4IG6A

Crystal structure of a trna (guanine-n1)-methyltransferase from anaplasma phagocytophilum bound to s-adenosylhomocysteine
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 86-130 45 1-85, 131-223 85 93 knot
Chain Sequence
SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 86-132 47 1-85, 133-223 85 91 knot
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2.1 84-128 45 1-83 134-223 129-133 83 90 slipknot
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2.1 88-157 70 1-85, 166-223 86-87, 158-165 85 58 slipknot
view details
2.1 88-169 82 1-85, 181-223 86-87, 170-180 85 43 slipknot
sequence length 223
structure length 223
publication title Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
rcsb
molecule tags Transferase/transferase inhibitor
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
source organism Anaplasma phagocytophilum
total genus Genus: 66
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-12-16
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ig6A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ig6A01
3IC6A 4FAKA 4IG6A 4CNEB 1TO0A 3KY7A 3AI9X 4CNFB 2HA8A 2QWVA 3L8UA 3GYQA 3NK7A 1NXZA 3NK6A 3N4KA 1P9PA 1MXIA 1UAJA 3QUVA 1X7PA 1UAMA 2I6DA 2QMMA 2O3AA 1GZ0A 2YY8A 1K3RA 3IEFA 3E5YA 4E8BA 1X7OA 3AXZA 1V2XA 1O6DA 4H3ZA 4CNGB 1UALA 3N4JA 4H3YA 3ILKA 1ZJRA 3KTYA 1VH0A 3KNUA 1V6ZA 2Z0YA 1VHKA 3DCMX 1VHYA 2CX8A 3AIAA 1J85A 1UAKA 3ONPA 1NS5A
chains in the KnotProt database with same CATH superfamily
3IC6A 4FAKA 4IG6A 4CNEB 1TO0A 3KY7A 3AI9X 4CNFB 2HA8A 2QWVA 3L8UA 3GYQA 3NK7A 1NXZA 3NK6A 3N4KA 1P9PA 1MXIA 1UAJA 3QUVA 1X7PA 1UAMA 2I6DA 2QMMA 2O3AA 1GZ0A 2YY8A 1K3RA 3IEFA 3E5YA 4E8BA 1X7OA 3AXZA 1V2XA 1O6DA 4H3ZA 4CNGB 1UALA 3N4JA 4H3YA 3ILKA 1ZJRA 3KTYA 1VH0A 3KNUA 1V6ZA 2Z0YA 1VHKA 3DCMX 1VHYA 2CX8A 3AIAA 1J85A 1UAKA 3ONPA 1NS5A
chains in the KnotProt database with same CATH topology
3IC6A 4FAKA 4IG6A 4CNEB 1TO0A 3KY7A 3AI9X 4CNFB 2HA8A 2QWVA 3L8UA 3GYQA 3NK7A 1NXZA 3NK6A 3N4KA 1P9PA 1MXIA 1UAJA 3QUVA 1X7PA 1UAMA 2I6DA 2QMMA 2O3AA 1GZ0A 2YY8A 1K3RA 3IEFA 3E5YA 4E8BA 1X7OA 3AXZA 1V2XA 1O6DA 4H3ZA 4CNGB 1UALA 3N4JA 4H3YA 3ILKA 1ZJRA 3KTYA 1VH0A 3KNUA 1V6ZA 2Z0YA 1VHKA 3DCMX 1VHYA 2CX8A 3AIAA 1J85A 1UAKA 3ONPA 1NS5A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3IC6 A;  4FAK A;  4IG6 A;  4CNE B;  1TO0 A;  3KY7 A;  3AI9 X;  4CNF B;  2HA8 A;  2QWV A;  3L8U A;  3GYQ A;  3NK7 A;  1NXZ A;  3NK6 A;  3N4K A;  1P9P A;  1MXI A;  1UAJ A;  3QUV A;  1X7P A;  1UAM A;  2I6D A;  2QMM A;  2O3A A;  1GZ0 A;  2YY8 A;  1K3R A;  3IEF A;  3E5Y A;  4E8B A;  1X7O A;  3AXZ A;  1V2X A;  1O6D A;  4H3Z A;  4CNG B;  1UAL A;  3N4J A;  4H3Y A;  3ILK A;  1ZJR A;  3KTY A;  1VH0 A;  3KNU A;  1V6Z A;  2Z0Y A;  1VHK A;  3DCM X;  1VHY A;  2CX8 A;  3AIA A;  1J85 A;  1UAK A;  3ONP A;  1NS5 A; 
#chains in the KnotProt database with same CATH topology
 3IC6 A;  4FAK A;  4IG6 A;  4CNE B;  1TO0 A;  3KY7 A;  3AI9 X;  4CNF B;  2HA8 A;  2QWV A;  3L8U A;  3GYQ A;  3NK7 A;  1NXZ A;  3NK6 A;  3N4K A;  1P9P A;  1MXI A;  1UAJ A;  3QUV A;  1X7P A;  1UAM A;  2I6D A;  2QMM A;  2O3A A;  1GZ0 A;  2YY8 A;  1K3R A;  3IEF A;  3E5Y A;  4E8B A;  1X7O A;  3AXZ A;  1V2X A;  1O6D A;  4H3Z A;  4CNG B;  1UAL A;  3N4J A;  4H3Y A;  3ILK A;  1ZJR A;  3KTY A;  1VH0 A;  3KNU A;  1V6Z A;  2Z0Y A;  1VHK A;  3DCM X;  1VHY A;  2CX8 A;  3AIA A;  1J85 A;  1UAK A;  3ONP A;  1NS5 A; 
#chains in the KnotProt database with same CATH homology
 3IC6 A;  4FAK A;  4IG6 A;  4CNE B;  1TO0 A;  3KY7 A;  3AI9 X;  4CNF B;  2HA8 A;  2QWV A;  3L8U A;  3GYQ A;  3NK7 A;  1NXZ A;  3NK6 A;  3N4K A;  1P9P A;  1MXI A;  1UAJ A;  3QUV A;  1X7P A;  1UAM A;  2I6D A;  2QMM A;  2O3A A;  1GZ0 A;  2YY8 A;  1K3R A;  3IEF A;  3E5Y A;  4E8B A;  1X7O A;  3AXZ A;  1V2X A;  1O6D A;  4H3Z A;  4CNG B;  1UAL A;  3N4J A;  4H3Y A;  3ILK A;  1ZJR A;  3KTY A;  1VH0 A;  3KNU A;  1V6Z A;  2Z0Y A;  1VHK A;  3DCM X;  1VHY A;  2CX8 A;  3AIA A;  1J85 A;  1UAK A;  3ONP A;  1NS5 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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