3L14A

Human carbonic anhydrase ii complexed with althiazide
Genus: 73
Alphaknot: P00918
Slipknot S +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 21-255 235 1-20, 256-258 20 3 knot
Chain Sequence
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 3x +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 24-255 232 1-23, 256-258 23 3 knot
Fingerprint Knot forming loop Loop type
K +31 His4 ... His94 <->
Bridging ionZn262
<-> His96 ...
Chain closureLys261 <-> His4
 probabilistic
K +31 His4 ... His96 <->
Bridging ionZn262
<-> His119 ...
Chain closureLys261 <-> His4
 probabilistic
K +31 His4 ... His94 <->
Bridging ionZn262
<-> His119 ...
Chain closureLys261 <-> His4
 probabilistic
Chain Sequence
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 25-256 232 1-24, 257-257 24 1 knot
view details
2.1 24-251 228 1-23 257-257 252-256 23 1 slipknot
sequence length 257
structure length 257
publication title The Promiscuous Nature of Althiazide in Adducts with CA II and CA IX Mimic
rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
total genus Genus: 73
ec nomenclature ec 4.2.1.1: Carbonate dehydratase.
pdb deposition date 2009-12-10
KnotProt deposition date 2018-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00194 Carb_anhydrase Eukaryotic-type carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 3l14A00
3.10.200.10 Alpha Beta Roll Carbonic Anhydrase II Carbonic Anhydrase II 3l14A00
1H9QA 1UGFA 1CAIA 1TH9A 1G48A 3KS3A 1G0EA 3D93A 1CNGA 1I9QA 1I9PA 1CVBA 1V9IC 2FMGA 1T9NA 3M40A 3KONA 4PYYA 1CALA 1CVDA 12CAA 3CA2A 2HFYA 3IEOA 2X7TA 3DD8A 1CNWA 2WEHA 1CVHA 1BNWA 1G3ZA 1YDBA 1FR4A 3JXFA 1I9OA 3N2PA 1CAYA 3BL0A 1G0FA 1FQMA 2O4ZA 1TTMA 3DBUA 3IGPA 3DC3A 2Q1BA 3F7BA 1KOQA 3MNAA 2HOCA 1CVEA 1YO1A 1ZE8A 3PO6A 3DAZA 3NI5A 2X7SA 2NNVA 2ZNCA 1J9WA 1H4NA 1CAHA 2Q38A 1RZEA 2EU2A 1YDCA 1BNVA 1YO0A 3MHOA 3M1JA 1CIMA 3OIMA 1CNHA 3MHLA 3OKVA 3OKUA 1OKMA 1A42A 2ABEA 1F2WA 3C7PA 1RZCA 2WEOA 1DCBA 1CAKA 3R16A 1JV0A 3B4FA 2FNMA 3DVBA 1FSQA 3LXEA 1CAMA 1FQLA 2CBAA 4CACA 1AZMA 3EFTA 1I90A 1FQRA 2VVAX 1XPZA 3IBNA 1CANA 3EFIA 3M67A 1JD0A 1TG9A 2FMZA 3N0NA 1BN1A 1HUHA 1CILA 2H15A 2NN7A 2NWOA 2OSFA 2Q1QA 3NJ9A 3N3JA 1XEGA 1G45A 3BL1A 3MMFA 3OIKA 3GZ0A 1AM6A 3MHIA 1G1DA 3M5EA 2CBCA 2EU3A 2CBBA 1KEQA 1FSNA 1G6VA 3DCCA 2AW1A 1IF8A 1CAZA 3BETA 1BN4A 1RZBA 3DV7A 1CRAA 2NXSA 1Z93A 1H9NA 2HFWA 2HKKA 1DCAA 3KIGA 3MNJA 1G4JA 3OILA 1CNIA 2HL4A 1ZSBA 3HKTA 1CVAA 1CNCA 1UGBA 1CRMA 3K34A 3M5TA 1IF5A 2FOUA 1HUGA 3M2YA 3MZCA 3M96A 6CA2A 3JXHC 1YDAA 1Z97A 1CVFA 3JXGA 3IBIA 1BNTA 3DCWA 2NWZA 3HKUA 3M1WA 2VVBX 3ZNCA 1IF7A 1RZAA 3MYQA 2IT4A 2OSMA 3M2ZA 2POVA 1CCSA 2WD2A 3IAIA 1FQNA 1EOUA 3D9ZA 3M1QA 2FNKA 2CBEA 1HCAA 2WEGA 2FNNA 3L14A 1I9NA 5CA2A 1CNXA 1CVCA 7CA2A 2HFXA 1FSRA 2FOQA 2ILIA 1UGEA 1I9LA 1IF9A 1ZSCA 3F8EA 1HEBA 3HFPA 1CZMA 2GD8A 1YDDA 3KKXA 3HKQA 1CNYA 1G4OA 2NNOA 2X7UA 1RJ6A 1KOPA 9CA2A 1OQ5A 4CA2A 3DD0A 1I8ZA 1G46A 2F14A 3HLJA 2WD3A 1CA3A 1I91A 1RZDA 1BZMA 2POWA 1YO2A 2NMXA 1CCTA 3CZVA 1Y7WA 2EZ7A 3PYKA 8CA2A 3FFPX 1HCBA 2FOSA 3CAJA 2W2JA 3IBUA 2NN1A 1CA2A 1TEUX 3DC9A 1BNUA 3D92A 1CINA 1BV3A 2NNSA 1UGAA 2WEJA 1BNQA 3MHCA 1IF4A 3M98A 1G52A 1XEVA 3N4BA 2POUA 1CAJA 2FW4A 3DCSA 1LGDA 2AX2A 1G53A 2NXTA 1LZVA 1ZSAA 1UGDA 1I9MA 3KWAA 2NWYA 3F7UA 1TE3X 3MNKA 3ML2A 3K2FA 1HEAA 3ML5A 3DVDA 3P4VA 1RJ5A 3IBLA 1THKA 1OKNA 1LG5A 2GEHA 1RAZA 3HKNA 3M3XA 2CA2A 3DVCA 3MNIA 1BICA 1RAYA 1CAOA 3IQKA 1AVNA 1FR7A 1V9EA 1URTA 5CACA 3MHMA 1CNJA 3FW3A 1KWRA 1DMYA 1BNMA 3HS4A 3MNUA 2HD6A 1TBTX 1MUAA 1ZNCA 3MWOA 3R17B 3MNHA 3B1BA 1BCDA 1TG3A 2NXRA 1CCUA 2NWPA 1HEDA 3D8WA 3F4XA 1KWQA 1LG6A 1LUGA 1HECA 1BNNA 2CABA 3K7KA 3M2NA 3DA2A 1IF6A 3M5SA 1FLJA 3MDZA 2NNGA 1HVAA 2CBDA 3FE4A 3KOKA 1XQ0A 1BN3A 3D0NA 2HNCA
chains in the KnotProt database with same CATH superfamily
1H9QA 1UGFA 1CAIA 1TH9A 1G48A 3KS3A 1G0EA 3D93A 1CNGA 1I9QA 1I9PA 1CVBA 1V9IC 2FMGA 1T9NA 3M40A 3KONA 4PYYA 1CALA 1CVDA 12CAA 3CA2A 2HFYA 3IEOA 2X7TA 3DD8A 1CNWA 2WEHA 1CVHA 1BNWA 1G3ZA 1YDBA 1FR4A 3JXFA 1I9OA 3N2PA 1CAYA 3BL0A 1G0FA 1FQMA 2O4ZA 1TTMA 3DBUA 3IGPA 3DC3A 2Q1BA 3F7BA 1KOQA 3MNAA 2HOCA 1CVEA 1YO1A 1ZE8A 3PO6A 3DAZA 3NI5A 2X7SA 2NNVA 2ZNCA 1J9WA 1H4NA 1CAHA 2Q38A 1RZEA 2EU2A 1YDCA 1BNVA 1YO0A 3MHOA 3M1JA 1CIMA 3OIMA 1CNHA 3MHLA 3OKVA 3OKUA 1OKMA 1A42A 2ABEA 1F2WA 3C7PA 1RZCA 2WEOA 1DCBA 1CAKA 3R16A 1JV0A 3B4FA 2FNMA 3DVBA 1FSQA 3LXEA 1CAMA 1FQLA 2CBAA 4CACA 1AZMA 3EFTA 1I90A 1FQRA 2VVAX 1XPZA 3IBNA 1CANA 3EFIA 3M67A 1JD0A 1TG9A 2FMZA 3N0NA 1BN1A 1HUHA 1CILA 2H15A 2NN7A 2NWOA 2OSFA 2Q1QA 3NJ9A 3N3JA 1XEGA 1G45A 3BL1A 3MMFA 3OIKA 3GZ0A 1AM6A 3MHIA 1G1DA 3M5EA 2CBCA 2EU3A 2CBBA 1KEQA 1FSNA 1G6VA 3DCCA 2AW1A 1IF8A 1CAZA 3BETA 1BN4A 1RZBA 3DV7A 1CRAA 2NXSA 1Z93A 1H9NA 2HFWA 2HKKA 1DCAA 3KIGA 3MNJA 1G4JA 3OILA 1CNIA 2HL4A 1ZSBA 3HKTA 1CVAA 1CNCA 1UGBA 1CRMA 3K34A 3M5TA 1IF5A 2FOUA 1HUGA 3M2YA 3MZCA 3M96A 6CA2A 3JXHC 1YDAA 1Z97A 1CVFA 3JXGA 3IBIA 1BNTA 3DCWA 2NWZA 3HKUA 3M1WA 2VVBX 3ZNCA 1IF7A 1RZAA 3MYQA 2IT4A 2OSMA 3M2ZA 2POVA 1CCSA 2WD2A 3IAIA 1FQNA 1EOUA 3D9ZA 3M1QA 2FNKA 2CBEA 1HCAA 2WEGA 2FNNA 3L14A 1I9NA 5CA2A 1CNXA 1CVCA 7CA2A 2HFXA 1FSRA 2FOQA 2ILIA 1UGEA 1I9LA 1IF9A 1ZSCA 3F8EA 1HEBA 3HFPA 1CZMA 2GD8A 1YDDA 3KKXA 3HKQA 1CNYA 1G4OA 2NNOA 2X7UA 1RJ6A 1KOPA 9CA2A 1OQ5A 4CA2A 3DD0A 1I8ZA 1G46A 2F14A 3HLJA 2WD3A 1CA3A 1I91A 1RZDA 1BZMA 2POWA 1YO2A 2NMXA 1CCTA 3CZVA 1Y7WA 2EZ7A 3PYKA 8CA2A 3FFPX 1HCBA 2FOSA 3CAJA 2W2JA 3IBUA 2NN1A 1CA2A 1TEUX 3DC9A 1BNUA 3D92A 1CINA 1BV3A 2NNSA 1UGAA 2WEJA 1BNQA 3MHCA 1IF4A 3M98A 1G52A 1XEVA 3N4BA 2POUA 1CAJA 2FW4A 3DCSA 1LGDA 2AX2A 1G53A 2NXTA 1LZVA 1ZSAA 1UGDA 1I9MA 3KWAA 2NWYA 3F7UA 1TE3X 3MNKA 3ML2A 3K2FA 1HEAA 3ML5A 3DVDA 3P4VA 1RJ5A 3IBLA 1THKA 1OKNA 1LG5A 2GEHA 1RAZA 3HKNA 3M3XA 2CA2A 3DVCA 3MNIA 1BICA 1RAYA 1CAOA 3IQKA 1AVNA 1FR7A 1V9EA 1URTA 5CACA 3MHMA 1CNJA 3FW3A 1KWRA 1DMYA 1BNMA 3HS4A 3MNUA 2HD6A 1TBTX 1MUAA 1ZNCA 3MWOA 3R17B 3MNHA 3B1BA 1BCDA 1TG3A 2NXRA 1CCUA 2NWPA 1HEDA 3D8WA 3F4XA 1KWQA 1LG6A 1LUGA 1HECA 1BNNA 2CABA 3K7KA 3M2NA 3DA2A 1IF6A 3M5SA 1FLJA 3MDZA 2NNGA 1HVAA 2CBDA 3FE4A 3KOKA 1XQ0A 1BN3A 3D0NA 2HNCA
chains in the KnotProt database with same CATH topology
1H9QA 1UGFA 1CAIA 1TH9A 1G48A 3KS3A 1G0EA 3D93A 1CNGA 1I9QA 1I9PA 1CVBA 1V9IC 2FMGA 1T9NA 3M40A 3KONA 1CALA 1CVDA 12CAA 3CA2A 2HFYA 3IEOA 2X7TA 3DD8A 1CNWA 2WEHA 1CVHA 1BNWA 1G3ZA 1YDBA 1FR4A 3JXFA 1I9OA 3N2PA 1CAYA 3BL0A 1G0FA 1FQMA 2O4ZA 1TTMA 3DBUA 3IGPA 3DC3A 2Q1BA 3F7BA 1KOQA 3MNAA 2HOCA 1CVEA 1YO1A 1ZE8A 3PO6A 3DAZA 3NI5A 2X7SA 2NNVA 2ZNCA 1J9WA 1H4NA 1CAHA 2Q38A 1RZEA 2EU2A 1YDCA 1BNVA 1YO0A 3MHOA 3M1JA 1CIMA 3OIMA 1CNHA 3MHLA 3OKVA 3OKUA 1OKMA 1A42A 2ABEA 1F2WA 3C7PA 1RZCA 2WEOA 1DCBA 1CAKA 3R16A 1JV0A 3B4FA 2FNMA 3DVBA 1FSQA 3LXEA 1CAMA 1FQLA 2CBAA 4CACA 1AZMA 3EFTA 1I90A 1FQRA 2VVAX 1XPZA 3IBNA 1CANA 3EFIA 3M67A 1JD0A 1TG9A 2FMZA 3N0NA 1BN1A 1HUHA 1CILA 2H15A 2NN7A 2NWOA 2OSFA 2Q1QA 3NJ9A 3N3JA 1XEGA 1G45A 3BL1A 3MMFA 3OIKA 3GZ0A 1AM6A 3MHIA 1G1DA 3M5EA 2CBCA 2EU3A 2CBBA 1KEQA 1FSNA 1G6VA 3DCCA 2AW1A 1IF8A 1CAZA 3BETA 1BN4A 1RZBA 3DV7A 1CRAA 2NXSA 1Z93A 1H9NA 2HFWA 2HKKA 1DCAA 3KIGA 3MNJA 1G4JA 3OILA 1CNIA 2HL4A 1ZSBA 3HKTA 1CVAA 1CNCA 1UGBA 1CRMA 3K34A 3M5TA 1IF5A 2FOUA 1HUGA 3M2YA 3MZCA 3M96A 6CA2A 3JXHC 1YDAA 1Z97A 1CVFA 3JXGA 3IBIA 1BNTA 3DCWA 2NWZA 3HKUA 3M1WA 2VVBX 3ZNCA 1IF7A 1RZAA 3MYQA 2IT4A 2OSMA 3M2ZA 2POVA 1CCSA 2WD2A 3IAIA 1FQNA 1EOUA 3D9ZA 3M1QA 2FNKA 2CBEA 1HCAA 2WEGA 2FNNA 3L14A 1I9NA 5CA2A 1CNXA 1CVCA 7CA2A 2HFXA 1FSRA 2FOQA 2ILIA 1UGEA 1I9LA 1IF9A 1ZSCA 3F8EA 1HEBA 3HFPA 1CZMA 2GD8A 1YDDA 3KKXA 3HKQA 1CNYA 1G4OA 2NNOA 2X7UA 1RJ6A 1KOPA 9CA2A 1OQ5A 4CA2A 3DD0A 1I8ZA 1G46A 2F14A 3HLJA 2WD3A 1CA3A 1I91A 1RZDA 1BZMA 2POWA 1YO2A 2NMXA 1CCTA 3CZVA 1Y7WA 2EZ7A 3PYKA 8CA2A 3FFPX 1HCBA 2FOSA 3CAJA 2W2JA 3IBUA 2NN1A 1CA2A 1TEUX 3DC9A 1BNUA 3D92A 1CINA 1BV3A 2NNSA 1UGAA 2WEJA 1BNQA 3MHCA 1IF4A 3M98A 1G52A 1XEVA 3N4BA 2POUA 1CAJA 2FW4A 3DCSA 1LGDA 2AX2A 1G53A 2NXTA 1LZVA 1ZSAA 1UGDA 1I9MA 3KWAA 2NWYA 3F7UA 1TE3X 3MNKA 3ML2A 3K2FA 1HEAA 3ML5A 3DVDA 3P4VA 1RJ5A 3IBLA 1THKA 1OKNA 1LG5A 2GEHA 1RAZA 3HKNA 3M3XA 2CA2A 3DVCA 3MNIA 1BICA 1RAYA 1CAOA 3IQKA 1AVNA 1FR7A 1V9EA 1URTA 5CACA 3MHMA 1CNJA 3FW3A 1KWRA 1DMYA 1BNMA 3HS4A 3MNUA 2HD6A 1TBTX 1MUAA 1ZNCA 3MWOA 3R17B 3MNHA 3B1BA 1BCDA 1TG3A 2NXRA 1CCUA 2NWPA 1HEDA 3D8WA 3F4XA 1KWQA 1LG6A 1LUGA 1HECA 1BNNA 2CABA 3K7KA 3M2NA 3DA2A 1IF6A 3M5SA 1FLJA 3MDZA 2NNGA 1HVAA 2CBDA 3FE4A 3KOKA 1XQ0A 1BN3A 3D0NA 2HNCA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 1H9Q A;  1UGF A;  1CAI A;  1TH9 A;  1G48 A;  3KS3 A;  1G0E A;  3D93 A;  1CNG A;  1I9Q A;  1I9P A;  1CVB A;  1V9I C;  2FMG A;  1T9N A;  3M40 A;  3KON A;  4PYY A;  1CAL A;  1CVD A;  12CA A;  3CA2 A;  2HFY A;  3IEO A;  2X7T A;  3DD8 A;  1CNW A;  2WEH A;  1CVH A;  1BNW A;  1G3Z A;  1YDB A;  1FR4 A;  3JXF A;  1I9O A;  3N2P A;  1CAY A;  3BL0 A;  1G0F A;  1FQM A;  2O4Z A;  1TTM A;  3DBU A;  3IGP A;  3DC3 A;  2Q1B A;  3F7B A;  1KOQ A;  3MNA A;  2HOC A;  1CVE A;  1YO1 A;  1ZE8 A;  3PO6 A;  3DAZ A;  3NI5 A;  2X7S A;  2NNV A;  2ZNC A;  1J9W A;  1H4N A;  1CAH A;  2Q38 A;  1RZE A;  2EU2 A;  1YDC A;  1BNV A;  1YO0 A;  3MHO A;  3M1J A;  1CIM A;  3OIM A;  1CNH A;  3MHL A;  3OKV A;  3OKU A;  1OKM A;  1A42 A;  2ABE A;  1F2W A;  3C7P A;  1RZC A;  2WEO A;  1DCB A;  1CAK A;  3R16 A;  1JV0 A;  3B4F A;  2FNM A;  3DVB A;  1FSQ A;  3LXE A;  1CAM A;  1FQL A;  2CBA A;  4CAC A;  1AZM A;  3EFT A;  1I90 A;  1FQR A;  2VVA X;  1XPZ A;  3IBN A;  1CAN A;  3EFI A;  3M67 A;  1JD0 A;  1TG9 A;  2FMZ A;  3N0N A;  1BN1 A;  1HUH A;  1CIL A;  2H15 A;  2NN7 A;  2NWO A;  2OSF A;  2Q1Q A;  3NJ9 A;  3N3J A;  1XEG A;  1G45 A;  3BL1 A;  3MMF A;  3OIK A;  3GZ0 A;  1AM6 A;  3MHI A;  1G1D A;  3M5E A;  2CBC A;  2EU3 A;  2CBB A;  1KEQ A;  1FSN A;  1G6V A;  3DCC A;  2AW1 A;  1IF8 A;  1CAZ A;  3BET A;  1BN4 A;  1RZB A;  3DV7 A;  1CRA A;  2NXS A;  1Z93 A;  1H9N A;  2HFW A;  2HKK A;  1DCA A;  3KIG A;  3MNJ A;  1G4J A;  3OIL A;  1CNI A;  2HL4 A;  1ZSB A;  3HKT A;  1CVA A;  1CNC A;  1UGB A;  1CRM A;  3K34 A;  3M5T A;  1IF5 A;  2FOU A;  1HUG A;  3M2Y A;  3MZC A;  3M96 A;  6CA2 A;  3JXH C;  1YDA A;  1Z97 A;  1CVF A;  3JXG A;  3IBI A;  1BNT A;  3DCW A;  2NWZ A;  3HKU A;  3M1W A;  2VVB X;  3ZNC A;  1IF7 A;  1RZA A;  3MYQ A;  2IT4 A;  2OSM A;  3M2Z A;  2POV A;  1CCS A;  2WD2 A;  3IAI A;  1FQN A;  1EOU A;  3D9Z A;  3M1Q A;  2FNK A;  2CBE A;  1HCA A;  2WEG A;  2FNN A;  3L14 A;  1I9N A;  5CA2 A;  1CNX A;  1CVC A;  7CA2 A;  2HFX A;  1FSR A;  2FOQ A;  2ILI A;  1UGE A;  1I9L A;  1IF9 A;  1ZSC A;  3F8E A;  1HEB A;  3HFP A;  1CZM A;  2GD8 A;  1YDD A;  3KKX A;  3HKQ A;  1CNY A;  1G4O A;  2NNO A;  2X7U A;  1RJ6 A;  1KOP A;  9CA2 A;  1OQ5 A;  4CA2 A;  3DD0 A;  1I8Z A;  1G46 A;  2F14 A;  3HLJ A;  2WD3 A;  1CA3 A;  1I91 A;  1RZD A;  1BZM A;  2POW A;  1YO2 A;  2NMX A;  1CCT A;  3CZV A;  1Y7W A;  2EZ7 A;  3PYK A;  8CA2 A;  3FFP X;  1HCB A;  2FOS A;  3CAJ A;  2W2J A;  3IBU A;  2NN1 A;  1CA2 A;  1TEU X;  3DC9 A;  1BNU A;  3D92 A;  1CIN A;  1BV3 A;  2NNS A;  1UGA A;  2WEJ A;  1BNQ A;  3MHC A;  1IF4 A;  3M98 A;  1G52 A;  1XEV A;  3N4B A;  2POU A;  1CAJ A;  2FW4 A;  3DCS A;  1LGD A;  2AX2 A;  1G53 A;  2NXT A;  1LZV A;  1ZSA A;  1UGD A;  1I9M A;  3KWA A;  2NWY A;  3F7U A;  1TE3 X;  3MNK A;  3ML2 A;  3K2F A;  1HEA A;  3ML5 A;  3DVD A;  3P4V A;  1RJ5 A;  3IBL A;  1THK A;  1OKN A;  1LG5 A;  2GEH A;  1RAZ A;  3HKN A;  3M3X A;  2CA2 A;  3DVC A;  3MNI A;  1BIC A;  1RAY A;  1CAO A;  3IQK A;  1AVN A;  1FR7 A;  1V9E A;  1URT A;  5CAC A;  3MHM A;  1CNJ A;  3FW3 A;  1KWR A;  1DMY A;  1BNM A;  3HS4 A;  3MNU A;  2HD6 A;  1TBT X;  1MUA A;  1ZNC A;  3MWO A;  3R17 B;  3MNH A;  3B1B A;  1BCD A;  1TG3 A;  2NXR A;  1CCU A;  2NWP A;  1HED A;  3D8W A;  3F4X A;  1KWQ A;  1LG6 A;  1LUG A;  1HEC A;  1BNN A;  2CAB A;  3K7K A;  3M2N A;  3DA2 A;  1IF6 A;  3M5S A;  1FLJ A;  3MDZ A;  2NNG A;  1HVA A;  2CBD A;  3FE4 A;  3KOK A;  1XQ0 A;  1BN3 A;  3D0N A;  2HNC A; 
#chains in the KnotProt database with same CATH topology
 1H9Q A;  1UGF A;  1CAI A;  1TH9 A;  1G48 A;  3KS3 A;  1G0E A;  3D93 A;  1CNG A;  1I9Q A;  1I9P A;  1CVB A;  1V9I C;  2FMG A;  1T9N A;  3M40 A;  3KON A;  4PYY A;  1CAL A;  1CVD A;  12CA A;  3CA2 A;  2HFY A;  3IEO A;  2X7T A;  3DD8 A;  1CNW A;  2WEH A;  1CVH A;  1BNW A;  1G3Z A;  1YDB A;  1FR4 A;  3JXF A;  1I9O A;  3N2P A;  1CAY A;  3BL0 A;  1G0F A;  1FQM A;  2O4Z A;  1TTM A;  3DBU A;  3IGP A;  3DC3 A;  2Q1B A;  3F7B A;  1KOQ A;  3MNA A;  2HOC A;  1CVE A;  1YO1 A;  1ZE8 A;  3PO6 A;  3DAZ A;  3NI5 A;  2X7S A;  2NNV A;  2ZNC A;  1J9W A;  1H4N A;  1CAH A;  2Q38 A;  1RZE A;  2EU2 A;  1YDC A;  1BNV A;  1YO0 A;  3MHO A;  3M1J A;  1CIM A;  3OIM A;  1CNH A;  3MHL A;  3OKV A;  3OKU A;  1OKM A;  1A42 A;  2ABE A;  1F2W A;  3C7P A;  1RZC A;  2WEO A;  1DCB A;  1CAK A;  3R16 A;  1JV0 A;  3B4F A;  2FNM A;  3DVB A;  1FSQ A;  3LXE A;  1CAM A;  1FQL A;  2CBA A;  4CAC A;  1AZM A;  3EFT A;  1I90 A;  1FQR A;  2VVA X;  1XPZ A;  3IBN A;  1CAN A;  3EFI A;  3M67 A;  1JD0 A;  1TG9 A;  2FMZ A;  3N0N A;  1BN1 A;  1HUH A;  1CIL A;  2H15 A;  2NN7 A;  2NWO A;  2OSF A;  2Q1Q A;  3NJ9 A;  3N3J A;  1XEG A;  1G45 A;  3BL1 A;  3MMF A;  3OIK A;  3GZ0 A;  1AM6 A;  3MHI A;  1G1D A;  3M5E A;  2CBC A;  2EU3 A;  2CBB A;  1KEQ A;  1FSN A;  1G6V A;  3DCC A;  2AW1 A;  1IF8 A;  1CAZ A;  3BET A;  1BN4 A;  1RZB A;  3DV7 A;  1CRA A;  2NXS A;  1Z93 A;  1H9N A;  2HFW A;  2HKK A;  1DCA A;  3KIG A;  3MNJ A;  1G4J A;  3OIL A;  1CNI A;  2HL4 A;  1ZSB A;  3HKT A;  1CVA A;  1CNC A;  1UGB A;  1CRM A;  3K34 A;  3M5T A;  1IF5 A;  2FOU A;  1HUG A;  3M2Y A;  3MZC A;  3M96 A;  6CA2 A;  3JXH C;  1YDA A;  1Z97 A;  1CVF A;  3JXG A;  3IBI A;  1BNT A;  3DCW A;  2NWZ A;  3HKU A;  3M1W A;  2VVB X;  3ZNC A;  1IF7 A;  1RZA A;  3MYQ A;  2IT4 A;  2OSM A;  3M2Z A;  2POV A;  1CCS A;  2WD2 A;  3IAI A;  1FQN A;  1EOU A;  3D9Z A;  3M1Q A;  2FNK A;  2CBE A;  1HCA A;  2WEG A;  2FNN A;  3L14 A;  1I9N A;  5CA2 A;  1CNX A;  1CVC A;  7CA2 A;  2HFX A;  1FSR A;  2FOQ A;  2ILI A;  1UGE A;  1I9L A;  1IF9 A;  1ZSC A;  3F8E A;  1HEB A;  3HFP A;  1CZM A;  2GD8 A;  1YDD A;  3KKX A;  3HKQ A;  1CNY A;  1G4O A;  2NNO A;  2X7U A;  1RJ6 A;  1KOP A;  9CA2 A;  1OQ5 A;  4CA2 A;  3DD0 A;  1I8Z A;  1G46 A;  2F14 A;  3HLJ A;  2WD3 A;  1CA3 A;  1I91 A;  1RZD A;  1BZM A;  2POW A;  1YO2 A;  2NMX A;  1CCT A;  3CZV A;  1Y7W A;  2EZ7 A;  3PYK A;  8CA2 A;  3FFP X;  1HCB A;  2FOS A;  3CAJ A;  2W2J A;  3IBU A;  2NN1 A;  1CA2 A;  1TEU X;  3DC9 A;  1BNU A;  3D92 A;  1CIN A;  1BV3 A;  2NNS A;  1UGA A;  2WEJ A;  1BNQ A;  3MHC A;  1IF4 A;  3M98 A;  1G52 A;  1XEV A;  3N4B A;  2POU A;  1CAJ A;  2FW4 A;  3DCS A;  1LGD A;  2AX2 A;  1G53 A;  2NXT A;  1LZV A;  1ZSA A;  1UGD A;  1I9M A;  3KWA A;  2NWY A;  3F7U A;  1TE3 X;  3MNK A;  3ML2 A;  3K2F A;  1HEA A;  3ML5 A;  3DVD A;  3P4V A;  1RJ5 A;  3IBL A;  1THK A;  1OKN A;  1LG5 A;  2GEH A;  1RAZ A;  3HKN A;  3M3X A;  2CA2 A;  3DVC A;  3MNI A;  1BIC A;  1RAY A;  1CAO A;  3IQK A;  1AVN A;  1FR7 A;  1V9E A;  1URT A;  5CAC A;  3MHM A;  1CNJ A;  3FW3 A;  1KWR A;  1DMY A;  1BNM A;  3HS4 A;  3MNU A;  2HD6 A;  1TBT X;  1MUA A;  1ZNC A;  3MWO A;  3R17 B;  3MNH A;  3B1B A;  1BCD A;  1TG3 A;  2NXR A;  1CCU A;  2NWP A;  1HED A;  3D8W A;  3F4X A;  1KWQ A;  1LG6 A;  1LUG A;  1HEC A;  1BNN A;  2CAB A;  3K7K A;  3M2N A;  3DA2 A;  1IF6 A;  3M5S A;  1FLJ A;  3MDZ A;  2NNG A;  1HVA A;  2CBD A;  3FE4 A;  3KOK A;  1XQ0 A;  1BN3 A;  3D0N A;  2HNC A; 
#chains in the KnotProt database with same CATH homology
 1H9Q A;  1UGF A;  1CAI A;  1TH9 A;  1G48 A;  3KS3 A;  1G0E A;  3D93 A;  1CNG A;  1I9Q A;  1I9P A;  1CVB A;  1V9I C;  2FMG A;  1T9N A;  3M40 A;  3KON A;  1CAL A;  1CVD A;  12CA A;  3CA2 A;  2HFY A;  3IEO A;  2X7T A;  3DD8 A;  1CNW A;  2WEH A;  1CVH A;  1BNW A;  1G3Z A;  1YDB A;  1FR4 A;  3JXF A;  1I9O A;  3N2P A;  1CAY A;  3BL0 A;  1G0F A;  1FQM A;  2O4Z A;  1TTM A;  3DBU A;  3IGP A;  3DC3 A;  2Q1B A;  3F7B A;  1KOQ A;  3MNA A;  2HOC A;  1CVE A;  1YO1 A;  1ZE8 A;  3PO6 A;  3DAZ A;  3NI5 A;  2X7S A;  2NNV A;  2ZNC A;  1J9W A;  1H4N A;  1CAH A;  2Q38 A;  1RZE A;  2EU2 A;  1YDC A;  1BNV A;  1YO0 A;  3MHO A;  3M1J A;  1CIM A;  3OIM A;  1CNH A;  3MHL A;  3OKV A;  3OKU A;  1OKM A;  1A42 A;  2ABE A;  1F2W A;  3C7P A;  1RZC A;  2WEO A;  1DCB A;  1CAK A;  3R16 A;  1JV0 A;  3B4F A;  2FNM A;  3DVB A;  1FSQ A;  3LXE A;  1CAM A;  1FQL A;  2CBA A;  4CAC A;  1AZM A;  3EFT A;  1I90 A;  1FQR A;  2VVA X;  1XPZ A;  3IBN A;  1CAN A;  3EFI A;  3M67 A;  1JD0 A;  1TG9 A;  2FMZ A;  3N0N A;  1BN1 A;  1HUH A;  1CIL A;  2H15 A;  2NN7 A;  2NWO A;  2OSF A;  2Q1Q A;  3NJ9 A;  3N3J A;  1XEG A;  1G45 A;  3BL1 A;  3MMF A;  3OIK A;  3GZ0 A;  1AM6 A;  3MHI A;  1G1D A;  3M5E A;  2CBC A;  2EU3 A;  2CBB A;  1KEQ A;  1FSN A;  1G6V A;  3DCC A;  2AW1 A;  1IF8 A;  1CAZ A;  3BET A;  1BN4 A;  1RZB A;  3DV7 A;  1CRA A;  2NXS A;  1Z93 A;  1H9N A;  2HFW A;  2HKK A;  1DCA A;  3KIG A;  3MNJ A;  1G4J A;  3OIL A;  1CNI A;  2HL4 A;  1ZSB A;  3HKT A;  1CVA A;  1CNC A;  1UGB A;  1CRM A;  3K34 A;  3M5T A;  1IF5 A;  2FOU A;  1HUG A;  3M2Y A;  3MZC A;  3M96 A;  6CA2 A;  3JXH C;  1YDA A;  1Z97 A;  1CVF A;  3JXG A;  3IBI A;  1BNT A;  3DCW A;  2NWZ A;  3HKU A;  3M1W A;  2VVB X;  3ZNC A;  1IF7 A;  1RZA A;  3MYQ A;  2IT4 A;  2OSM A;  3M2Z A;  2POV A;  1CCS A;  2WD2 A;  3IAI A;  1FQN A;  1EOU A;  3D9Z A;  3M1Q A;  2FNK A;  2CBE A;  1HCA A;  2WEG A;  2FNN A;  3L14 A;  1I9N A;  5CA2 A;  1CNX A;  1CVC A;  7CA2 A;  2HFX A;  1FSR A;  2FOQ A;  2ILI A;  1UGE A;  1I9L A;  1IF9 A;  1ZSC A;  3F8E A;  1HEB A;  3HFP A;  1CZM A;  2GD8 A;  1YDD A;  3KKX A;  3HKQ A;  1CNY A;  1G4O A;  2NNO A;  2X7U A;  1RJ6 A;  1KOP A;  9CA2 A;  1OQ5 A;  4CA2 A;  3DD0 A;  1I8Z A;  1G46 A;  2F14 A;  3HLJ A;  2WD3 A;  1CA3 A;  1I91 A;  1RZD A;  1BZM A;  2POW A;  1YO2 A;  2NMX A;  1CCT A;  3CZV A;  1Y7W A;  2EZ7 A;  3PYK A;  8CA2 A;  3FFP X;  1HCB A;  2FOS A;  3CAJ A;  2W2J A;  3IBU A;  2NN1 A;  1CA2 A;  1TEU X;  3DC9 A;  1BNU A;  3D92 A;  1CIN A;  1BV3 A;  2NNS A;  1UGA A;  2WEJ A;  1BNQ A;  3MHC A;  1IF4 A;  3M98 A;  1G52 A;  1XEV A;  3N4B A;  2POU A;  1CAJ A;  2FW4 A;  3DCS A;  1LGD A;  2AX2 A;  1G53 A;  2NXT A;  1LZV A;  1ZSA A;  1UGD A;  1I9M A;  3KWA A;  2NWY A;  3F7U A;  1TE3 X;  3MNK A;  3ML2 A;  3K2F A;  1HEA A;  3ML5 A;  3DVD A;  3P4V A;  1RJ5 A;  3IBL A;  1THK A;  1OKN A;  1LG5 A;  2GEH A;  1RAZ A;  3HKN A;  3M3X A;  2CA2 A;  3DVC A;  3MNI A;  1BIC A;  1RAY A;  1CAO A;  3IQK A;  1AVN A;  1FR7 A;  1V9E A;  1URT A;  5CAC A;  3MHM A;  1CNJ A;  3FW3 A;  1KWR A;  1DMY A;  1BNM A;  3HS4 A;  3MNU A;  2HD6 A;  1TBT X;  1MUA A;  1ZNC A;  3MWO A;  3R17 B;  3MNH A;  3B1B A;  1BCD A;  1TG3 A;  2NXR A;  1CCU A;  2NWP A;  1HED A;  3D8W A;  3F4X A;  1KWQ A;  1LG6 A;  1LUG A;  1HEC A;  1BNN A;  2CAB A;  3K7K A;  3M2N A;  3DA2 A;  1IF6 A;  3M5S A;  1FLJ A;  3MDZ A;  2NNG A;  1HVA A;  2CBD A;  3FE4 A;  3KOK A;  1XQ0 A;  1BN3 A;  3D0N A;  2HNC A;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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