
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3.2 246-486 241 1-244, 490-501 245-245, 487-489 244 12 slipknot
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2.3 247-438 192 1-234, 452-501 235-246, 439-451 234 50 slipknot
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2.1 259-391 133 1-237, 417-501 238-258, 392-416 237 85 slipknot
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1.1 277-394 118 1-243, 440-501 244-276, 395-439 243 62 slipknot
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2.1 277-439 163 1-246, 441-501 247-276, 440-440 246 61 slipknot
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3.1 269-392 124 1-258, 395-501 259-268, 393-394 258 107 slipknot
sequence length 501
structure length 501
publication title Conformational changes in a plant ketol-acid reductoisomerase upon Mg(2+) and NADPH binding as revealed by two crystal structures
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Putative ketol-acid reductoisomerase (Os05g0573700 protein)
source organism Oryza sativa japonica group
total genus Genus: 183
ec nomenclature ec 1.1.1.86: Ketol-acid reductoisomerase.
ec 1.1.1.86: Ketol-acid reductoisomerase (NADP(+)).
pdb deposition date 2009-01-08
KnotProt deposition date 2018-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01450 IlvC Acetohydroxy acid isomeroreductase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1040.10 Mainly Alpha Orthogonal Bundle N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 3fr8A02
3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like Domain 3fr8A01
1R4MB 1YRLA 1YVEI 3ULKA 1QMGA 1R4NB 3FR7A 3FR8A
chains in the KnotProt database with same CATH superfamily
1OF1A 3F0TA 3L02A 1KI8A 1YRLA 3L06A 1P73A 3KZNA 3ULKA 1R4NB 1E2PA 1VTKA 4JBYA 1E2KA 1LNSA 1E2NA 1OSNA 4IVQA 3KZKA 1KI3A 4JBXA 2VTKA 3M5CA 3FSGA 2G7MC 3VTKA 2FG6C 4IVPA 3FR8A 3KZOA 1P7CA 1E2MA 3RDPA 1KIMA 3M5DA 1GKUB 1E2LA 1JS1X 3M4NA 2KI5A 3L05A 2FG7X 3KZMA 1KI6B 3KZCA 1KI6A 1II9A 3L04A 2XTJA 2FG7C 1E2IA 1E2HA 1KI2A 3M4JA 1P6XA 1R4MB 1E2JA 1YVEI 1KI4A 1QHIA 1QMGA 3FR7A 1F48A 1DBIA 1P75A 1KI7A 4IVRA 1P72A 1YH1A
chains in the KnotProt database with same CATH topology
1R4MB 1YRLA 1YVEI 3ULKA 1QMGA 1R4NB 3FR7A 3FR8A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1R4M B;  1YRL A;  1YVE I;  3ULK A;  1QMG A;  1R4N B;  3FR7 A;  3FR8 A; 
#chains in the KnotProt database with same CATH topology
 1OF1 A;  3F0T A;  3L02 A;  1KI8 A;  1YRL A;  3L06 A;  1P73 A;  3KZN A;  3ULK A;  1R4N B;  1E2P A;  1VTK A;  4JBY A;  1E2K A;  1LNS A;  1E2N A;  1OSN A;  4IVQ A;  3KZK A;  1KI3 A;  4JBX A;  2VTK A;  3M5C A;  3FSG A;  2G7M C;  3VTK A;  2FG6 C;  4IVP A;  3FR8 A;  3KZO A;  1P7C A;  1E2M A;  3RDP A;  1KIM A;  3M5D A;  1GKU B;  1E2L A;  1JS1 X;  3M4N A;  2KI5 A;  3L05 A;  2FG7 X;  3KZM A;  1KI6 B;  3KZC A;  1KI6 A;  1II9 A;  3L04 A;  2XTJ A;  2FG7 C;  1E2I A;  1E2H A;  1KI2 A;  3M4J A;  1P6X A;  1R4M B;  1E2J A;  1YVE I;  1KI4 A;  1QHI A;  1QMG A;  3FR7 A;  1F48 A;  1DBI A;  1P75 A;  1KI7 A;  4IVR A;  1P72 A;  1YH1 A; 
#chains in the KnotProt database with same CATH homology
 1R4M B;  1YRL A;  1YVE I;  3ULK A;  1QMG A;  1R4N B;  3FR7 A;  3FR8 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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