1CNCA

Compensatory plastic effects in the redesign of protein-zinc binding sites
Genus: 76
Alphaknot: P00918
Slipknot S +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 22-253 232 254-256 1-3 4-21 3 2 slipknot
Chain Sequence
WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFCFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASF
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 3x +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 21-253 233 254-256 1-2 3-20 2 2 slipknot
Fingerprint Knot forming loop Loop type
K +31 Trp5 ... Cys94 <->
Bridging ionZn262
<-> His96 ...
Chain closurePhe260 <-> Trp5
 probabilistic
K +31 Trp5 ... His96 <->
Bridging ionZn262
<-> His119 ...
Chain closurePhe260 <-> Trp5
 probabilistic
K +31 Trp5 ... Cys94 <->
Bridging ionZn262
<-> His119 ...
Chain closurePhe260 <-> Trp5
 probabilistic
Chain Sequence
WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFCFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASF
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 23-250 228 1-22, 251-255 22 5 knot
sequence length 255
structure length 255
publication title Structural consequences of redesigning a protein-zinc binding site.
pubmed doi rcsb
molecule tags Lyase(oxo-acid)
molecule keywords CARBONIC ANHYDRASE II
source organism Homo sapiens
total genus Genus: 76
ec nomenclature ec 4.2.1.1: Carbonate dehydratase.
pdb deposition date 1994-06-13
KnotProt deposition date 2018-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00194 Carb_anhydrase Eukaryotic-type carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 1cncA00
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 1cncA00
3MNIA 4CA2A 3DVDA 3DC9A 3KWAA 1Y7WA 3NI5A 3C7PA 1I9OA 2HFWA 1DMYA 1F2WA 1CNCA 1TH9A 1YDAA 3D0NA 2FOSA 1FQRA 1CNIA 3MHCA 1FR7A 2HFXA 3M96A 1CINA 3N3JA 3CAJA 4CACA 2POUA 1CRAA 3M2YA 2VVAX 1FQLA 1I9LA 3ML5A 3F7BA 2OSMA 1YDBA 2WEOA 1BNNA 3DC3A 2FOQA 1CANA 3JXGA 1ZE8A 1CVFA 3MMFA 2FNKA 2O4ZA 1OKNA 1FLJA 3JXHC 2HFYA 1CA2A 3BL1A 2WEGA 1CAYA 1RJ5A 3MNKA 2Q38A 2X7UA 3M5SA 1CNJA 2HNCA 3OIMA 3D92A 2NXTA 3M1WA 3K7KA 3M5TA 2POVA 2NNOA 3DVCA 3F7UA 1HCBA 1CCTA 2AW1A 2HD6A 1CVCA 3KKXA 3IGPA 1I90A 3ZNCA 1G0EA 1CNGA 3M98A 2AX2A 2FNNA 1CAHA 1BZMA 1FSQA 1RJ6A 1TE3X 1KWQA 2FOUA 2CBBA 3N2PA 1MUAA 1BV3A 3ML2A 7CA2A 2WEHA 3D8WA 1LG5A 2FW4A 1CVEA 1EOUA 3MHOA 3DA2A 1URTA 1BN3A 3DCCA 3OKUA 1CALA 3MNHA 3DVBA 1H9QA 3HLJA 1T9NA 1HEDA 3KOKA 2CBEA 3N0NA 1IF7A 1I91A 1AZMA 1HVAA 1UGFA 1CVAA 1G48A 2Q1QA 2X7TA 1YO2A 1TBTX 3F4XA 1I9MA 1LZVA 3EFTA 2GD8A 1KOPA 2NNGA 2EU2A 3IBUA 3DCWA 3M2ZA 3M5EA 3DAZA 3CA2A 1BN1A 1HCAA 2FNMA 1Z93A 2EU3A 1LG6A 1CAIA 3K34A 1KWRA 1IF4A 1THKA 3FFPX 1LGDA 1I9PA 3OILA 3MNAA 1YDCA 3CZVA 2WEJA 3GZ0A 1CNYA 3DV7A 6CA2A 1TG9A 1AVNA 1G0FA 2IT4A 3JXFA 1BNTA 1BNWA 3P4VA 4PYYA 2VVBX 3KIGA 3FE4A 3IBLA 3OIKA 3F8EA 3IEOA 1RZBA 1XEVA 1FSNA 1BCDA 1J9WA 2NWOA 3M3XA 1CVBA 1DCAA 5CA2A 3B4FA 1CNXA 3D9ZA 1CAZA 3MZCA 3DD8A 2NXSA 1XPZA 2W2JA 3HKTA 3FW3A 3N4BA 1IF5A 2NMXA 3HFPA 1XQ0A 2CBDA 2NNVA 3MHMA 1UGDA 2WD2A 1CA3A 3M67A 1RAYA 3DBUA 2NWYA 3MYQA 1ZSCA 1G52A 1RZEA 1DCBA 2GEHA 2NWZA 1CNHA 3IBIA 1H9NA 1TTMA 1G3ZA 1CVDA 3LXEA 1CAOA 1HEAA 3HS4A 1CCSA 2ZNCA 1JV0A 1G53A 1CIMA 3BL0A 1FSRA 1IF9A 1G4JA 1KEQA 12CAA 1KOQA 2CBAA 1Z97A 3M1JA 3KONA 1HUHA 1UGBA 2HL4A 1YO0A 3BETA 3M40A 1RZDA 9CA2A 2Q1BA 3R17B 1BNQA 1IF6A 3B1BA 2X7SA 1AM6A 1FR4A 3PO6A 1CAJA 1RZAA 1BICA 1CVHA 2HOCA 3HKNA 3MDZA 2H15A 2CA2A 2ILIA 2EZ7A 1A42A 1CILA 3M2NA 1UGEA 1BNUA 1G46A 1ZNCA 1UGAA 2NWPA 3DD0A 1CNWA 1V9EA 1G45A 1RAZA 3EFIA 3M1QA 3PYKA 2FMZA 2HKKA 1FQNA 2F14A 1FQMA 1CAKA 3IQKA 5CACA 1CRMA 3K2FA 1CCUA 3MNUA 3R16A 1XEGA 1IF8A 1CAMA 1BNMA 1I9NA 1OQ5A 3OKVA 1V9IC 1JD0A 2WD3A 1BN4A 1HEBA 2NNSA 1RZCA 3HKQA 2NN7A 1OKMA 2POWA 1G4OA 3MHIA 3HKUA 2NN1A 3IAIA 3DCSA 3MHLA 2CABA 1ZSBA 1HUGA 3IBNA 1HECA 2CBCA 1TEUX 1I9QA 3D93A 1YDDA 1TG3A 3MNJA 1G6VA 2ABEA 3NJ9A 2OSFA 3MWOA 1CZMA 3L14A 1YO1A 1G1DA 2FMGA 1I8ZA 1H4NA 3KS3A 8CA2A 1LUGA 2NXRA 1ZSAA 1BNVA
chains in the KnotProt database with same CATH superfamily
3MNIA 4CA2A 3DVDA 3DC9A 3KWAA 1Y7WA 3NI5A 3C7PA 1I9OA 2HFWA 1DMYA 1F2WA 1CNCA 1TH9A 1YDAA 3D0NA 2FOSA 1FQRA 1CNIA 3MHCA 1FR7A 2HFXA 3M96A 1CINA 3N3JA 3CAJA 4CACA 2POUA 1CRAA 3M2YA 2VVAX 1FQLA 1I9LA 3ML5A 3F7BA 2OSMA 1YDBA 2WEOA 1BNNA 3DC3A 2FOQA 1CANA 3JXGA 1ZE8A 1CVFA 3MMFA 2FNKA 2O4ZA 1OKNA 1FLJA 3JXHC 2HFYA 1CA2A 3BL1A 2WEGA 1CAYA 1RJ5A 3MNKA 2Q38A 2X7UA 3M5SA 1CNJA 2HNCA 3OIMA 3D92A 2NXTA 3M1WA 3K7KA 3M5TA 2POVA 2NNOA 3DVCA 3F7UA 1HCBA 1CCTA 2AW1A 2HD6A 1CVCA 3KKXA 3IGPA 1I90A 3ZNCA 1G0EA 1CNGA 3M98A 2AX2A 2FNNA 1CAHA 1BZMA 1FSQA 1RJ6A 1TE3X 1KWQA 2FOUA 2CBBA 3N2PA 1MUAA 1BV3A 3ML2A 7CA2A 2WEHA 3D8WA 1LG5A 2FW4A 1CVEA 1EOUA 3MHOA 3DA2A 1URTA 1BN3A 3DCCA 3OKUA 1CALA 3MNHA 3DVBA 1H9QA 3HLJA 1T9NA 1HEDA 3KOKA 2CBEA 3N0NA 1IF7A 1I91A 1AZMA 1HVAA 1UGFA 1CVAA 1G48A 2Q1QA 2X7TA 1YO2A 1TBTX 3F4XA 1I9MA 1LZVA 3EFTA 2GD8A 1KOPA 2NNGA 2EU2A 3IBUA 3DCWA 3M2ZA 3M5EA 3DAZA 3CA2A 1BN1A 1HCAA 2FNMA 1Z93A 2EU3A 1LG6A 1CAIA 3K34A 1KWRA 1IF4A 1THKA 3FFPX 1LGDA 1I9PA 3OILA 3MNAA 1YDCA 3CZVA 2WEJA 3GZ0A 1CNYA 3DV7A 6CA2A 1TG9A 1AVNA 1G0FA 2IT4A 3JXFA 1BNTA 1BNWA 3P4VA 4PYYA 2VVBX 3KIGA 3FE4A 3IBLA 3OIKA 3F8EA 3IEOA 1RZBA 1XEVA 1FSNA 1BCDA 1J9WA 2NWOA 3M3XA 1CVBA 1DCAA 5CA2A 3B4FA 1CNXA 3D9ZA 1CAZA 3MZCA 3DD8A 2NXSA 1XPZA 2W2JA 3HKTA 3FW3A 3N4BA 1IF5A 2NMXA 3HFPA 1XQ0A 2CBDA 2NNVA 3MHMA 1UGDA 2WD2A 1CA3A 3M67A 1RAYA 3DBUA 2NWYA 3MYQA 1ZSCA 1G52A 1RZEA 1DCBA 2GEHA 2NWZA 1CNHA 3IBIA 1H9NA 1TTMA 1G3ZA 1CVDA 3LXEA 1CAOA 1HEAA 3HS4A 1CCSA 2ZNCA 1JV0A 1G53A 1CIMA 3BL0A 1FSRA 1IF9A 1G4JA 1KEQA 12CAA 1KOQA 2CBAA 1Z97A 3M1JA 3KONA 1HUHA 1UGBA 2HL4A 1YO0A 3BETA 3M40A 1RZDA 9CA2A 2Q1BA 3R17B 1BNQA 1IF6A 3B1BA 2X7SA 1AM6A 1FR4A 3PO6A 1CAJA 1RZAA 1BICA 1CVHA 2HOCA 3HKNA 3MDZA 2H15A 2CA2A 2ILIA 2EZ7A 1A42A 1CILA 3M2NA 1UGEA 1BNUA 1G46A 1ZNCA 1UGAA 2NWPA 3DD0A 1CNWA 1V9EA 1G45A 1RAZA 3EFIA 3M1QA 3PYKA 2FMZA 2HKKA 1FQNA 2F14A 1FQMA 1CAKA 3IQKA 5CACA 1CRMA 3K2FA 1CCUA 3MNUA 3R16A 1XEGA 1IF8A 1CAMA 1BNMA 1I9NA 1OQ5A 3OKVA 1V9IC 1JD0A 2WD3A 1BN4A 1HEBA 2NNSA 1RZCA 3HKQA 2NN7A 1OKMA 2POWA 1G4OA 3MHIA 3HKUA 2NN1A 3IAIA 3DCSA 3MHLA 2CABA 1ZSBA 1HUGA 3IBNA 1HECA 2CBCA 1TEUX 1I9QA 3D93A 1YDDA 1TG3A 3MNJA 1G6VA 2ABEA 3NJ9A 2OSFA 3MWOA 1CZMA 3L14A 1YO1A 1G1DA 2FMGA 1I8ZA 1H4NA 3KS3A 8CA2A 1LUGA 2NXRA 1ZSAA 1BNVA
chains in the KnotProt database with same CATH topology
3MNIA 4CA2A 3DVDA 3DC9A 3KWAA 1Y7WA 3NI5A 3C7PA 1I9OA 2HFWA 1DMYA 1F2WA 1CNCA 1TH9A 1YDAA 3D0NA 2FOSA 1FQRA 1CNIA 3MHCA 1FR7A 2HFXA 3M96A 1CINA 3N3JA 3CAJA 4CACA 2POUA 1CRAA 3M2YA 2VVAX 1FQLA 1I9LA 3ML5A 3F7BA 2OSMA 1YDBA 2WEOA 1BNNA 3DC3A 2FOQA 1CANA 3JXGA 1ZE8A 1CVFA 3MMFA 2FNKA 2O4ZA 1OKNA 1FLJA 3JXHC 2HFYA 1CA2A 3BL1A 2WEGA 1CAYA 1RJ5A 3MNKA 2Q38A 2X7UA 3M5SA 1CNJA 2HNCA 3OIMA 3D92A 2NXTA 3M1WA 3K7KA 3M5TA 2POVA 2NNOA 3DVCA 3F7UA 1HCBA 1CCTA 2AW1A 2HD6A 1CVCA 3KKXA 3IGPA 1I90A 3ZNCA 1G0EA 1CNGA 3M98A 2AX2A 2FNNA 1CAHA 1BZMA 1FSQA 1RJ6A 1TE3X 1KWQA 2FOUA 2CBBA 3N2PA 1MUAA 1BV3A 3ML2A 7CA2A 2WEHA 3D8WA 1LG5A 2FW4A 1CVEA 1EOUA 3MHOA 3DA2A 1URTA 1BN3A 3DCCA 3OKUA 1CALA 3MNHA 3DVBA 1H9QA 3HLJA 1T9NA 1HEDA 3KOKA 2CBEA 3N0NA 1IF7A 1I91A 1AZMA 1HVAA 1UGFA 1CVAA 1G48A 2Q1QA 2X7TA 1YO2A 1TBTX 3F4XA 1I9MA 1LZVA 3EFTA 2GD8A 1KOPA 2NNGA 2EU2A 3IBUA 3DCWA 3M2ZA 3M5EA 3DAZA 3CA2A 1BN1A 1HCAA 2FNMA 1Z93A 2EU3A 1LG6A 1CAIA 3K34A 1KWRA 1IF4A 1THKA 3FFPX 1LGDA 1I9PA 3OILA 3MNAA 1YDCA 3CZVA 2WEJA 3GZ0A 1CNYA 3DV7A 6CA2A 1TG9A 1AVNA 1G0FA 2IT4A 3JXFA 1BNTA 1BNWA 3P4VA 2VVBX 3KIGA 3FE4A 3IBLA 3OIKA 3F8EA 3IEOA 1RZBA 1XEVA 1FSNA 1BCDA 1J9WA 2NWOA 3M3XA 1CVBA 1DCAA 5CA2A 3B4FA 1CNXA 3D9ZA 1CAZA 3MZCA 3DD8A 2NXSA 1XPZA 2W2JA 3HKTA 3FW3A 3N4BA 1IF5A 2NMXA 3HFPA 1XQ0A 2CBDA 2NNVA 3MHMA 1UGDA 2WD2A 1CA3A 3M67A 1RAYA 3DBUA 2NWYA 3MYQA 1ZSCA 1G52A 1RZEA 1DCBA 2GEHA 2NWZA 1CNHA 3IBIA 1H9NA 1TTMA 1G3ZA 1CVDA 3LXEA 1CAOA 1HEAA 3HS4A 1CCSA 2ZNCA 1JV0A 1G53A 1CIMA 3BL0A 1FSRA 1IF9A 1G4JA 1KEQA 12CAA 1KOQA 2CBAA 1Z97A 3M1JA 3KONA 1HUHA 1UGBA 2HL4A 1YO0A 3BETA 3M40A 1RZDA 9CA2A 2Q1BA 3R17B 1BNQA 1IF6A 3B1BA 2X7SA 1AM6A 1FR4A 3PO6A 1CAJA 1RZAA 1BICA 1CVHA 2HOCA 3HKNA 3MDZA 2H15A 2CA2A 2ILIA 2EZ7A 1A42A 1CILA 3M2NA 1UGEA 1BNUA 1G46A 1ZNCA 1UGAA 2NWPA 3DD0A 1CNWA 1V9EA 1G45A 1RAZA 3EFIA 3M1QA 3PYKA 2FMZA 2HKKA 1FQNA 2F14A 1FQMA 1CAKA 3IQKA 5CACA 1CRMA 3K2FA 1CCUA 3MNUA 3R16A 1XEGA 1IF8A 1CAMA 1BNMA 1I9NA 1OQ5A 3OKVA 1V9IC 1JD0A 2WD3A 1BN4A 1HEBA 2NNSA 1RZCA 3HKQA 2NN7A 1OKMA 2POWA 1G4OA 3MHIA 3HKUA 2NN1A 3IAIA 3DCSA 3MHLA 2CABA 1ZSBA 1HUGA 3IBNA 1HECA 2CBCA 1TEUX 1I9QA 3D93A 1YDDA 1TG3A 3MNJA 1G6VA 2ABEA 3NJ9A 2OSFA 3MWOA 1CZMA 3L14A 1YO1A 1G1DA 2FMGA 1I8ZA 1H4NA 3KS3A 8CA2A 1LUGA 2NXRA 1ZSAA 1BNVA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 3MNI A;  4CA2 A;  3DVD A;  3DC9 A;  3KWA A;  1Y7W A;  3NI5 A;  3C7P A;  1I9O A;  2HFW A;  1DMY A;  1F2W A;  1CNC A;  1TH9 A;  1YDA A;  3D0N A;  2FOS A;  1FQR A;  1CNI A;  3MHC A;  1FR7 A;  2HFX A;  3M96 A;  1CIN A;  3N3J A;  3CAJ A;  4CAC A;  2POU A;  1CRA A;  3M2Y A;  2VVA X;  1FQL A;  1I9L A;  3ML5 A;  3F7B A;  2OSM A;  1YDB A;  2WEO A;  1BNN A;  3DC3 A;  2FOQ A;  1CAN A;  3JXG A;  1ZE8 A;  1CVF A;  3MMF A;  2FNK A;  2O4Z A;  1OKN A;  1FLJ A;  3JXH C;  2HFY A;  1CA2 A;  3BL1 A;  2WEG A;  1CAY A;  1RJ5 A;  3MNK A;  2Q38 A;  2X7U A;  3M5S A;  1CNJ A;  2HNC A;  3OIM A;  3D92 A;  2NXT A;  3M1W A;  3K7K A;  3M5T A;  2POV A;  2NNO A;  3DVC A;  3F7U A;  1HCB A;  1CCT A;  2AW1 A;  2HD6 A;  1CVC A;  3KKX A;  3IGP A;  1I90 A;  3ZNC A;  1G0E A;  1CNG A;  3M98 A;  2AX2 A;  2FNN A;  1CAH A;  1BZM A;  1FSQ A;  1RJ6 A;  1TE3 X;  1KWQ A;  2FOU A;  2CBB A;  3N2P A;  1MUA A;  1BV3 A;  3ML2 A;  7CA2 A;  2WEH A;  3D8W A;  1LG5 A;  2FW4 A;  1CVE A;  1EOU A;  3MHO A;  3DA2 A;  1URT A;  1BN3 A;  3DCC A;  3OKU A;  1CAL A;  3MNH A;  3DVB A;  1H9Q A;  3HLJ A;  1T9N A;  1HED A;  3KOK A;  2CBE A;  3N0N A;  1IF7 A;  1I91 A;  1AZM A;  1HVA A;  1UGF A;  1CVA A;  1G48 A;  2Q1Q A;  2X7T A;  1YO2 A;  1TBT X;  3F4X A;  1I9M A;  1LZV A;  3EFT A;  2GD8 A;  1KOP A;  2NNG A;  2EU2 A;  3IBU A;  3DCW A;  3M2Z A;  3M5E A;  3DAZ A;  3CA2 A;  1BN1 A;  1HCA A;  2FNM A;  1Z93 A;  2EU3 A;  1LG6 A;  1CAI A;  3K34 A;  1KWR A;  1IF4 A;  1THK A;  3FFP X;  1LGD A;  1I9P A;  3OIL A;  3MNA A;  1YDC A;  3CZV A;  2WEJ A;  3GZ0 A;  1CNY A;  3DV7 A;  6CA2 A;  1TG9 A;  1AVN A;  1G0F A;  2IT4 A;  3JXF A;  1BNT A;  1BNW A;  3P4V A;  4PYY A;  2VVB X;  3KIG A;  3FE4 A;  3IBL A;  3OIK A;  3F8E A;  3IEO A;  1RZB A;  1XEV A;  1FSN A;  1BCD A;  1J9W A;  2NWO A;  3M3X A;  1CVB A;  1DCA A;  5CA2 A;  3B4F A;  1CNX A;  3D9Z A;  1CAZ A;  3MZC A;  3DD8 A;  2NXS A;  1XPZ A;  2W2J A;  3HKT A;  3FW3 A;  3N4B A;  1IF5 A;  2NMX A;  3HFP A;  1XQ0 A;  2CBD A;  2NNV A;  3MHM A;  1UGD A;  2WD2 A;  1CA3 A;  3M67 A;  1RAY A;  3DBU A;  2NWY A;  3MYQ A;  1ZSC A;  1G52 A;  1RZE A;  1DCB A;  2GEH A;  2NWZ A;  1CNH A;  3IBI A;  1H9N A;  1TTM A;  1G3Z A;  1CVD A;  3LXE A;  1CAO A;  1HEA A;  3HS4 A;  1CCS A;  2ZNC A;  1JV0 A;  1G53 A;  1CIM A;  3BL0 A;  1FSR A;  1IF9 A;  1G4J A;  1KEQ A;  12CA A;  1KOQ A;  2CBA A;  1Z97 A;  3M1J A;  3KON A;  1HUH A;  1UGB A;  2HL4 A;  1YO0 A;  3BET A;  3M40 A;  1RZD A;  9CA2 A;  2Q1B A;  3R17 B;  1BNQ A;  1IF6 A;  3B1B A;  2X7S A;  1AM6 A;  1FR4 A;  3PO6 A;  1CAJ A;  1RZA A;  1BIC A;  1CVH A;  2HOC A;  3HKN A;  3MDZ A;  2H15 A;  2CA2 A;  2ILI A;  2EZ7 A;  1A42 A;  1CIL A;  3M2N A;  1UGE A;  1BNU A;  1G46 A;  1ZNC A;  1UGA A;  2NWP A;  3DD0 A;  1CNW A;  1V9E A;  1G45 A;  1RAZ A;  3EFI A;  3M1Q A;  3PYK A;  2FMZ A;  2HKK A;  1FQN A;  2F14 A;  1FQM A;  1CAK A;  3IQK A;  5CAC A;  1CRM A;  3K2F A;  1CCU A;  3MNU A;  3R16 A;  1XEG A;  1IF8 A;  1CAM A;  1BNM A;  1I9N A;  1OQ5 A;  3OKV A;  1V9I C;  1JD0 A;  2WD3 A;  1BN4 A;  1HEB A;  2NNS A;  1RZC A;  3HKQ A;  2NN7 A;  1OKM A;  2POW A;  1G4O A;  3MHI A;  3HKU A;  2NN1 A;  3IAI A;  3DCS A;  3MHL A;  2CAB A;  1ZSB A;  1HUG A;  3IBN A;  1HEC A;  2CBC A;  1TEU X;  1I9Q A;  3D93 A;  1YDD A;  1TG3 A;  3MNJ A;  1G6V A;  2ABE A;  3NJ9 A;  2OSF A;  3MWO A;  1CZM A;  3L14 A;  1YO1 A;  1G1D A;  2FMG A;  1I8Z A;  1H4N A;  3KS3 A;  8CA2 A;  1LUG A;  2NXR A;  1ZSA A;  1BNV A; 
#chains in the KnotProt database with same CATH topology
 3MNI A;  4CA2 A;  3DVD A;  3DC9 A;  3KWA A;  1Y7W A;  3NI5 A;  3C7P A;  1I9O A;  2HFW A;  1DMY A;  1F2W A;  1CNC A;  1TH9 A;  1YDA A;  3D0N A;  2FOS A;  1FQR A;  1CNI A;  3MHC A;  1FR7 A;  2HFX A;  3M96 A;  1CIN A;  3N3J A;  3CAJ A;  4CAC A;  2POU A;  1CRA A;  3M2Y A;  2VVA X;  1FQL A;  1I9L A;  3ML5 A;  3F7B A;  2OSM A;  1YDB A;  2WEO A;  1BNN A;  3DC3 A;  2FOQ A;  1CAN A;  3JXG A;  1ZE8 A;  1CVF A;  3MMF A;  2FNK A;  2O4Z A;  1OKN A;  1FLJ A;  3JXH C;  2HFY A;  1CA2 A;  3BL1 A;  2WEG A;  1CAY A;  1RJ5 A;  3MNK A;  2Q38 A;  2X7U A;  3M5S A;  1CNJ A;  2HNC A;  3OIM A;  3D92 A;  2NXT A;  3M1W A;  3K7K A;  3M5T A;  2POV A;  2NNO A;  3DVC A;  3F7U A;  1HCB A;  1CCT A;  2AW1 A;  2HD6 A;  1CVC A;  3KKX A;  3IGP A;  1I90 A;  3ZNC A;  1G0E A;  1CNG A;  3M98 A;  2AX2 A;  2FNN A;  1CAH A;  1BZM A;  1FSQ A;  1RJ6 A;  1TE3 X;  1KWQ A;  2FOU A;  2CBB A;  3N2P A;  1MUA A;  1BV3 A;  3ML2 A;  7CA2 A;  2WEH A;  3D8W A;  1LG5 A;  2FW4 A;  1CVE A;  1EOU A;  3MHO A;  3DA2 A;  1URT A;  1BN3 A;  3DCC A;  3OKU A;  1CAL A;  3MNH A;  3DVB A;  1H9Q A;  3HLJ A;  1T9N A;  1HED A;  3KOK A;  2CBE A;  3N0N A;  1IF7 A;  1I91 A;  1AZM A;  1HVA A;  1UGF A;  1CVA A;  1G48 A;  2Q1Q A;  2X7T A;  1YO2 A;  1TBT X;  3F4X A;  1I9M A;  1LZV A;  3EFT A;  2GD8 A;  1KOP A;  2NNG A;  2EU2 A;  3IBU A;  3DCW A;  3M2Z A;  3M5E A;  3DAZ A;  3CA2 A;  1BN1 A;  1HCA A;  2FNM A;  1Z93 A;  2EU3 A;  1LG6 A;  1CAI A;  3K34 A;  1KWR A;  1IF4 A;  1THK A;  3FFP X;  1LGD A;  1I9P A;  3OIL A;  3MNA A;  1YDC A;  3CZV A;  2WEJ A;  3GZ0 A;  1CNY A;  3DV7 A;  6CA2 A;  1TG9 A;  1AVN A;  1G0F A;  2IT4 A;  3JXF A;  1BNT A;  1BNW A;  3P4V A;  4PYY A;  2VVB X;  3KIG A;  3FE4 A;  3IBL A;  3OIK A;  3F8E A;  3IEO A;  1RZB A;  1XEV A;  1FSN A;  1BCD A;  1J9W A;  2NWO A;  3M3X A;  1CVB A;  1DCA A;  5CA2 A;  3B4F A;  1CNX A;  3D9Z A;  1CAZ A;  3MZC A;  3DD8 A;  2NXS A;  1XPZ A;  2W2J A;  3HKT A;  3FW3 A;  3N4B A;  1IF5 A;  2NMX A;  3HFP A;  1XQ0 A;  2CBD A;  2NNV A;  3MHM A;  1UGD A;  2WD2 A;  1CA3 A;  3M67 A;  1RAY A;  3DBU A;  2NWY A;  3MYQ A;  1ZSC A;  1G52 A;  1RZE A;  1DCB A;  2GEH A;  2NWZ A;  1CNH A;  3IBI A;  1H9N A;  1TTM A;  1G3Z A;  1CVD A;  3LXE A;  1CAO A;  1HEA A;  3HS4 A;  1CCS A;  2ZNC A;  1JV0 A;  1G53 A;  1CIM A;  3BL0 A;  1FSR A;  1IF9 A;  1G4J A;  1KEQ A;  12CA A;  1KOQ A;  2CBA A;  1Z97 A;  3M1J A;  3KON A;  1HUH A;  1UGB A;  2HL4 A;  1YO0 A;  3BET A;  3M40 A;  1RZD A;  9CA2 A;  2Q1B A;  3R17 B;  1BNQ A;  1IF6 A;  3B1B A;  2X7S A;  1AM6 A;  1FR4 A;  3PO6 A;  1CAJ A;  1RZA A;  1BIC A;  1CVH A;  2HOC A;  3HKN A;  3MDZ A;  2H15 A;  2CA2 A;  2ILI A;  2EZ7 A;  1A42 A;  1CIL A;  3M2N A;  1UGE A;  1BNU A;  1G46 A;  1ZNC A;  1UGA A;  2NWP A;  3DD0 A;  1CNW A;  1V9E A;  1G45 A;  1RAZ A;  3EFI A;  3M1Q A;  3PYK A;  2FMZ A;  2HKK A;  1FQN A;  2F14 A;  1FQM A;  1CAK A;  3IQK A;  5CAC A;  1CRM A;  3K2F A;  1CCU A;  3MNU A;  3R16 A;  1XEG A;  1IF8 A;  1CAM A;  1BNM A;  1I9N A;  1OQ5 A;  3OKV A;  1V9I C;  1JD0 A;  2WD3 A;  1BN4 A;  1HEB A;  2NNS A;  1RZC A;  3HKQ A;  2NN7 A;  1OKM A;  2POW A;  1G4O A;  3MHI A;  3HKU A;  2NN1 A;  3IAI A;  3DCS A;  3MHL A;  2CAB A;  1ZSB A;  1HUG A;  3IBN A;  1HEC A;  2CBC A;  1TEU X;  1I9Q A;  3D93 A;  1YDD A;  1TG3 A;  3MNJ A;  1G6V A;  2ABE A;  3NJ9 A;  2OSF A;  3MWO A;  1CZM A;  3L14 A;  1YO1 A;  1G1D A;  2FMG A;  1I8Z A;  1H4N A;  3KS3 A;  8CA2 A;  1LUG A;  2NXR A;  1ZSA A;  1BNV A; 
#chains in the KnotProt database with same CATH homology
 3MNI A;  4CA2 A;  3DVD A;  3DC9 A;  3KWA A;  1Y7W A;  3NI5 A;  3C7P A;  1I9O A;  2HFW A;  1DMY A;  1F2W A;  1CNC A;  1TH9 A;  1YDA A;  3D0N A;  2FOS A;  1FQR A;  1CNI A;  3MHC A;  1FR7 A;  2HFX A;  3M96 A;  1CIN A;  3N3J A;  3CAJ A;  4CAC A;  2POU A;  1CRA A;  3M2Y A;  2VVA X;  1FQL A;  1I9L A;  3ML5 A;  3F7B A;  2OSM A;  1YDB A;  2WEO A;  1BNN A;  3DC3 A;  2FOQ A;  1CAN A;  3JXG A;  1ZE8 A;  1CVF A;  3MMF A;  2FNK A;  2O4Z A;  1OKN A;  1FLJ A;  3JXH C;  2HFY A;  1CA2 A;  3BL1 A;  2WEG A;  1CAY A;  1RJ5 A;  3MNK A;  2Q38 A;  2X7U A;  3M5S A;  1CNJ A;  2HNC A;  3OIM A;  3D92 A;  2NXT A;  3M1W A;  3K7K A;  3M5T A;  2POV A;  2NNO A;  3DVC A;  3F7U A;  1HCB A;  1CCT A;  2AW1 A;  2HD6 A;  1CVC A;  3KKX A;  3IGP A;  1I90 A;  3ZNC A;  1G0E A;  1CNG A;  3M98 A;  2AX2 A;  2FNN A;  1CAH A;  1BZM A;  1FSQ A;  1RJ6 A;  1TE3 X;  1KWQ A;  2FOU A;  2CBB A;  3N2P A;  1MUA A;  1BV3 A;  3ML2 A;  7CA2 A;  2WEH A;  3D8W A;  1LG5 A;  2FW4 A;  1CVE A;  1EOU A;  3MHO A;  3DA2 A;  1URT A;  1BN3 A;  3DCC A;  3OKU A;  1CAL A;  3MNH A;  3DVB A;  1H9Q A;  3HLJ A;  1T9N A;  1HED A;  3KOK A;  2CBE A;  3N0N A;  1IF7 A;  1I91 A;  1AZM A;  1HVA A;  1UGF A;  1CVA A;  1G48 A;  2Q1Q A;  2X7T A;  1YO2 A;  1TBT X;  3F4X A;  1I9M A;  1LZV A;  3EFT A;  2GD8 A;  1KOP A;  2NNG A;  2EU2 A;  3IBU A;  3DCW A;  3M2Z A;  3M5E A;  3DAZ A;  3CA2 A;  1BN1 A;  1HCA A;  2FNM A;  1Z93 A;  2EU3 A;  1LG6 A;  1CAI A;  3K34 A;  1KWR A;  1IF4 A;  1THK A;  3FFP X;  1LGD A;  1I9P A;  3OIL A;  3MNA A;  1YDC A;  3CZV A;  2WEJ A;  3GZ0 A;  1CNY A;  3DV7 A;  6CA2 A;  1TG9 A;  1AVN A;  1G0F A;  2IT4 A;  3JXF A;  1BNT A;  1BNW A;  3P4V A;  2VVB X;  3KIG A;  3FE4 A;  3IBL A;  3OIK A;  3F8E A;  3IEO A;  1RZB A;  1XEV A;  1FSN A;  1BCD A;  1J9W A;  2NWO A;  3M3X A;  1CVB A;  1DCA A;  5CA2 A;  3B4F A;  1CNX A;  3D9Z A;  1CAZ A;  3MZC A;  3DD8 A;  2NXS A;  1XPZ A;  2W2J A;  3HKT A;  3FW3 A;  3N4B A;  1IF5 A;  2NMX A;  3HFP A;  1XQ0 A;  2CBD A;  2NNV A;  3MHM A;  1UGD A;  2WD2 A;  1CA3 A;  3M67 A;  1RAY A;  3DBU A;  2NWY A;  3MYQ A;  1ZSC A;  1G52 A;  1RZE A;  1DCB A;  2GEH A;  2NWZ A;  1CNH A;  3IBI A;  1H9N A;  1TTM A;  1G3Z A;  1CVD A;  3LXE A;  1CAO A;  1HEA A;  3HS4 A;  1CCS A;  2ZNC A;  1JV0 A;  1G53 A;  1CIM A;  3BL0 A;  1FSR A;  1IF9 A;  1G4J A;  1KEQ A;  12CA A;  1KOQ A;  2CBA A;  1Z97 A;  3M1J A;  3KON A;  1HUH A;  1UGB A;  2HL4 A;  1YO0 A;  3BET A;  3M40 A;  1RZD A;  9CA2 A;  2Q1B A;  3R17 B;  1BNQ A;  1IF6 A;  3B1B A;  2X7S A;  1AM6 A;  1FR4 A;  3PO6 A;  1CAJ A;  1RZA A;  1BIC A;  1CVH A;  2HOC A;  3HKN A;  3MDZ A;  2H15 A;  2CA2 A;  2ILI A;  2EZ7 A;  1A42 A;  1CIL A;  3M2N A;  1UGE A;  1BNU A;  1G46 A;  1ZNC A;  1UGA A;  2NWP A;  3DD0 A;  1CNW A;  1V9E A;  1G45 A;  1RAZ A;  3EFI A;  3M1Q A;  3PYK A;  2FMZ A;  2HKK A;  1FQN A;  2F14 A;  1FQM A;  1CAK A;  3IQK A;  5CAC A;  1CRM A;  3K2F A;  1CCU A;  3MNU A;  3R16 A;  1XEG A;  1IF8 A;  1CAM A;  1BNM A;  1I9N A;  1OQ5 A;  3OKV A;  1V9I C;  1JD0 A;  2WD3 A;  1BN4 A;  1HEB A;  2NNS A;  1RZC A;  3HKQ A;  2NN7 A;  1OKM A;  2POW A;  1G4O A;  3MHI A;  3HKU A;  2NN1 A;  3IAI A;  3DCS A;  3MHL A;  2CAB A;  1ZSB A;  1HUG A;  3IBN A;  1HEC A;  2CBC A;  1TEU X;  1I9Q A;  3D93 A;  1YDD A;  1TG3 A;  3MNJ A;  1G6V A;  2ABE A;  3NJ9 A;  2OSF A;  3MWO A;  1CZM A;  3L14 A;  1YO1 A;  1G1D A;  2FMG A;  1I8Z A;  1H4N A;  3KS3 A;  8CA2 A;  1LUG A;  2NXR A;  1ZSA A;  1BNV A;
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similar chains in the KnotProt database (?% sequence similarity)
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#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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