4FAKA

Crystal structure of orfx in complex with s-adenosylmethionine
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 79-128 50 1-78, 129-163 78 35 knot
Chain Sequence
AAEFMKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 78-129 52 1-77, 130-163 77 34 knot
view details
2.1 80-154 75 1-77, 161-163 78-79, 155-160 77 3 slipknot
view details
3.1 80-160 81 1-77, 163-163 78-79, 161-162 77 1 slipknot
sequence length 163
structure length 163
publication title Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site.
pubmed doi rcsb
molecule tags Transferase, ribosomal protein
molecule keywords Ribosomal RNA large subunit methyltransferase H
source organism Staphylococcus aureus
total genus Genus: 53
ec nomenclature ec 2.1.1.177: 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
pdb deposition date 2012-05-22
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02590 SPOUT_MTase Predicted SPOUT methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4fakA00
3NK7A 1J85A 4FAKA 3KNUA 4CNFB 1TO0A 2HA8A 1K3RA 2QWVA 1VH0A 2CX8A 3L8UA 4CNEB 1UAKA 1UAMA 2O3AA 2I6DA 3E5YA 1V2XA 2YY8A 3N4KA 1X7PA 3AXZA 3NK6A 4IG6A 4H3YA 4H3ZA 1V6ZA 1UALA 1X7OA 3IC6A 3ONPA 2QMMA 3QUVA 3GYQA 1NS5A 3KY7A 1O6DA 4E8BA 1GZ0A 3IEFA 1ZJRA 1P9PA 1UAJA 3DCMX 2Z0YA 3KTYA 1VHYA 3N4JA 3AI9X 3ILKA 4CNGB 1VHKA 1MXIA 1NXZA 3AIAA
chains in the KnotProt database with same CATH superfamily
3NK7A 1J85A 4FAKA 3KNUA 4CNFB 1TO0A 2HA8A 1K3RA 2QWVA 1VH0A 2CX8A 3L8UA 4CNEB 1UAKA 1UAMA 2O3AA 2I6DA 3E5YA 1V2XA 2YY8A 3N4KA 1X7PA 3AXZA 3NK6A 4IG6A 4H3YA 4H3ZA 1V6ZA 1UALA 1X7OA 3IC6A 3ONPA 2QMMA 3QUVA 3GYQA 1NS5A 3KY7A 1O6DA 4E8BA 1GZ0A 3IEFA 1ZJRA 1P9PA 1UAJA 3DCMX 2Z0YA 3KTYA 1VHYA 3N4JA 3AI9X 3ILKA 4CNGB 1VHKA 1MXIA 1NXZA 3AIAA
chains in the KnotProt database with same CATH topology
3NK7A 1J85A 4FAKA 3KNUA 4CNFB 1TO0A 2HA8A 1K3RA 2QWVA 1VH0A 2CX8A 3L8UA 4CNEB 1UAKA 1UAMA 2O3AA 2I6DA 3E5YA 1V2XA 2YY8A 3N4KA 1X7PA 3AXZA 3NK6A 4IG6A 4H3YA 4H3ZA 1V6ZA 1UALA 1X7OA 3IC6A 3ONPA 2QMMA 3QUVA 3GYQA 1NS5A 3KY7A 1O6DA 4E8BA 1GZ0A 3IEFA 1ZJRA 1P9PA 1UAJA 3DCMX 2Z0YA 3KTYA 1VHYA 3N4JA 3AI9X 3ILKA 4CNGB 1VHKA 1MXIA 1NXZA 3AIAA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3NK7 A;  1J85 A;  4FAK A;  3KNU A;  4CNF B;  1TO0 A;  2HA8 A;  1K3R A;  2QWV A;  1VH0 A;  2CX8 A;  3L8U A;  4CNE B;  1UAK A;  1UAM A;  2O3A A;  2I6D A;  3E5Y A;  1V2X A;  2YY8 A;  3N4K A;  1X7P A;  3AXZ A;  3NK6 A;  4IG6 A;  4H3Y A;  4H3Z A;  1V6Z A;  1UAL A;  1X7O A;  3IC6 A;  3ONP A;  2QMM A;  3QUV A;  3GYQ A;  1NS5 A;  3KY7 A;  1O6D A;  4E8B A;  1GZ0 A;  3IEF A;  1ZJR A;  1P9P A;  1UAJ A;  3DCM X;  2Z0Y A;  3KTY A;  1VHY A;  3N4J A;  3AI9 X;  3ILK A;  4CNG B;  1VHK A;  1MXI A;  1NXZ A;  3AIA A; 
#chains in the KnotProt database with same CATH topology
 3NK7 A;  1J85 A;  4FAK A;  3KNU A;  4CNF B;  1TO0 A;  2HA8 A;  1K3R A;  2QWV A;  1VH0 A;  2CX8 A;  3L8U A;  4CNE B;  1UAK A;  1UAM A;  2O3A A;  2I6D A;  3E5Y A;  1V2X A;  2YY8 A;  3N4K A;  1X7P A;  3AXZ A;  3NK6 A;  4IG6 A;  4H3Y A;  4H3Z A;  1V6Z A;  1UAL A;  1X7O A;  3IC6 A;  3ONP A;  2QMM A;  3QUV A;  3GYQ A;  1NS5 A;  3KY7 A;  1O6D A;  4E8B A;  1GZ0 A;  3IEF A;  1ZJR A;  1P9P A;  1UAJ A;  3DCM X;  2Z0Y A;  3KTY A;  1VHY A;  3N4J A;  3AI9 X;  3ILK A;  4CNG B;  1VHK A;  1MXI A;  1NXZ A;  3AIA A; 
#chains in the KnotProt database with same CATH homology
 3NK7 A;  1J85 A;  4FAK A;  3KNU A;  4CNF B;  1TO0 A;  2HA8 A;  1K3R A;  2QWV A;  1VH0 A;  2CX8 A;  3L8U A;  4CNE B;  1UAK A;  1UAM A;  2O3A A;  2I6D A;  3E5Y A;  1V2X A;  2YY8 A;  3N4K A;  1X7P A;  3AXZ A;  3NK6 A;  4IG6 A;  4H3Y A;  4H3Z A;  1V6Z A;  1UAL A;  1X7O A;  3IC6 A;  3ONP A;  2QMM A;  3QUV A;  3GYQ A;  1NS5 A;  3KY7 A;  1O6D A;  4E8B A;  1GZ0 A;  3IEF A;  1ZJR A;  1P9P A;  1UAJ A;  3DCM X;  2Z0Y A;  3KTY A;  1VHY A;  3N4J A;  3AI9 X;  3ILK A;  4CNG B;  1VHK A;  1MXI A;  1NXZ A;  3AIA A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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