2NNOA

Structure of inhibitor binding to carbonic anhydrase ii
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 76
Alphaknot: P00918
Knot K +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 26-256 231 1-25, 257-260 25 4 knot
Chain Sequence
SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLE-VTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 3x +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 24-256 233 1-23, 257-260 23 4 knot
Fingerprint Knot forming loop Loop type
K +31
Chain closureSer2 <-> Lys261
... His96 <->
Bridging ionZn262
<-> His94 ... Ser2		 probabilistic
K +31 Ser2 ... His96 <->
Bridging ionZn262
<-> His119 ...
Chain closureLys261 <-> Ser2
 probabilistic
K +31 Ser2 ... His94 <->
Bridging ionZn262
<-> His119 ...
Chain closureLys261 <-> Ser2
 probabilistic
Chain Sequence
SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLE-VTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 27-257 231 1-26, 258-259 26 2 knot
view details
2.1 26-253 228 1-25 258-259 254-257 25 2 slipknot
sequence length 259
structure length 258
publication title Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
pubmed doi rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
missing residues 204
total genus Genus: 76
ec nomenclature ec 4.2.1.1: Carbonate dehydratase.
pdb deposition date 2006-10-24
KnotProt deposition date 2018-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00194 Carb_anhydrase Eukaryotic-type carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 2nnoA00
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 2nnoA00
2NXRA 2NXTA 1CCSA 3MNUA 1BN3A 1HVAA 3DCCA 2WEOA 2FMGA 1CNGA 3DV7A 3N2PA 2WEHA 1IF8A 2F14A 2NN7A 12CAA 1ZE8A 3KKXA 2NN1A 3IQKA 3HFPA 1FQNA 1HEDA 1G4JA 1CILA 1BNVA 3NI5A 1ZNCA 2HL4A 2VVAX 1HCAA 1CVHA 1RJ5A 1CNYA 1T9NA 3L14A 6CA2A 3DVCA 1CVDA 1J9WA 3B4FA 1KEQA 1YO2A 1IF4A 1Y7WA 2WD2A 1CINA 1V9EA 3MNIA 3M3XA 3FW3A 1TE3X 3D92A 1RJ6A 3DVDA 2X7UA 1CAKA 3PYKA 1OKNA 1I9QA 1BV3A 1TTMA 3D0NA 1RZDA 3DD0A 5CACA 1IF7A 3ML5A 2CBEA 3M5EA 2FNNA 7CA2A 1CANA 2AX2A 1KWRA 2NWZA 1Z97A 1LZVA 3R17B 3OKVA 3OILA 2NWYA 1CAIA 1IF5A 3MHLA 1FSNA 1CNIA 3MHCA 2NNGA 1UGFA 1CAHA 1FQMA 3FE4A 1RZEA 3MHIA 1DCAA 2GEHA 2Q1BA 3DCSA 2Q1QA 1HUGA 3EFTA 2CBBA 1RAZA 3MNKA 3IBIA 3IGPA 1YDCA 2NWPA 1H9NA 2FNKA 3OIMA 3F7UA 3D93A 3F7BA 1RZAA 2Q38A 1F2WA 3D9ZA 4CA2A 1CAOA 3ZNCA 4CACA 1RZCA 1CAZA 3M2ZA 3MHMA 3IBUA 8CA2A 1G6VA 3NJ9A 2FOSA 1BNUA 2O4ZA 1G53A 2POWA 1I90A 2ILIA 1TG3A 3M5TA 3M1WA 3BL0A 1I91A 1XQ0A 1FQRA 3BETA 1ZSCA 2FW4A 1G4OA 1YO1A 3MWOA 2FMZA 1RZBA 3LXEA 1BZMA 1BCDA 1CNHA 1FSQA 1H4NA 1Z93A 1BNQA 3KS3A 3CAJA 1I9PA 2AW1A 1G52A 1OKMA 2W2JA 2NMXA 1KOQA 1BNMA 1CAMA 1URTA 1MUAA 3CZVA 3DVBA 3M2NA 3DAZA 3M1QA 1LG5A 1CIMA 3EFIA 2NNOA 1BNWA 2FOQA 2WD3A 1XEGA 2IT4A 1UGBA 2EZ7A 3K2FA 4PYYA 2NNSA 3DCWA 3MNJA 3HS4A 3IAIA 1CVAA 3IEOA 3F4XA 1LUGA 1BICA 1HEAA 3JXHC 2POVA 1CCTA 1TEUX 2HFXA 1G48A 1JD0A 2HNCA 1ZSBA 3R16A 3MNHA 1HEBA 3F8EA 2OSFA 1TG9A 1CVCA 1AZMA 1G45A 2NNVA 2POUA 2CA2A 3OKUA 1LG6A 3IBLA 3DD8A 2HOCA 3DC9A 3IBNA 2HFWA 1ZSAA 1AM6A 3M96A 3PO6A 3KWAA 1CNCA 1CRAA 1KOPA 1XEVA 1JV0A 3DBUA 3P4VA 1RAYA 2ABEA 3OIKA 2H15A 1FR4A 1I9OA 3M40A 1CAJA 2X7SA 1XPZA 3N0NA 3DA2A 1YO0A 2CBDA 3BL1A 3HKUA 2HKKA 2CABA 2FOUA 3C7PA 3HLJA 1AVNA 1CALA 1BNNA 1FSRA 1LGDA 3D8WA 3M98A 1IF6A 1UGAA 3MDZA 1HUHA 2X7TA 1FR7A 2EU2A 3M2YA 2VVBX 2GD8A 1KWQA 1CZMA 3JXGA 3KOKA 3M1JA 1CCUA 1G1DA 1CNWA 1THKA 1UGDA 1DMYA 2WEGA 3JXFA 1V9IC 2HD6A 1YDBA 2FNMA 1TH9A 2NWOA 2OSMA 3MMFA 3GZ0A 1UGEA 2CBAA 1CVBA 3HKNA 1A42A 1CNXA 3DC3A 1CVFA 9CA2A 1G46A 1YDAA 3K34A 3HKTA 1CRMA 1H9QA 1CA2A 1IF9A 3N4BA 3MZCA 1BNTA 3MNAA 1FLJA 1G0EA 3N3JA 1FQLA 3B1BA 1CNJA 1HCBA 1HECA 1DCBA 1I9LA 3ML2A 1CA3A 2ZNCA 3KIGA 1I8ZA 2WEJA 3HKQA 5CA2A 1BN1A 1OQ5A 2NXSA 3M5SA 3M67A 3MHOA 3MYQA 1TBTX 1YDDA 1CVEA 3FFPX 1G0FA 1BN4A 2HFYA 3K7KA 3KONA 1I9NA 2CBCA 3CA2A 1EOUA 1G3ZA 2EU3A 1I9MA 1CAYA
chains in the KnotProt database with same CATH superfamily
2NXRA 2NXTA 1CCSA 3MNUA 1BN3A 1HVAA 3DCCA 2WEOA 2FMGA 1CNGA 3DV7A 3N2PA 2WEHA 1IF8A 2F14A 2NN7A 12CAA 1ZE8A 3KKXA 2NN1A 3IQKA 3HFPA 1FQNA 1HEDA 1G4JA 1CILA 1BNVA 3NI5A 1ZNCA 2HL4A 2VVAX 1HCAA 1CVHA 1RJ5A 1CNYA 1T9NA 3L14A 6CA2A 3DVCA 1CVDA 1J9WA 3B4FA 1KEQA 1YO2A 1IF4A 1Y7WA 2WD2A 1CINA 1V9EA 3MNIA 3M3XA 3FW3A 1TE3X 3D92A 1RJ6A 3DVDA 2X7UA 1CAKA 3PYKA 1OKNA 1I9QA 1BV3A 1TTMA 3D0NA 1RZDA 3DD0A 5CACA 1IF7A 3ML5A 2CBEA 3M5EA 2FNNA 7CA2A 1CANA 2AX2A 1KWRA 2NWZA 1Z97A 1LZVA 3R17B 3OKVA 3OILA 2NWYA 1CAIA 1IF5A 3MHLA 1FSNA 1CNIA 3MHCA 2NNGA 1UGFA 1CAHA 1FQMA 3FE4A 1RZEA 3MHIA 1DCAA 2GEHA 2Q1BA 3DCSA 2Q1QA 1HUGA 3EFTA 2CBBA 1RAZA 3MNKA 3IBIA 3IGPA 1YDCA 2NWPA 1H9NA 2FNKA 3OIMA 3F7UA 3D93A 3F7BA 1RZAA 2Q38A 1F2WA 3D9ZA 4CA2A 1CAOA 3ZNCA 4CACA 1RZCA 1CAZA 3M2ZA 3MHMA 3IBUA 8CA2A 1G6VA 3NJ9A 2FOSA 1BNUA 2O4ZA 1G53A 2POWA 1I90A 2ILIA 1TG3A 3M5TA 3M1WA 3BL0A 1I91A 1XQ0A 1FQRA 3BETA 1ZSCA 2FW4A 1G4OA 1YO1A 3MWOA 2FMZA 1RZBA 3LXEA 1BZMA 1BCDA 1CNHA 1FSQA 1H4NA 1Z93A 1BNQA 3KS3A 3CAJA 1I9PA 2AW1A 1G52A 1OKMA 2W2JA 2NMXA 1KOQA 1BNMA 1CAMA 1URTA 1MUAA 3CZVA 3DVBA 3M2NA 3DAZA 3M1QA 1LG5A 1CIMA 3EFIA 2NNOA 1BNWA 2FOQA 2WD3A 1XEGA 2IT4A 1UGBA 2EZ7A 3K2FA 4PYYA 2NNSA 3DCWA 3MNJA 3HS4A 3IAIA 1CVAA 3IEOA 3F4XA 1LUGA 1BICA 1HEAA 3JXHC 2POVA 1CCTA 1TEUX 2HFXA 1G48A 1JD0A 2HNCA 1ZSBA 3R16A 3MNHA 1HEBA 3F8EA 2OSFA 1TG9A 1CVCA 1AZMA 1G45A 2NNVA 2POUA 2CA2A 3OKUA 1LG6A 3IBLA 3DD8A 2HOCA 3DC9A 3IBNA 2HFWA 1ZSAA 1AM6A 3M96A 3PO6A 3KWAA 1CNCA 1CRAA 1KOPA 1XEVA 1JV0A 3DBUA 3P4VA 1RAYA 2ABEA 3OIKA 2H15A 1FR4A 1I9OA 3M40A 1CAJA 2X7SA 1XPZA 3N0NA 3DA2A 1YO0A 2CBDA 3BL1A 3HKUA 2HKKA 2CABA 2FOUA 3C7PA 3HLJA 1AVNA 1CALA 1BNNA 1FSRA 1LGDA 3D8WA 3M98A 1IF6A 1UGAA 3MDZA 1HUHA 2X7TA 1FR7A 2EU2A 3M2YA 2VVBX 2GD8A 1KWQA 1CZMA 3JXGA 3KOKA 3M1JA 1CCUA 1G1DA 1CNWA 1THKA 1UGDA 1DMYA 2WEGA 3JXFA 1V9IC 2HD6A 1YDBA 2FNMA 1TH9A 2NWOA 2OSMA 3MMFA 3GZ0A 1UGEA 2CBAA 1CVBA 3HKNA 1A42A 1CNXA 3DC3A 1CVFA 9CA2A 1G46A 1YDAA 3K34A 3HKTA 1CRMA 1H9QA 1CA2A 1IF9A 3N4BA 3MZCA 1BNTA 3MNAA 1FLJA 1G0EA 3N3JA 1FQLA 3B1BA 1CNJA 1HCBA 1HECA 1DCBA 1I9LA 3ML2A 1CA3A 2ZNCA 3KIGA 1I8ZA 2WEJA 3HKQA 5CA2A 1BN1A 1OQ5A 2NXSA 3M5SA 3M67A 3MHOA 3MYQA 1TBTX 1YDDA 1CVEA 3FFPX 1G0FA 1BN4A 2HFYA 3K7KA 3KONA 1I9NA 2CBCA 3CA2A 1EOUA 1G3ZA 2EU3A 1I9MA 1CAYA
chains in the KnotProt database with same CATH topology
2NXRA 2NXTA 1CCSA 3MNUA 1BN3A 1HVAA 3DCCA 2WEOA 2FMGA 1CNGA 3DV7A 3N2PA 2WEHA 1IF8A 2F14A 2NN7A 12CAA 1ZE8A 3KKXA 2NN1A 3IQKA 3HFPA 1FQNA 1HEDA 1G4JA 1CILA 1BNVA 3NI5A 1ZNCA 2HL4A 2VVAX 1HCAA 1CVHA 1RJ5A 1CNYA 1T9NA 3L14A 6CA2A 3DVCA 1CVDA 1J9WA 3B4FA 1KEQA 1YO2A 1IF4A 1Y7WA 2WD2A 1CINA 1V9EA 3MNIA 3M3XA 3FW3A 1TE3X 3D92A 1RJ6A 3DVDA 2X7UA 1CAKA 3PYKA 1OKNA 1I9QA 1BV3A 1TTMA 3D0NA 1RZDA 3DD0A 5CACA 1IF7A 3ML5A 2CBEA 3M5EA 2FNNA 7CA2A 1CANA 2AX2A 1KWRA 2NWZA 1Z97A 1LZVA 3R17B 3OKVA 3OILA 2NWYA 1CAIA 1IF5A 3MHLA 1FSNA 1CNIA 3MHCA 2NNGA 1UGFA 1CAHA 1FQMA 3FE4A 1RZEA 3MHIA 1DCAA 2GEHA 2Q1BA 3DCSA 2Q1QA 1HUGA 3EFTA 2CBBA 1RAZA 3MNKA 3IBIA 3IGPA 1YDCA 2NWPA 1H9NA 2FNKA 3OIMA 3F7UA 3D93A 3F7BA 1RZAA 2Q38A 1F2WA 3D9ZA 4CA2A 1CAOA 3ZNCA 4CACA 1RZCA 1CAZA 3M2ZA 3MHMA 3IBUA 8CA2A 1G6VA 3NJ9A 2FOSA 1BNUA 2O4ZA 1G53A 2POWA 1I90A 2ILIA 1TG3A 3M5TA 3M1WA 3BL0A 1I91A 1XQ0A 1FQRA 3BETA 1ZSCA 2FW4A 1G4OA 1YO1A 3MWOA 2FMZA 1RZBA 3LXEA 1BZMA 1BCDA 1CNHA 1FSQA 1H4NA 1Z93A 1BNQA 3KS3A 3CAJA 1I9PA 2AW1A 1G52A 1OKMA 2W2JA 2NMXA 1KOQA 1BNMA 1CAMA 1URTA 1MUAA 3CZVA 3DVBA 3M2NA 3DAZA 3M1QA 1LG5A 1CIMA 3EFIA 2NNOA 1BNWA 2FOQA 2WD3A 1XEGA 2IT4A 1UGBA 2EZ7A 3K2FA 2NNSA 3DCWA 3MNJA 3HS4A 3IAIA 1CVAA 3IEOA 3F4XA 1LUGA 1BICA 1HEAA 3JXHC 2POVA 1CCTA 1TEUX 2HFXA 1G48A 1JD0A 2HNCA 1ZSBA 3R16A 3MNHA 1HEBA 3F8EA 2OSFA 1TG9A 1CVCA 1AZMA 1G45A 2NNVA 2POUA 2CA2A 3OKUA 1LG6A 3IBLA 3DD8A 2HOCA 3DC9A 3IBNA 2HFWA 1ZSAA 1AM6A 3M96A 3PO6A 3KWAA 1CNCA 1CRAA 1KOPA 1XEVA 1JV0A 3DBUA 3P4VA 1RAYA 2ABEA 3OIKA 2H15A 1FR4A 1I9OA 3M40A 1CAJA 2X7SA 1XPZA 3N0NA 3DA2A 1YO0A 2CBDA 3BL1A 3HKUA 2HKKA 2CABA 2FOUA 3C7PA 3HLJA 1AVNA 1CALA 1BNNA 1FSRA 1LGDA 3D8WA 3M98A 1IF6A 1UGAA 3MDZA 1HUHA 2X7TA 1FR7A 2EU2A 3M2YA 2VVBX 2GD8A 1KWQA 1CZMA 3JXGA 3KOKA 3M1JA 1CCUA 1G1DA 1CNWA 1THKA 1UGDA 1DMYA 2WEGA 3JXFA 1V9IC 2HD6A 1YDBA 2FNMA 1TH9A 2NWOA 2OSMA 3MMFA 3GZ0A 1UGEA 2CBAA 1CVBA 3HKNA 1A42A 1CNXA 3DC3A 1CVFA 9CA2A 1G46A 1YDAA 3K34A 3HKTA 1CRMA 1H9QA 1CA2A 1IF9A 3N4BA 3MZCA 1BNTA 3MNAA 1FLJA 1G0EA 3N3JA 1FQLA 3B1BA 1CNJA 1HCBA 1HECA 1DCBA 1I9LA 3ML2A 1CA3A 2ZNCA 3KIGA 1I8ZA 2WEJA 3HKQA 5CA2A 1BN1A 1OQ5A 2NXSA 3M5SA 3M67A 3MHOA 3MYQA 1TBTX 1YDDA 1CVEA 3FFPX 1G0FA 1BN4A 2HFYA 3K7KA 3KONA 1I9NA 2CBCA 3CA2A 1EOUA 1G3ZA 2EU3A 1I9MA 1CAYA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 2NXR A;  2NXT A;  1CCS A;  3MNU A;  1BN3 A;  1HVA A;  3DCC A;  2WEO A;  2FMG A;  1CNG A;  3DV7 A;  3N2P A;  2WEH A;  1IF8 A;  2F14 A;  2NN7 A;  12CA A;  1ZE8 A;  3KKX A;  2NN1 A;  3IQK A;  3HFP A;  1FQN A;  1HED A;  1G4J A;  1CIL A;  1BNV A;  3NI5 A;  1ZNC A;  2HL4 A;  2VVA X;  1HCA A;  1CVH A;  1RJ5 A;  1CNY A;  1T9N A;  3L14 A;  6CA2 A;  3DVC A;  1CVD A;  1J9W A;  3B4F A;  1KEQ A;  1YO2 A;  1IF4 A;  1Y7W A;  2WD2 A;  1CIN A;  1V9E A;  3MNI A;  3M3X A;  3FW3 A;  1TE3 X;  3D92 A;  1RJ6 A;  3DVD A;  2X7U A;  1CAK A;  3PYK A;  1OKN A;  1I9Q A;  1BV3 A;  1TTM A;  3D0N A;  1RZD A;  3DD0 A;  5CAC A;  1IF7 A;  3ML5 A;  2CBE A;  3M5E A;  2FNN A;  7CA2 A;  1CAN A;  2AX2 A;  1KWR A;  2NWZ A;  1Z97 A;  1LZV A;  3R17 B;  3OKV A;  3OIL A;  2NWY A;  1CAI A;  1IF5 A;  3MHL A;  1FSN A;  1CNI A;  3MHC A;  2NNG A;  1UGF A;  1CAH A;  1FQM A;  3FE4 A;  1RZE A;  3MHI A;  1DCA A;  2GEH A;  2Q1B A;  3DCS A;  2Q1Q A;  1HUG A;  3EFT A;  2CBB A;  1RAZ A;  3MNK A;  3IBI A;  3IGP A;  1YDC A;  2NWP A;  1H9N A;  2FNK A;  3OIM A;  3F7U A;  3D93 A;  3F7B A;  1RZA A;  2Q38 A;  1F2W A;  3D9Z A;  4CA2 A;  1CAO A;  3ZNC A;  4CAC A;  1RZC A;  1CAZ A;  3M2Z A;  3MHM A;  3IBU A;  8CA2 A;  1G6V A;  3NJ9 A;  2FOS A;  1BNU A;  2O4Z A;  1G53 A;  2POW A;  1I90 A;  2ILI A;  1TG3 A;  3M5T A;  3M1W A;  3BL0 A;  1I91 A;  1XQ0 A;  1FQR A;  3BET A;  1ZSC A;  2FW4 A;  1G4O A;  1YO1 A;  3MWO A;  2FMZ A;  1RZB A;  3LXE A;  1BZM A;  1BCD A;  1CNH A;  1FSQ A;  1H4N A;  1Z93 A;  1BNQ A;  3KS3 A;  3CAJ A;  1I9P A;  2AW1 A;  1G52 A;  1OKM A;  2W2J A;  2NMX A;  1KOQ A;  1BNM A;  1CAM A;  1URT A;  1MUA A;  3CZV A;  3DVB A;  3M2N A;  3DAZ A;  3M1Q A;  1LG5 A;  1CIM A;  3EFI A;  2NNO A;  1BNW A;  2FOQ A;  2WD3 A;  1XEG A;  2IT4 A;  1UGB A;  2EZ7 A;  3K2F A;  4PYY A;  2NNS A;  3DCW A;  3MNJ A;  3HS4 A;  3IAI A;  1CVA A;  3IEO A;  3F4X A;  1LUG A;  1BIC A;  1HEA A;  3JXH C;  2POV A;  1CCT A;  1TEU X;  2HFX A;  1G48 A;  1JD0 A;  2HNC A;  1ZSB A;  3R16 A;  3MNH A;  1HEB A;  3F8E A;  2OSF A;  1TG9 A;  1CVC A;  1AZM A;  1G45 A;  2NNV A;  2POU A;  2CA2 A;  3OKU A;  1LG6 A;  3IBL A;  3DD8 A;  2HOC A;  3DC9 A;  3IBN A;  2HFW A;  1ZSA A;  1AM6 A;  3M96 A;  3PO6 A;  3KWA A;  1CNC A;  1CRA A;  1KOP A;  1XEV A;  1JV0 A;  3DBU A;  3P4V A;  1RAY A;  2ABE A;  3OIK A;  2H15 A;  1FR4 A;  1I9O A;  3M40 A;  1CAJ A;  2X7S A;  1XPZ A;  3N0N A;  3DA2 A;  1YO0 A;  2CBD A;  3BL1 A;  3HKU A;  2HKK A;  2CAB A;  2FOU A;  3C7P A;  3HLJ A;  1AVN A;  1CAL A;  1BNN A;  1FSR A;  1LGD A;  3D8W A;  3M98 A;  1IF6 A;  1UGA A;  3MDZ A;  1HUH A;  2X7T A;  1FR7 A;  2EU2 A;  3M2Y A;  2VVB X;  2GD8 A;  1KWQ A;  1CZM A;  3JXG A;  3KOK A;  3M1J A;  1CCU A;  1G1D A;  1CNW A;  1THK A;  1UGD A;  1DMY A;  2WEG A;  3JXF A;  1V9I C;  2HD6 A;  1YDB A;  2FNM A;  1TH9 A;  2NWO A;  2OSM A;  3MMF A;  3GZ0 A;  1UGE A;  2CBA A;  1CVB A;  3HKN A;  1A42 A;  1CNX A;  3DC3 A;  1CVF A;  9CA2 A;  1G46 A;  1YDA A;  3K34 A;  3HKT A;  1CRM A;  1H9Q A;  1CA2 A;  1IF9 A;  3N4B A;  3MZC A;  1BNT A;  3MNA A;  1FLJ A;  1G0E A;  3N3J A;  1FQL A;  3B1B A;  1CNJ A;  1HCB A;  1HEC A;  1DCB A;  1I9L A;  3ML2 A;  1CA3 A;  2ZNC A;  3KIG A;  1I8Z A;  2WEJ A;  3HKQ A;  5CA2 A;  1BN1 A;  1OQ5 A;  2NXS A;  3M5S A;  3M67 A;  3MHO A;  3MYQ A;  1TBT X;  1YDD A;  1CVE A;  3FFP X;  1G0F A;  1BN4 A;  2HFY A;  3K7K A;  3KON A;  1I9N A;  2CBC A;  3CA2 A;  1EOU A;  1G3Z A;  2EU3 A;  1I9M A;  1CAY A; 
#chains in the KnotProt database with same CATH topology
 2NXR A;  2NXT A;  1CCS A;  3MNU A;  1BN3 A;  1HVA A;  3DCC A;  2WEO A;  2FMG A;  1CNG A;  3DV7 A;  3N2P A;  2WEH A;  1IF8 A;  2F14 A;  2NN7 A;  12CA A;  1ZE8 A;  3KKX A;  2NN1 A;  3IQK A;  3HFP A;  1FQN A;  1HED A;  1G4J A;  1CIL A;  1BNV A;  3NI5 A;  1ZNC A;  2HL4 A;  2VVA X;  1HCA A;  1CVH A;  1RJ5 A;  1CNY A;  1T9N A;  3L14 A;  6CA2 A;  3DVC A;  1CVD A;  1J9W A;  3B4F A;  1KEQ A;  1YO2 A;  1IF4 A;  1Y7W A;  2WD2 A;  1CIN A;  1V9E A;  3MNI A;  3M3X A;  3FW3 A;  1TE3 X;  3D92 A;  1RJ6 A;  3DVD A;  2X7U A;  1CAK A;  3PYK A;  1OKN A;  1I9Q A;  1BV3 A;  1TTM A;  3D0N A;  1RZD A;  3DD0 A;  5CAC A;  1IF7 A;  3ML5 A;  2CBE A;  3M5E A;  2FNN A;  7CA2 A;  1CAN A;  2AX2 A;  1KWR A;  2NWZ A;  1Z97 A;  1LZV A;  3R17 B;  3OKV A;  3OIL A;  2NWY A;  1CAI A;  1IF5 A;  3MHL A;  1FSN A;  1CNI A;  3MHC A;  2NNG A;  1UGF A;  1CAH A;  1FQM A;  3FE4 A;  1RZE A;  3MHI A;  1DCA A;  2GEH A;  2Q1B A;  3DCS A;  2Q1Q A;  1HUG A;  3EFT A;  2CBB A;  1RAZ A;  3MNK A;  3IBI A;  3IGP A;  1YDC A;  2NWP A;  1H9N A;  2FNK A;  3OIM A;  3F7U A;  3D93 A;  3F7B A;  1RZA A;  2Q38 A;  1F2W A;  3D9Z A;  4CA2 A;  1CAO A;  3ZNC A;  4CAC A;  1RZC A;  1CAZ A;  3M2Z A;  3MHM A;  3IBU A;  8CA2 A;  1G6V A;  3NJ9 A;  2FOS A;  1BNU A;  2O4Z A;  1G53 A;  2POW A;  1I90 A;  2ILI A;  1TG3 A;  3M5T A;  3M1W A;  3BL0 A;  1I91 A;  1XQ0 A;  1FQR A;  3BET A;  1ZSC A;  2FW4 A;  1G4O A;  1YO1 A;  3MWO A;  2FMZ A;  1RZB A;  3LXE A;  1BZM A;  1BCD A;  1CNH A;  1FSQ A;  1H4N A;  1Z93 A;  1BNQ A;  3KS3 A;  3CAJ A;  1I9P A;  2AW1 A;  1G52 A;  1OKM A;  2W2J A;  2NMX A;  1KOQ A;  1BNM A;  1CAM A;  1URT A;  1MUA A;  3CZV A;  3DVB A;  3M2N A;  3DAZ A;  3M1Q A;  1LG5 A;  1CIM A;  3EFI A;  2NNO A;  1BNW A;  2FOQ A;  2WD3 A;  1XEG A;  2IT4 A;  1UGB A;  2EZ7 A;  3K2F A;  4PYY A;  2NNS A;  3DCW A;  3MNJ A;  3HS4 A;  3IAI A;  1CVA A;  3IEO A;  3F4X A;  1LUG A;  1BIC A;  1HEA A;  3JXH C;  2POV A;  1CCT A;  1TEU X;  2HFX A;  1G48 A;  1JD0 A;  2HNC A;  1ZSB A;  3R16 A;  3MNH A;  1HEB A;  3F8E A;  2OSF A;  1TG9 A;  1CVC A;  1AZM A;  1G45 A;  2NNV A;  2POU A;  2CA2 A;  3OKU A;  1LG6 A;  3IBL A;  3DD8 A;  2HOC A;  3DC9 A;  3IBN A;  2HFW A;  1ZSA A;  1AM6 A;  3M96 A;  3PO6 A;  3KWA A;  1CNC A;  1CRA A;  1KOP A;  1XEV A;  1JV0 A;  3DBU A;  3P4V A;  1RAY A;  2ABE A;  3OIK A;  2H15 A;  1FR4 A;  1I9O A;  3M40 A;  1CAJ A;  2X7S A;  1XPZ A;  3N0N A;  3DA2 A;  1YO0 A;  2CBD A;  3BL1 A;  3HKU A;  2HKK A;  2CAB A;  2FOU A;  3C7P A;  3HLJ A;  1AVN A;  1CAL A;  1BNN A;  1FSR A;  1LGD A;  3D8W A;  3M98 A;  1IF6 A;  1UGA A;  3MDZ A;  1HUH A;  2X7T A;  1FR7 A;  2EU2 A;  3M2Y A;  2VVB X;  2GD8 A;  1KWQ A;  1CZM A;  3JXG A;  3KOK A;  3M1J A;  1CCU A;  1G1D A;  1CNW A;  1THK A;  1UGD A;  1DMY A;  2WEG A;  3JXF A;  1V9I C;  2HD6 A;  1YDB A;  2FNM A;  1TH9 A;  2NWO A;  2OSM A;  3MMF A;  3GZ0 A;  1UGE A;  2CBA A;  1CVB A;  3HKN A;  1A42 A;  1CNX A;  3DC3 A;  1CVF A;  9CA2 A;  1G46 A;  1YDA A;  3K34 A;  3HKT A;  1CRM A;  1H9Q A;  1CA2 A;  1IF9 A;  3N4B A;  3MZC A;  1BNT A;  3MNA A;  1FLJ A;  1G0E A;  3N3J A;  1FQL A;  3B1B A;  1CNJ A;  1HCB A;  1HEC A;  1DCB A;  1I9L A;  3ML2 A;  1CA3 A;  2ZNC A;  3KIG A;  1I8Z A;  2WEJ A;  3HKQ A;  5CA2 A;  1BN1 A;  1OQ5 A;  2NXS A;  3M5S A;  3M67 A;  3MHO A;  3MYQ A;  1TBT X;  1YDD A;  1CVE A;  3FFP X;  1G0F A;  1BN4 A;  2HFY A;  3K7K A;  3KON A;  1I9N A;  2CBC A;  3CA2 A;  1EOU A;  1G3Z A;  2EU3 A;  1I9M A;  1CAY A; 
#chains in the KnotProt database with same CATH homology
 2NXR A;  2NXT A;  1CCS A;  3MNU A;  1BN3 A;  1HVA A;  3DCC A;  2WEO A;  2FMG A;  1CNG A;  3DV7 A;  3N2P A;  2WEH A;  1IF8 A;  2F14 A;  2NN7 A;  12CA A;  1ZE8 A;  3KKX A;  2NN1 A;  3IQK A;  3HFP A;  1FQN A;  1HED A;  1G4J A;  1CIL A;  1BNV A;  3NI5 A;  1ZNC A;  2HL4 A;  2VVA X;  1HCA A;  1CVH A;  1RJ5 A;  1CNY A;  1T9N A;  3L14 A;  6CA2 A;  3DVC A;  1CVD A;  1J9W A;  3B4F A;  1KEQ A;  1YO2 A;  1IF4 A;  1Y7W A;  2WD2 A;  1CIN A;  1V9E A;  3MNI A;  3M3X A;  3FW3 A;  1TE3 X;  3D92 A;  1RJ6 A;  3DVD A;  2X7U A;  1CAK A;  3PYK A;  1OKN A;  1I9Q A;  1BV3 A;  1TTM A;  3D0N A;  1RZD A;  3DD0 A;  5CAC A;  1IF7 A;  3ML5 A;  2CBE A;  3M5E A;  2FNN A;  7CA2 A;  1CAN A;  2AX2 A;  1KWR A;  2NWZ A;  1Z97 A;  1LZV A;  3R17 B;  3OKV A;  3OIL A;  2NWY A;  1CAI A;  1IF5 A;  3MHL A;  1FSN A;  1CNI A;  3MHC A;  2NNG A;  1UGF A;  1CAH A;  1FQM A;  3FE4 A;  1RZE A;  3MHI A;  1DCA A;  2GEH A;  2Q1B A;  3DCS A;  2Q1Q A;  1HUG A;  3EFT A;  2CBB A;  1RAZ A;  3MNK A;  3IBI A;  3IGP A;  1YDC A;  2NWP A;  1H9N A;  2FNK A;  3OIM A;  3F7U A;  3D93 A;  3F7B A;  1RZA A;  2Q38 A;  1F2W A;  3D9Z A;  4CA2 A;  1CAO A;  3ZNC A;  4CAC A;  1RZC A;  1CAZ A;  3M2Z A;  3MHM A;  3IBU A;  8CA2 A;  1G6V A;  3NJ9 A;  2FOS A;  1BNU A;  2O4Z A;  1G53 A;  2POW A;  1I90 A;  2ILI A;  1TG3 A;  3M5T A;  3M1W A;  3BL0 A;  1I91 A;  1XQ0 A;  1FQR A;  3BET A;  1ZSC A;  2FW4 A;  1G4O A;  1YO1 A;  3MWO A;  2FMZ A;  1RZB A;  3LXE A;  1BZM A;  1BCD A;  1CNH A;  1FSQ A;  1H4N A;  1Z93 A;  1BNQ A;  3KS3 A;  3CAJ A;  1I9P A;  2AW1 A;  1G52 A;  1OKM A;  2W2J A;  2NMX A;  1KOQ A;  1BNM A;  1CAM A;  1URT A;  1MUA A;  3CZV A;  3DVB A;  3M2N A;  3DAZ A;  3M1Q A;  1LG5 A;  1CIM A;  3EFI A;  2NNO A;  1BNW A;  2FOQ A;  2WD3 A;  1XEG A;  2IT4 A;  1UGB A;  2EZ7 A;  3K2F A;  2NNS A;  3DCW A;  3MNJ A;  3HS4 A;  3IAI A;  1CVA A;  3IEO A;  3F4X A;  1LUG A;  1BIC A;  1HEA A;  3JXH C;  2POV A;  1CCT A;  1TEU X;  2HFX A;  1G48 A;  1JD0 A;  2HNC A;  1ZSB A;  3R16 A;  3MNH A;  1HEB A;  3F8E A;  2OSF A;  1TG9 A;  1CVC A;  1AZM A;  1G45 A;  2NNV A;  2POU A;  2CA2 A;  3OKU A;  1LG6 A;  3IBL A;  3DD8 A;  2HOC A;  3DC9 A;  3IBN A;  2HFW A;  1ZSA A;  1AM6 A;  3M96 A;  3PO6 A;  3KWA A;  1CNC A;  1CRA A;  1KOP A;  1XEV A;  1JV0 A;  3DBU A;  3P4V A;  1RAY A;  2ABE A;  3OIK A;  2H15 A;  1FR4 A;  1I9O A;  3M40 A;  1CAJ A;  2X7S A;  1XPZ A;  3N0N A;  3DA2 A;  1YO0 A;  2CBD A;  3BL1 A;  3HKU A;  2HKK A;  2CAB A;  2FOU A;  3C7P A;  3HLJ A;  1AVN A;  1CAL A;  1BNN A;  1FSR A;  1LGD A;  3D8W A;  3M98 A;  1IF6 A;  1UGA A;  3MDZ A;  1HUH A;  2X7T A;  1FR7 A;  2EU2 A;  3M2Y A;  2VVB X;  2GD8 A;  1KWQ A;  1CZM A;  3JXG A;  3KOK A;  3M1J A;  1CCU A;  1G1D A;  1CNW A;  1THK A;  1UGD A;  1DMY A;  2WEG A;  3JXF A;  1V9I C;  2HD6 A;  1YDB A;  2FNM A;  1TH9 A;  2NWO A;  2OSM A;  3MMF A;  3GZ0 A;  1UGE A;  2CBA A;  1CVB A;  3HKN A;  1A42 A;  1CNX A;  3DC3 A;  1CVF A;  9CA2 A;  1G46 A;  1YDA A;  3K34 A;  3HKT A;  1CRM A;  1H9Q A;  1CA2 A;  1IF9 A;  3N4B A;  3MZC A;  1BNT A;  3MNA A;  1FLJ A;  1G0E A;  3N3J A;  1FQL A;  3B1B A;  1CNJ A;  1HCB A;  1HEC A;  1DCB A;  1I9L A;  3ML2 A;  1CA3 A;  2ZNC A;  3KIG A;  1I8Z A;  2WEJ A;  3HKQ A;  5CA2 A;  1BN1 A;  1OQ5 A;  2NXS A;  3M5S A;  3M67 A;  3MHO A;  3MYQ A;  1TBT X;  1YDD A;  1CVE A;  3FFP X;  1G0F A;  1BN4 A;  2HFY A;  3K7K A;  3KON A;  1I9N A;  2CBC A;  3CA2 A;  1EOU A;  1G3Z A;  2EU3 A;  1I9M A;  1CAY A;
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similar chains in the KnotProt database (?% sequence similarity)
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#similar chains in the KnotProt database (?% sequence similarity)
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