2CX8 | KnotProt

Genus: 70

Knot K +3₁

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Help Knotting data interpretation Full screen

					Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details				+3₁	154-198	45	1-153, 199-225			153	27	knot

Chain Sequence

HRAFSPGLTGVLPLRETRHLVEVLRARVGDRFTVFDGEREALAEVVDLGPPLRYRVLEERRPEREVGVEVVLYVALLKGDKLAEVVRAATELGATRIQPLVTRHSVPKEMGEGKLRRLRAVALEAAKQSGRVVVPEVLPPIPLKAVPQVAQGLVAHVGATARVREVLDPEKPLALAVGPEGGFAEEEVALLEARGFTPVSLGRRILRAETAALALLALCTAGEGR

Whole chain analysis

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Subchain analysis

Knotoid cutoff: 0.5

Knotoid matrix content: 1

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os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

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Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

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Jmol getValue IMAGECallback null

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Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

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Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

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Viewer cachePut cache://localLOAD_/static/knot_data/2cx8/A/2cx8_A.pdb.gz

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Help Knotoid subchains data interpretation Full screen

					Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details				3.1	153-199	47	1-152, 200-225			152	26	knot
view details				2.1	150-196	47	1-149	203-225	197-202	149	23	slipknot

sequence length	225
structure length	225
publication title	Crystal structure of methyltransferase with ligand(SAH) rcsb
molecule tags	Transferase
molecule keywords	methyl transferase
source organism	Thermus thermophilus
total genus	Genus: 70
ec nomenclature
pdb deposition date	2005-06-28
KnotProt deposition date	2014-07-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF04452	Methyltrans_RNA	RNA methyltransferase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.240.20	Mainly Beta	Beta Barrel	Ribosomal Protein L25; Chain P	Hypothetical PUA domain-like; domain 1	2cx8A01
3.40.1280.10	Alpha Beta	3-Layer(aba) Sandwich	Alpha/beta knot	Alpha/beta knot	2cx8A02

3NK7A 3KTYA 3AIAA 1VHYA 2I6DA 3DCMX 3N4JA 3ILKA 4IG6A 3ONPA 1X7OA 1UAJA 3N4KA 3AXZA 3L8UA 2QWVA 3KW2A 4E8BA 2CX8A 3E5YA 1NXZA 1ZJRA 1TO0A 4H3YA 1VHKA 1VH0A 1V6ZA 4FAKA 2Z0YA 1GZ0A 4CNGB 3QUVA 1K3RA 3NK6A 1UAKA 1UALA 3AI9X 3GYQA 3IC6A 4H3ZA 2QMMA 4CNFB 1NS5A 1V2XA 2HA8A 2YY8A 1O6DA 3IEFA 1X7PA 3KY7A 2O3AA 3KNUA 1J85A 1P9PA 4CNEB 1UAMA 1MXIA
chains in the KnotProt database with same CATH superfamily

#chains in the KnotProt database with same CATH superfamily
 3NK7 A;  3KTY A;  3AIA A;  1VHY A;  2I6D A;  3DCM X;  3N4J A;  3ILK A;  4IG6 A;  3ONP A;  1X7O A;  1UAJ A;  3N4K A;  3AXZ A;  3L8U A;  2QWV A;  3KW2 A;  4E8B A;  2CX8 A;  3E5Y A;  1NXZ A;  1ZJR A;  1TO0 A;  4H3Y A;  1VHK A;  1VH0 A;  1V6Z A;  4FAK A;  2Z0Y A;  1GZ0 A;  4CNG B;  3QUV A;  1K3R A;  3NK6 A;  1UAK A;  1UAL A;  3AI9 X;  3GYQ A;  3IC6 A;  4H3Z A;  2QMM A;  4CNF B;  1NS5 A;  1V2X A;  2HA8 A;  2YY8 A;  1O6D A;  3IEF A;  1X7P A;  3KY7 A;  2O3A A;  3KNU A;  1J85 A;  1P9P A;  4CNE B;  1UAM A;  1MXI A; 
#chains in the KnotProt database with same CATH topology
 3NK7 A;  3KTY A;  3AIA A;  1VHY A;  2I6D A;  3DCM X;  3N4J A;  3ILK A;  4IG6 A;  3ONP A;  1X7O A;  1UAJ A;  3N4K A;  3AXZ A;  3L8U A;  2QWV A;  3KW2 A;  4E8B A;  2CX8 A;  3E5Y A;  1NXZ A;  1ZJR A;  1TO0 A;  4H3Y A;  1VHK A;  1VH0 A;  1V6Z A;  4FAK A;  2Z0Y A;  1GZ0 A;  4CNG B;  3QUV A;  1K3R A;  3NK6 A;  1UAK A;  1UAL A;  3AI9 X;  3GYQ A;  3IC6 A;  4H3Z A;  2QMM A;  4CNF B;  1NS5 A;  1V2X A;  2HA8 A;  2YY8 A;  1O6D A;  3IEF A;  1X7P A;  3KY7 A;  2O3A A;  3KNU A;  1J85 A;  1P9P A;  4CNE B;  1UAM A;  1MXI A; 
#chains in the KnotProt database with same CATH homology
 3NK7 A;  3KTY A;  3AIA A;  1VHY A;  2I6D A;  3DCM X;  3N4J A;  3ILK A;  4IG6 A;  3ONP A;  1X7O A;  1UAJ A;  3N4K A;  3AXZ A;  3L8U A;  2QWV A;  3KW2 A;  4E8B A;  2CX8 A;  3E5Y A;  1NXZ A;  1ZJR A;  1TO0 A;  4H3Y A;  1VHK A;  1VH0 A;  1V6Z A;  4FAK A;  2Z0Y A;  1GZ0 A;  4CNG B;  3QUV A;  1K3R A;  3NK6 A;  1UAK A;  1UAL A;  3AI9 X;  3GYQ A;  3IC6 A;  4H3Z A;  2QMM A;  4CNF B;  1NS5 A;  1V2X A;  2HA8 A;  2YY8 A;  1O6D A;  3IEF A;  1X7P A;  3KY7 A;  2O3A A;  3KNU A;  1J85 A;  1P9P A;  4CNE B;  1UAM A;  1MXI A;

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similar chains in the KnotProt database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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2CX8A

Knot K +31

Chain Sequence

pfam database annotations

Knot K +3₁