3HKUA

Human carbonic anhydrase ii in complex with topiramate
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 22-253 232 1-21, 254-257 21 4 knot
Chain Sequence
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 3x +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 24-253 230 254-257 1-1 2-23 1 3 slipknot
Fingerprint Knot forming loop Loop type
K +31 His4 ... His94 <->
Bridging ionZn261
<-> His96 ...
Chain closureLys260 <-> His4
probabilistic
K +31 His4 ... His96 <->
Bridging ionZn261
<-> His119 ...
Chain closureLys260 <-> His4
probabilistic
K +31 His4 ... His94 <->
Bridging ionZn261
<-> His119 ...
Chain closureLys260 <-> His4
probabilistic
Chain Sequence
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 25-256 232 1-24, 257-257 24 1 knot
view details
2.1 24-251 228 1-23 257-257 252-256 23 1 slipknot
sequence length 257
structure length 257
publication title S-Glycosyl Primary Sulfonamides-A New Structural Class for Selective Inhibition of Cancer-Associated Carbonic Anhydrases
doi rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
total genus Genus: 75
ec nomenclature ec 4.2.1.1: Carbonate dehydratase.
pdb deposition date 2009-05-25
KnotProt deposition date 2018-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00194 Carb_anhydrase Eukaryotic-type carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 3hkuA00
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 3hkuA00
2VVAX 1H9QA 1CNIA 3KOKA 1XPZA 1FQRA 1AZMA 3D9ZA 2FOUA 3DC9A 2X7SA 6CA2A 1CVCA 3DV7A 1BNWA 1URTA 2WEOA 2CBAA 1BZMA 1Z93A 1HEAA 3K2FA 2NWZA 3KS3A 2FNMA 1HCBA 1BN1A 1MUAA 1HEDA 3N4BA 3IEOA 3OKUA 1G48A 1TEUX 3KWAA 3IBUA 1CAZA 1FSQA 1CNJA 8CA2A 1EOUA 1I9LA 4CACA 3M1WA 3IAIA 3DCSA 1G0EA 1A42A 1FQNA 3CA2A 3N2PA 1I91A 2NN1A 1CZMA 2NN7A 1YDCA 1RJ6A 3DC3A 2IT4A 2NNGA 1RZDA 1CVBA 3DVBA 1I9PA 1CNGA 2NXRA 1G6VA 2HFYA 1G0FA 3MHOA 3KONA 1CILA 3MNAA 2NNSA 1ZE8A 3P4VA 3DVCA 1CCSA 1CANA 1CVEA 3MNJA 3ML5A 1TH9A 3IBIA 3LXEA 2HOCA 2X7UA 3F8EA 3FW3A 1DMYA 3JXFA 1TG3A 1TE3X 1CAYA 4CA2A 1YDAA 1CRMA 2Q38A 3IBNA 2EU2A 1G46A 3OKVA 1J9WA 1BICA 5CACA 4PYYA 1IF5A 2CBEA 3M2NA 1OKMA 3MZCA 2CABA 3DBUA 1CAJA 1CNYA 1TG9A 3EFIA 3PYKA 1V9EA 3IGPA 1UGEA 2NNVA 3L14A 1ZNCA 2POUA 1CALA 1I9MA 3HFPA 1CVDA 2H15A 3IBLA 3JXHC 1UGAA 1LG5A 1H9NA 1BNVA 3HKNA 3HS4A 1UGDA 1KOQA 3EFTA 1UGFA 1DCAA 3F4XA 2ZNCA 1CIMA 1RZBA 2NXTA 2W2JA 1CNXA 1IF9A 3M98A 1OKNA 1JD0A 2POVA 1BNTA 3M2ZA 3NJ9A 3M1JA 3MHLA 2NWYA 1YO2A 1THKA 3HKQA 1Y7WA 1F2WA 1G4JA 1BNMA 2CBCA 3M5EA 3B1BA 1FR7A 3D0NA 3CAJA 2HFXA 1ZSAA 1IF6A 2HFWA 3CZVA 3FE4A 1LUGA 5CA2A 3D92A 2HNCA 2HL4A 2GD8A 1YDBA 2FOQA 3DA2A 1Z97A 3C7PA 7CA2A 2AW1A 1TBTX 1HECA 2HD6A 3F7UA 3MHIA 3NI5A 3M5TA 2ILIA 3R16A 2OSMA 9CA2A 1I90A 2ABEA 3DCWA 12CAA 2NWOA 1CVHA 2FNNA 2GEHA 1KOPA 3K34A 3HKUA 1HCAA 3MWOA 1KEQA 2NMXA 1HEBA 3JXGA 1G1DA 1YO0A 1CNCA 1CAMA 1V9IC 1FR4A 1FSNA 1HUHA 1CA3A 1LZVA 3N0NA 3M3XA 1FLJA 3BETA 2FMGA 3OILA 1IF7A 3B4FA 2CA2A 1BN4A 2WD3A 1YO1A 3DCCA 1CAIA 1LGDA 1G53A 3MNHA 1G52A 1RZEA 3OIMA 1DCBA 1CCTA 2O4ZA 3MHCA 3ML2A 2VVBX 2WD2A 3MMFA 2WEHA 1TTMA 3KKXA 2AX2A 2F14A 3DD8A 3MYQA 1KWQA 3K7KA 2NNOA 3D93A 2FMZA 2EU3A 1CAKA 3BL1A 1BNUA 1RAYA 3GZ0A 1BV3A 1CAHA 3MNUA 1I9OA 1AM6A 3DAZA 1YDDA 1G3ZA 3M1QA 1FQLA 1RJ5A 3HKTA 3M2YA 2CBBA 2Q1BA 1CCUA 1FSRA 1IF4A 1CNWA 3M5SA 1CNHA 1KWRA 3KIGA 2FW4A 3D8WA 2CBDA 1ZSCA 3M40A 2EZ7A 1XQ0A 1LG6A 1HVAA 3HLJA 1BNQA 2FNKA 1G45A 3PO6A 1FQMA 1XEVA 1I9QA 1T9NA 1RZAA 1BNNA 3OIKA 2OSFA 1BN3A 2NXSA 3IQKA 1CINA 1BCDA 3DVDA 1CVAA 3MNKA 2HKKA 3M67A 3F7BA 2FOSA 1ZSBA 1CRAA 3FFPX 1IF8A 1HUGA 1CA2A 2X7TA 1I9NA 2Q1QA 3MHMA 3M96A 1H4NA 1RAZA 3MNIA 1RZCA 3DD0A 3MDZA 1AVNA 1XEGA 2WEJA 3BL0A 1UGBA 2POWA 3R17B 3N3JA 1CAOA 1JV0A 1CVFA 1OQ5A 1G4OA 2NWPA 1I8ZA 2WEGA 3ZNCA
chains in the KnotProt database with same CATH superfamily
2VVAX 1H9QA 1CNIA 3KOKA 1XPZA 1FQRA 1AZMA 3D9ZA 2FOUA 3DC9A 2X7SA 6CA2A 1CVCA 3DV7A 1BNWA 1URTA 2WEOA 2CBAA 1BZMA 1Z93A 1HEAA 3K2FA 2NWZA 3KS3A 2FNMA 1HCBA 1BN1A 1MUAA 1HEDA 3N4BA 3IEOA 3OKUA 1G48A 1TEUX 3KWAA 3IBUA 1CAZA 1FSQA 1CNJA 8CA2A 1EOUA 1I9LA 4CACA 3M1WA 3IAIA 3DCSA 1G0EA 1A42A 1FQNA 3CA2A 3N2PA 1I91A 2NN1A 1CZMA 2NN7A 1YDCA 1RJ6A 3DC3A 2IT4A 2NNGA 1RZDA 1CVBA 3DVBA 1I9PA 1CNGA 2NXRA 1G6VA 2HFYA 1G0FA 3MHOA 3KONA 1CILA 3MNAA 2NNSA 1ZE8A 3P4VA 3DVCA 1CCSA 1CANA 1CVEA 3MNJA 3ML5A 1TH9A 3IBIA 3LXEA 2HOCA 2X7UA 3F8EA 3FW3A 1DMYA 3JXFA 1TG3A 1TE3X 1CAYA 4CA2A 1YDAA 1CRMA 2Q38A 3IBNA 2EU2A 1G46A 3OKVA 1J9WA 1BICA 5CACA 4PYYA 1IF5A 2CBEA 3M2NA 1OKMA 3MZCA 2CABA 3DBUA 1CAJA 1CNYA 1TG9A 3EFIA 3PYKA 1V9EA 3IGPA 1UGEA 2NNVA 3L14A 1ZNCA 2POUA 1CALA 1I9MA 3HFPA 1CVDA 2H15A 3IBLA 3JXHC 1UGAA 1LG5A 1H9NA 1BNVA 3HKNA 3HS4A 1UGDA 1KOQA 3EFTA 1UGFA 1DCAA 3F4XA 2ZNCA 1CIMA 1RZBA 2NXTA 2W2JA 1CNXA 1IF9A 3M98A 1OKNA 1JD0A 2POVA 1BNTA 3M2ZA 3NJ9A 3M1JA 3MHLA 2NWYA 1YO2A 1THKA 3HKQA 1Y7WA 1F2WA 1G4JA 1BNMA 2CBCA 3M5EA 3B1BA 1FR7A 3D0NA 3CAJA 2HFXA 1ZSAA 1IF6A 2HFWA 3CZVA 3FE4A 1LUGA 5CA2A 3D92A 2HNCA 2HL4A 2GD8A 1YDBA 2FOQA 3DA2A 1Z97A 3C7PA 7CA2A 2AW1A 1TBTX 1HECA 2HD6A 3F7UA 3MHIA 3NI5A 3M5TA 2ILIA 3R16A 2OSMA 9CA2A 1I90A 2ABEA 3DCWA 12CAA 2NWOA 1CVHA 2FNNA 2GEHA 1KOPA 3K34A 3HKUA 1HCAA 3MWOA 1KEQA 2NMXA 1HEBA 3JXGA 1G1DA 1YO0A 1CNCA 1CAMA 1V9IC 1FR4A 1FSNA 1HUHA 1CA3A 1LZVA 3N0NA 3M3XA 1FLJA 3BETA 2FMGA 3OILA 1IF7A 3B4FA 2CA2A 1BN4A 2WD3A 1YO1A 3DCCA 1CAIA 1LGDA 1G53A 3MNHA 1G52A 1RZEA 3OIMA 1DCBA 1CCTA 2O4ZA 3MHCA 3ML2A 2VVBX 2WD2A 3MMFA 2WEHA 1TTMA 3KKXA 2AX2A 2F14A 3DD8A 3MYQA 1KWQA 3K7KA 2NNOA 3D93A 2FMZA 2EU3A 1CAKA 3BL1A 1BNUA 1RAYA 3GZ0A 1BV3A 1CAHA 3MNUA 1I9OA 1AM6A 3DAZA 1YDDA 1G3ZA 3M1QA 1FQLA 1RJ5A 3HKTA 3M2YA 2CBBA 2Q1BA 1CCUA 1FSRA 1IF4A 1CNWA 3M5SA 1CNHA 1KWRA 3KIGA 2FW4A 3D8WA 2CBDA 1ZSCA 3M40A 2EZ7A 1XQ0A 1LG6A 1HVAA 3HLJA 1BNQA 2FNKA 1G45A 3PO6A 1FQMA 1XEVA 1I9QA 1T9NA 1RZAA 1BNNA 3OIKA 2OSFA 1BN3A 2NXSA 3IQKA 1CINA 1BCDA 3DVDA 1CVAA 3MNKA 2HKKA 3M67A 3F7BA 2FOSA 1ZSBA 1CRAA 3FFPX 1IF8A 1HUGA 1CA2A 2X7TA 1I9NA 2Q1QA 3MHMA 3M96A 1H4NA 1RAZA 3MNIA 1RZCA 3DD0A 3MDZA 1AVNA 1XEGA 2WEJA 3BL0A 1UGBA 2POWA 3R17B 3N3JA 1CAOA 1JV0A 1CVFA 1OQ5A 1G4OA 2NWPA 1I8ZA 2WEGA 3ZNCA
chains in the KnotProt database with same CATH topology
2VVAX 1H9QA 1CNIA 3KOKA 1XPZA 1FQRA 1AZMA 3D9ZA 2FOUA 3DC9A 2X7SA 6CA2A 1CVCA 3DV7A 1BNWA 1URTA 2WEOA 2CBAA 1BZMA 1Z93A 1HEAA 3K2FA 2NWZA 3KS3A 2FNMA 1HCBA 1BN1A 1MUAA 1HEDA 3N4BA 3IEOA 3OKUA 1G48A 1TEUX 3KWAA 3IBUA 1CAZA 1FSQA 1CNJA 8CA2A 1EOUA 1I9LA 4CACA 3M1WA 3IAIA 3DCSA 1G0EA 1A42A 1FQNA 3CA2A 3N2PA 1I91A 2NN1A 1CZMA 2NN7A 1YDCA 1RJ6A 3DC3A 2IT4A 2NNGA 1RZDA 1CVBA 3DVBA 1I9PA 1CNGA 2NXRA 1G6VA 2HFYA 1G0FA 3MHOA 3KONA 1CILA 3MNAA 2NNSA 1ZE8A 3P4VA 3DVCA 1CCSA 1CANA 1CVEA 3MNJA 3ML5A 1TH9A 3IBIA 3LXEA 2HOCA 2X7UA 3F8EA 3FW3A 1DMYA 3JXFA 1TG3A 1TE3X 1CAYA 4CA2A 1YDAA 1CRMA 2Q38A 3IBNA 2EU2A 1G46A 3OKVA 1J9WA 1BICA 5CACA 1IF5A 2CBEA 3M2NA 1OKMA 3MZCA 2CABA 3DBUA 1CAJA 1CNYA 1TG9A 3EFIA 3PYKA 1V9EA 3IGPA 1UGEA 2NNVA 3L14A 1ZNCA 2POUA 1CALA 1I9MA 3HFPA 1CVDA 2H15A 3IBLA 3JXHC 1UGAA 1LG5A 1H9NA 1BNVA 3HKNA 3HS4A 1UGDA 1KOQA 3EFTA 1UGFA 1DCAA 3F4XA 2ZNCA 1CIMA 1RZBA 2NXTA 2W2JA 1CNXA 1IF9A 3M98A 1OKNA 1JD0A 2POVA 1BNTA 3M2ZA 3NJ9A 3M1JA 3MHLA 2NWYA 1YO2A 1THKA 3HKQA 1Y7WA 1F2WA 1G4JA 1BNMA 2CBCA 3M5EA 3B1BA 1FR7A 3D0NA 3CAJA 2HFXA 1ZSAA 1IF6A 2HFWA 3CZVA 3FE4A 1LUGA 5CA2A 3D92A 2HNCA 2HL4A 2GD8A 1YDBA 2FOQA 3DA2A 1Z97A 3C7PA 7CA2A 2AW1A 1TBTX 1HECA 2HD6A 3F7UA 3MHIA 3NI5A 3M5TA 2ILIA 3R16A 2OSMA 9CA2A 1I90A 2ABEA 3DCWA 12CAA 2NWOA 1CVHA 2FNNA 2GEHA 1KOPA 3K34A 3HKUA 1HCAA 3MWOA 1KEQA 2NMXA 1HEBA 3JXGA 1G1DA 1YO0A 1CNCA 1CAMA 1V9IC 1FR4A 1FSNA 1HUHA 1CA3A 1LZVA 3N0NA 3M3XA 1FLJA 3BETA 2FMGA 3OILA 1IF7A 3B4FA 2CA2A 1BN4A 2WD3A 1YO1A 3DCCA 1CAIA 1LGDA 1G53A 3MNHA 1G52A 1RZEA 3OIMA 1DCBA 1CCTA 2O4ZA 3MHCA 3ML2A 2VVBX 2WD2A 3MMFA 2WEHA 1TTMA 3KKXA 2AX2A 2F14A 3DD8A 3MYQA 1KWQA 3K7KA 2NNOA 3D93A 2FMZA 2EU3A 1CAKA 3BL1A 1BNUA 1RAYA 3GZ0A 1BV3A 1CAHA 3MNUA 1I9OA 1AM6A 3DAZA 1YDDA 1G3ZA 3M1QA 1FQLA 1RJ5A 3HKTA 3M2YA 2CBBA 2Q1BA 1CCUA 1FSRA 1IF4A 1CNWA 3M5SA 1CNHA 1KWRA 3KIGA 2FW4A 3D8WA 2CBDA 1ZSCA 3M40A 2EZ7A 1XQ0A 1LG6A 1HVAA 3HLJA 1BNQA 2FNKA 1G45A 3PO6A 1FQMA 1XEVA 1I9QA 1T9NA 1RZAA 1BNNA 3OIKA 2OSFA 1BN3A 2NXSA 3IQKA 1CINA 1BCDA 3DVDA 1CVAA 3MNKA 2HKKA 3M67A 3F7BA 2FOSA 1ZSBA 1CRAA 3FFPX 1IF8A 1HUGA 1CA2A 2X7TA 1I9NA 2Q1QA 3MHMA 3M96A 1H4NA 1RAZA 3MNIA 1RZCA 3DD0A 3MDZA 1AVNA 1XEGA 2WEJA 3BL0A 1UGBA 2POWA 3R17B 3N3JA 1CAOA 1JV0A 1CVFA 1OQ5A 1G4OA 2NWPA 1I8ZA 2WEGA 3ZNCA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 2VVA X;  1H9Q A;  1CNI A;  3KOK A;  1XPZ A;  1FQR A;  1AZM A;  3D9Z A;  2FOU A;  3DC9 A;  2X7S A;  6CA2 A;  1CVC A;  3DV7 A;  1BNW A;  1URT A;  2WEO A;  2CBA A;  1BZM A;  1Z93 A;  1HEA A;  3K2F A;  2NWZ A;  3KS3 A;  2FNM A;  1HCB A;  1BN1 A;  1MUA A;  1HED A;  3N4B A;  3IEO A;  3OKU A;  1G48 A;  1TEU X;  3KWA A;  3IBU A;  1CAZ A;  1FSQ A;  1CNJ A;  8CA2 A;  1EOU A;  1I9L A;  4CAC A;  3M1W A;  3IAI A;  3DCS A;  1G0E A;  1A42 A;  1FQN A;  3CA2 A;  3N2P A;  1I91 A;  2NN1 A;  1CZM A;  2NN7 A;  1YDC A;  1RJ6 A;  3DC3 A;  2IT4 A;  2NNG A;  1RZD A;  1CVB A;  3DVB A;  1I9P A;  1CNG A;  2NXR A;  1G6V A;  2HFY A;  1G0F A;  3MHO A;  3KON A;  1CIL A;  3MNA A;  2NNS A;  1ZE8 A;  3P4V A;  3DVC A;  1CCS A;  1CAN A;  1CVE A;  3MNJ A;  3ML5 A;  1TH9 A;  3IBI A;  3LXE A;  2HOC A;  2X7U A;  3F8E A;  3FW3 A;  1DMY A;  3JXF A;  1TG3 A;  1TE3 X;  1CAY A;  4CA2 A;  1YDA A;  1CRM A;  2Q38 A;  3IBN A;  2EU2 A;  1G46 A;  3OKV A;  1J9W A;  1BIC A;  5CAC A;  4PYY A;  1IF5 A;  2CBE A;  3M2N A;  1OKM A;  3MZC A;  2CAB A;  3DBU A;  1CAJ A;  1CNY A;  1TG9 A;  3EFI A;  3PYK A;  1V9E A;  3IGP A;  1UGE A;  2NNV A;  3L14 A;  1ZNC A;  2POU A;  1CAL A;  1I9M A;  3HFP A;  1CVD A;  2H15 A;  3IBL A;  3JXH C;  1UGA A;  1LG5 A;  1H9N A;  1BNV A;  3HKN A;  3HS4 A;  1UGD A;  1KOQ A;  3EFT A;  1UGF A;  1DCA A;  3F4X A;  2ZNC A;  1CIM A;  1RZB A;  2NXT A;  2W2J A;  1CNX A;  1IF9 A;  3M98 A;  1OKN A;  1JD0 A;  2POV A;  1BNT A;  3M2Z A;  3NJ9 A;  3M1J A;  3MHL A;  2NWY A;  1YO2 A;  1THK A;  3HKQ A;  1Y7W A;  1F2W A;  1G4J A;  1BNM A;  2CBC A;  3M5E A;  3B1B A;  1FR7 A;  3D0N A;  3CAJ A;  2HFX A;  1ZSA A;  1IF6 A;  2HFW A;  3CZV A;  3FE4 A;  1LUG A;  5CA2 A;  3D92 A;  2HNC A;  2HL4 A;  2GD8 A;  1YDB A;  2FOQ A;  3DA2 A;  1Z97 A;  3C7P A;  7CA2 A;  2AW1 A;  1TBT X;  1HEC A;  2HD6 A;  3F7U A;  3MHI A;  3NI5 A;  3M5T A;  2ILI A;  3R16 A;  2OSM A;  9CA2 A;  1I90 A;  2ABE A;  3DCW A;  12CA A;  2NWO A;  1CVH A;  2FNN A;  2GEH A;  1KOP A;  3K34 A;  3HKU A;  1HCA A;  3MWO A;  1KEQ A;  2NMX A;  1HEB A;  3JXG A;  1G1D A;  1YO0 A;  1CNC A;  1CAM A;  1V9I C;  1FR4 A;  1FSN A;  1HUH A;  1CA3 A;  1LZV A;  3N0N A;  3M3X A;  1FLJ A;  3BET A;  2FMG A;  3OIL A;  1IF7 A;  3B4F A;  2CA2 A;  1BN4 A;  2WD3 A;  1YO1 A;  3DCC A;  1CAI A;  1LGD A;  1G53 A;  3MNH A;  1G52 A;  1RZE A;  3OIM A;  1DCB A;  1CCT A;  2O4Z A;  3MHC A;  3ML2 A;  2VVB X;  2WD2 A;  3MMF A;  2WEH A;  1TTM A;  3KKX A;  2AX2 A;  2F14 A;  3DD8 A;  3MYQ A;  1KWQ A;  3K7K A;  2NNO A;  3D93 A;  2FMZ A;  2EU3 A;  1CAK A;  3BL1 A;  1BNU A;  1RAY A;  3GZ0 A;  1BV3 A;  1CAH A;  3MNU A;  1I9O A;  1AM6 A;  3DAZ A;  1YDD A;  1G3Z A;  3M1Q A;  1FQL A;  1RJ5 A;  3HKT A;  3M2Y A;  2CBB A;  2Q1B A;  1CCU A;  1FSR A;  1IF4 A;  1CNW A;  3M5S A;  1CNH A;  1KWR A;  3KIG A;  2FW4 A;  3D8W A;  2CBD A;  1ZSC A;  3M40 A;  2EZ7 A;  1XQ0 A;  1LG6 A;  1HVA A;  3HLJ A;  1BNQ A;  2FNK A;  1G45 A;  3PO6 A;  1FQM A;  1XEV A;  1I9Q A;  1T9N A;  1RZA A;  1BNN A;  3OIK A;  2OSF A;  1BN3 A;  2NXS A;  3IQK A;  1CIN A;  1BCD A;  3DVD A;  1CVA A;  3MNK A;  2HKK A;  3M67 A;  3F7B A;  2FOS A;  1ZSB A;  1CRA A;  3FFP X;  1IF8 A;  1HUG A;  1CA2 A;  2X7T A;  1I9N A;  2Q1Q A;  3MHM A;  3M96 A;  1H4N A;  1RAZ A;  3MNI A;  1RZC A;  3DD0 A;  3MDZ A;  1AVN A;  1XEG A;  2WEJ A;  3BL0 A;  1UGB A;  2POW A;  3R17 B;  3N3J A;  1CAO A;  1JV0 A;  1CVF A;  1OQ5 A;  1G4O A;  2NWP A;  1I8Z A;  2WEG A;  3ZNC A; 
#chains in the KnotProt database with same CATH topology
 2VVA X;  1H9Q A;  1CNI A;  3KOK A;  1XPZ A;  1FQR A;  1AZM A;  3D9Z A;  2FOU A;  3DC9 A;  2X7S A;  6CA2 A;  1CVC A;  3DV7 A;  1BNW A;  1URT A;  2WEO A;  2CBA A;  1BZM A;  1Z93 A;  1HEA A;  3K2F A;  2NWZ A;  3KS3 A;  2FNM A;  1HCB A;  1BN1 A;  1MUA A;  1HED A;  3N4B A;  3IEO A;  3OKU A;  1G48 A;  1TEU X;  3KWA A;  3IBU A;  1CAZ A;  1FSQ A;  1CNJ A;  8CA2 A;  1EOU A;  1I9L A;  4CAC A;  3M1W A;  3IAI A;  3DCS A;  1G0E A;  1A42 A;  1FQN A;  3CA2 A;  3N2P A;  1I91 A;  2NN1 A;  1CZM A;  2NN7 A;  1YDC A;  1RJ6 A;  3DC3 A;  2IT4 A;  2NNG A;  1RZD A;  1CVB A;  3DVB A;  1I9P A;  1CNG A;  2NXR A;  1G6V A;  2HFY A;  1G0F A;  3MHO A;  3KON A;  1CIL A;  3MNA A;  2NNS A;  1ZE8 A;  3P4V A;  3DVC A;  1CCS A;  1CAN A;  1CVE A;  3MNJ A;  3ML5 A;  1TH9 A;  3IBI A;  3LXE A;  2HOC A;  2X7U A;  3F8E A;  3FW3 A;  1DMY A;  3JXF A;  1TG3 A;  1TE3 X;  1CAY A;  4CA2 A;  1YDA A;  1CRM A;  2Q38 A;  3IBN A;  2EU2 A;  1G46 A;  3OKV A;  1J9W A;  1BIC A;  5CAC A;  4PYY A;  1IF5 A;  2CBE A;  3M2N A;  1OKM A;  3MZC A;  2CAB A;  3DBU A;  1CAJ A;  1CNY A;  1TG9 A;  3EFI A;  3PYK A;  1V9E A;  3IGP A;  1UGE A;  2NNV A;  3L14 A;  1ZNC A;  2POU A;  1CAL A;  1I9M A;  3HFP A;  1CVD A;  2H15 A;  3IBL A;  3JXH C;  1UGA A;  1LG5 A;  1H9N A;  1BNV A;  3HKN A;  3HS4 A;  1UGD A;  1KOQ A;  3EFT A;  1UGF A;  1DCA A;  3F4X A;  2ZNC A;  1CIM A;  1RZB A;  2NXT A;  2W2J A;  1CNX A;  1IF9 A;  3M98 A;  1OKN A;  1JD0 A;  2POV A;  1BNT A;  3M2Z A;  3NJ9 A;  3M1J A;  3MHL A;  2NWY A;  1YO2 A;  1THK A;  3HKQ A;  1Y7W A;  1F2W A;  1G4J A;  1BNM A;  2CBC A;  3M5E A;  3B1B A;  1FR7 A;  3D0N A;  3CAJ A;  2HFX A;  1ZSA A;  1IF6 A;  2HFW A;  3CZV A;  3FE4 A;  1LUG A;  5CA2 A;  3D92 A;  2HNC A;  2HL4 A;  2GD8 A;  1YDB A;  2FOQ A;  3DA2 A;  1Z97 A;  3C7P A;  7CA2 A;  2AW1 A;  1TBT X;  1HEC A;  2HD6 A;  3F7U A;  3MHI A;  3NI5 A;  3M5T A;  2ILI A;  3R16 A;  2OSM A;  9CA2 A;  1I90 A;  2ABE A;  3DCW A;  12CA A;  2NWO A;  1CVH A;  2FNN A;  2GEH A;  1KOP A;  3K34 A;  3HKU A;  1HCA A;  3MWO A;  1KEQ A;  2NMX A;  1HEB A;  3JXG A;  1G1D A;  1YO0 A;  1CNC A;  1CAM A;  1V9I C;  1FR4 A;  1FSN A;  1HUH A;  1CA3 A;  1LZV A;  3N0N A;  3M3X A;  1FLJ A;  3BET A;  2FMG A;  3OIL A;  1IF7 A;  3B4F A;  2CA2 A;  1BN4 A;  2WD3 A;  1YO1 A;  3DCC A;  1CAI A;  1LGD A;  1G53 A;  3MNH A;  1G52 A;  1RZE A;  3OIM A;  1DCB A;  1CCT A;  2O4Z A;  3MHC A;  3ML2 A;  2VVB X;  2WD2 A;  3MMF A;  2WEH A;  1TTM A;  3KKX A;  2AX2 A;  2F14 A;  3DD8 A;  3MYQ A;  1KWQ A;  3K7K A;  2NNO A;  3D93 A;  2FMZ A;  2EU3 A;  1CAK A;  3BL1 A;  1BNU A;  1RAY A;  3GZ0 A;  1BV3 A;  1CAH A;  3MNU A;  1I9O A;  1AM6 A;  3DAZ A;  1YDD A;  1G3Z A;  3M1Q A;  1FQL A;  1RJ5 A;  3HKT A;  3M2Y A;  2CBB A;  2Q1B A;  1CCU A;  1FSR A;  1IF4 A;  1CNW A;  3M5S A;  1CNH A;  1KWR A;  3KIG A;  2FW4 A;  3D8W A;  2CBD A;  1ZSC A;  3M40 A;  2EZ7 A;  1XQ0 A;  1LG6 A;  1HVA A;  3HLJ A;  1BNQ A;  2FNK A;  1G45 A;  3PO6 A;  1FQM A;  1XEV A;  1I9Q A;  1T9N A;  1RZA A;  1BNN A;  3OIK A;  2OSF A;  1BN3 A;  2NXS A;  3IQK A;  1CIN A;  1BCD A;  3DVD A;  1CVA A;  3MNK A;  2HKK A;  3M67 A;  3F7B A;  2FOS A;  1ZSB A;  1CRA A;  3FFP X;  1IF8 A;  1HUG A;  1CA2 A;  2X7T A;  1I9N A;  2Q1Q A;  3MHM A;  3M96 A;  1H4N A;  1RAZ A;  3MNI A;  1RZC A;  3DD0 A;  3MDZ A;  1AVN A;  1XEG A;  2WEJ A;  3BL0 A;  1UGB A;  2POW A;  3R17 B;  3N3J A;  1CAO A;  1JV0 A;  1CVF A;  1OQ5 A;  1G4O A;  2NWP A;  1I8Z A;  2WEG A;  3ZNC A; 
#chains in the KnotProt database with same CATH homology
 2VVA X;  1H9Q A;  1CNI A;  3KOK A;  1XPZ A;  1FQR A;  1AZM A;  3D9Z A;  2FOU A;  3DC9 A;  2X7S A;  6CA2 A;  1CVC A;  3DV7 A;  1BNW A;  1URT A;  2WEO A;  2CBA A;  1BZM A;  1Z93 A;  1HEA A;  3K2F A;  2NWZ A;  3KS3 A;  2FNM A;  1HCB A;  1BN1 A;  1MUA A;  1HED A;  3N4B A;  3IEO A;  3OKU A;  1G48 A;  1TEU X;  3KWA A;  3IBU A;  1CAZ A;  1FSQ A;  1CNJ A;  8CA2 A;  1EOU A;  1I9L A;  4CAC A;  3M1W A;  3IAI A;  3DCS A;  1G0E A;  1A42 A;  1FQN A;  3CA2 A;  3N2P A;  1I91 A;  2NN1 A;  1CZM A;  2NN7 A;  1YDC A;  1RJ6 A;  3DC3 A;  2IT4 A;  2NNG A;  1RZD A;  1CVB A;  3DVB A;  1I9P A;  1CNG A;  2NXR A;  1G6V A;  2HFY A;  1G0F A;  3MHO A;  3KON A;  1CIL A;  3MNA A;  2NNS A;  1ZE8 A;  3P4V A;  3DVC A;  1CCS A;  1CAN A;  1CVE A;  3MNJ A;  3ML5 A;  1TH9 A;  3IBI A;  3LXE A;  2HOC A;  2X7U A;  3F8E A;  3FW3 A;  1DMY A;  3JXF A;  1TG3 A;  1TE3 X;  1CAY A;  4CA2 A;  1YDA A;  1CRM A;  2Q38 A;  3IBN A;  2EU2 A;  1G46 A;  3OKV A;  1J9W A;  1BIC A;  5CAC A;  1IF5 A;  2CBE A;  3M2N A;  1OKM A;  3MZC A;  2CAB A;  3DBU A;  1CAJ A;  1CNY A;  1TG9 A;  3EFI A;  3PYK A;  1V9E A;  3IGP A;  1UGE A;  2NNV A;  3L14 A;  1ZNC A;  2POU A;  1CAL A;  1I9M A;  3HFP A;  1CVD A;  2H15 A;  3IBL A;  3JXH C;  1UGA A;  1LG5 A;  1H9N A;  1BNV A;  3HKN A;  3HS4 A;  1UGD A;  1KOQ A;  3EFT A;  1UGF A;  1DCA A;  3F4X A;  2ZNC A;  1CIM A;  1RZB A;  2NXT A;  2W2J A;  1CNX A;  1IF9 A;  3M98 A;  1OKN A;  1JD0 A;  2POV A;  1BNT A;  3M2Z A;  3NJ9 A;  3M1J A;  3MHL A;  2NWY A;  1YO2 A;  1THK A;  3HKQ A;  1Y7W A;  1F2W A;  1G4J A;  1BNM A;  2CBC A;  3M5E A;  3B1B A;  1FR7 A;  3D0N A;  3CAJ A;  2HFX A;  1ZSA A;  1IF6 A;  2HFW A;  3CZV A;  3FE4 A;  1LUG A;  5CA2 A;  3D92 A;  2HNC A;  2HL4 A;  2GD8 A;  1YDB A;  2FOQ A;  3DA2 A;  1Z97 A;  3C7P A;  7CA2 A;  2AW1 A;  1TBT X;  1HEC A;  2HD6 A;  3F7U A;  3MHI A;  3NI5 A;  3M5T A;  2ILI A;  3R16 A;  2OSM A;  9CA2 A;  1I90 A;  2ABE A;  3DCW A;  12CA A;  2NWO A;  1CVH A;  2FNN A;  2GEH A;  1KOP A;  3K34 A;  3HKU A;  1HCA A;  3MWO A;  1KEQ A;  2NMX A;  1HEB A;  3JXG A;  1G1D A;  1YO0 A;  1CNC A;  1CAM A;  1V9I C;  1FR4 A;  1FSN A;  1HUH A;  1CA3 A;  1LZV A;  3N0N A;  3M3X A;  1FLJ A;  3BET A;  2FMG A;  3OIL A;  1IF7 A;  3B4F A;  2CA2 A;  1BN4 A;  2WD3 A;  1YO1 A;  3DCC A;  1CAI A;  1LGD A;  1G53 A;  3MNH A;  1G52 A;  1RZE A;  3OIM A;  1DCB A;  1CCT A;  2O4Z A;  3MHC A;  3ML2 A;  2VVB X;  2WD2 A;  3MMF A;  2WEH A;  1TTM A;  3KKX A;  2AX2 A;  2F14 A;  3DD8 A;  3MYQ A;  1KWQ A;  3K7K A;  2NNO A;  3D93 A;  2FMZ A;  2EU3 A;  1CAK A;  3BL1 A;  1BNU A;  1RAY A;  3GZ0 A;  1BV3 A;  1CAH A;  3MNU A;  1I9O A;  1AM6 A;  3DAZ A;  1YDD A;  1G3Z A;  3M1Q A;  1FQL A;  1RJ5 A;  3HKT A;  3M2Y A;  2CBB A;  2Q1B A;  1CCU A;  1FSR A;  1IF4 A;  1CNW A;  3M5S A;  1CNH A;  1KWR A;  3KIG A;  2FW4 A;  3D8W A;  2CBD A;  1ZSC A;  3M40 A;  2EZ7 A;  1XQ0 A;  1LG6 A;  1HVA A;  3HLJ A;  1BNQ A;  2FNK A;  1G45 A;  3PO6 A;  1FQM A;  1XEV A;  1I9Q A;  1T9N A;  1RZA A;  1BNN A;  3OIK A;  2OSF A;  1BN3 A;  2NXS A;  3IQK A;  1CIN A;  1BCD A;  3DVD A;  1CVA A;  3MNK A;  2HKK A;  3M67 A;  3F7B A;  2FOS A;  1ZSB A;  1CRA A;  3FFP X;  1IF8 A;  1HUG A;  1CA2 A;  2X7T A;  1I9N A;  2Q1Q A;  3MHM A;  3M96 A;  1H4N A;  1RAZ A;  3MNI A;  1RZC A;  3DD0 A;  3MDZ A;  1AVN A;  1XEG A;  2WEJ A;  3BL0 A;  1UGB A;  2POW A;  3R17 B;  3N3J A;  1CAO A;  1JV0 A;  1CVF A;  1OQ5 A;  1G4O A;  2NWP A;  1I8Z A;  2WEG A;  3ZNC A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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