3RDP | KnotProt

Genus: 110

Slipknot S +3₁

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Help Knotting data interpretation Full screen

					Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details				+3₁	5-117	113	1-4	305-329	118-304	4	25	slipknot

Chain Sequence

MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSG---------------PRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE

Whole chain analysis

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Subchain analysis

Knotoid cutoff: 0.5

Knotoid matrix content: 1

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Help Knotoid subchains data interpretation Full screen

		Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details	3.1	4-154	151	1-3	177-314	155-176	3	138	slipknot
view details	2.1	8-156	149	1-7	289-314	157-288	7	26	slipknot
view details	2.1	8-120	113		1-2, 155-314	3-7, 121-154	2	160	slipknot
view details	2.1	9-172	164		1-7, 283-314	8-8, 173-282	7	32	slipknot

sequence length	329
structure length	314
publication title	Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo. pubmed doi rcsb
molecule tags	Transferase
molecule keywords	Thymidine kinase
source organism	Human herpesvirus 1
missing residues	220-234
total genus	Genus: 110
ec nomenclature	ec 2.7.1.21: Thymidine kinase.
pdb deposition date	2011-04-01
KnotProt deposition date	2014-08-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00693	Herpes_TK	Thymidine kinase from herpesvirus

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	3rdpA00

3RDPA 1E2HA 1VTKA 1KI8A 1E2JA 1P7CA 1KIMA 3F0TA 1E2PA 1KI6A 4IVRA 1KI3A 1P72A 1E2NA 1P73A 1E2IA 1GKUB 4JBXA 1KI6B 1E2LA 1E2MA 1KI7A 2VTKA 1P75A 2KI5A 4JBYA 4IVQA 1E2KA 1OF1A 1II9A 1KI4A 1KI2A 1P6XA 4IVPA 1QHIA 1OSNA 3VTKA 1F48A
chains in the KnotProt database with same CATH superfamily

3RDPA 3L04A 1E2HA 1VTKA 1YRLA 3L02A 3M5CA 1KI8A 2XTJA 1E2JA 2G7MC 1P7CA 1KIMA 1YVEI 3F0TA 1E2PA 1KI6A 4IVRA 1KI3A 1P72A 3KZNA 3M5DA 1E2NA 1P73A 1R4MB 1JS1X 3FR7A 3KZMA 1E2IA 1GKUB 3KZOA 4JBXA 1KI6B 1E2LA 1E2MA 1KI7A 2VTKA 1P75A 3L06A 2KI5A 1YH1A 3FR8A 3M4NA 4JBYA 4IVQA 1E2KA 1OF1A 3M4JA 1II9A 1KI4A 1KI2A 1P6XA 1R4NB 1QMGA 4IVPA 3L05A 1QHIA 2FG6C 3KZCA 3KZKA 1OSNA 1DBIA 1LNSA 3FSGA 3VTKA 1F48A
chains in the KnotProt database with same CATH topology

#chains in the KnotProt database with same CATH superfamily
 3RDP A;  1E2H A;  1VTK A;  1KI8 A;  1E2J A;  1P7C A;  1KIM A;  3F0T A;  1E2P A;  1KI6 A;  4IVR A;  1KI3 A;  1P72 A;  1E2N A;  1P73 A;  1E2I A;  1GKU B;  4JBX A;  1KI6 B;  1E2L A;  1E2M A;  1KI7 A;  2VTK A;  1P75 A;  2KI5 A;  4JBY A;  4IVQ A;  1E2K A;  1OF1 A;  1II9 A;  1KI4 A;  1KI2 A;  1P6X A;  4IVP A;  1QHI A;  1OSN A;  3VTK A;  1F48 A; 
#chains in the KnotProt database with same CATH topology
 3RDP A;  3L04 A;  1E2H A;  1VTK A;  1YRL A;  3L02 A;  3M5C A;  1KI8 A;  2XTJ A;  1E2J A;  2G7M C;  1P7C A;  1KIM A;  1YVE I;  3F0T A;  1E2P A;  1KI6 A;  4IVR A;  1KI3 A;  1P72 A;  3KZN A;  3M5D A;  1E2N A;  1P73 A;  1R4M B;  1JS1 X;  3FR7 A;  3KZM A;  1E2I A;  1GKU B;  3KZO A;  4JBX A;  1KI6 B;  1E2L A;  1E2M A;  1KI7 A;  2VTK A;  1P75 A;  3L06 A;  2KI5 A;  1YH1 A;  3FR8 A;  3M4N A;  4JBY A;  4IVQ A;  1E2K A;  1OF1 A;  3M4J A;  1II9 A;  1KI4 A;  1KI2 A;  1P6X A;  1R4N B;  1QMG A;  4IVP A;  3L05 A;  1QHI A;  2FG6 C;  3KZC A;  3KZK A;  1OSN A;  1DBI A;  1LNS A;  3FSG A;  3VTK A;  1F48 A; 
#chains in the KnotProt database with same CATH homology
 3RDP A;  1E2H A;  1VTK A;  1KI8 A;  1E2J A;  1P7C A;  1KIM A;  3F0T A;  1E2P A;  1KI6 A;  4IVR A;  1KI3 A;  1P72 A;  1E2N A;  1P73 A;  1E2I A;  1GKU B;  4JBX A;  1KI6 B;  1E2L A;  1E2M A;  1KI7 A;  2VTK A;  1P75 A;  2KI5 A;  4JBY A;  4IVQ A;  1E2K A;  1OF1 A;  1II9 A;  1KI4 A;  1KI2 A;  1P6X A;  4IVP A;  1QHI A;  1OSN A;  3VTK A;  1F48 A;

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similar chains in the KnotProt database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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3RDPA

Slipknot S +31

Chain Sequence

pfam database annotations

Slipknot S +3₁