2HA8A

Methyltransferase domain of human tar (hiv-1) rna binding protein 1
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 86-127 42 1-85, 128-159 85 32 knot
Chain Sequence
LGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLS
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 86-128 43 1-85, 129-159 85 31 knot
view details
2.1 85-125 41 1-84 131-159 126-130 84 29 slipknot
view details
3.1 88-147 60 148-159 1-85 86-87 85 11 slipknot
sequence length 159
structure length 159
publication title The Crystal Structure of Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1 in complex with S-adenosyl-L-homocystein.
rcsb
molecule tags Rna binding protein
molecule keywords TAR (HIV-1) RNA loop binding protein
source organism Homo sapiens
total genus Genus: 57
ec nomenclature
pdb deposition date 2006-06-12
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2ha8A01
1VHYA 1UAJA 4H3ZA 2QMMA 4CNEB 1X7PA 1O6DA 3KNUA 3N4KA 4E8BA 3AI9X 4FAKA 1NS5A 3IC6A 1UAMA 1TO0A 4IG6A 1J85A 2QWVA 3GYQA 1UAKA 1K3RA 1GZ0A 1VH0A 1ZJRA 1MXIA 3AIAA 3NK7A 3KY7A 3KTYA 3AXZA 1UALA 2HA8A 3ONPA 1NXZA 2I6DA 4H3YA 3ILKA 4CNFB 4CNGB 1P9PA 1V6ZA 1X7OA 2CX8A 3DCMX 3E5YA 1VHKA 2O3AA 3IEFA 3QUVA 2Z0YA 3NK6A 3N4JA 3L8UA 2YY8A 1V2XA
chains in the KnotProt database with same CATH superfamily
1VHYA 1UAJA 4H3ZA 2QMMA 4CNEB 1X7PA 1O6DA 3KNUA 3N4KA 4E8BA 3AI9X 4FAKA 1NS5A 3IC6A 1UAMA 1TO0A 4IG6A 1J85A 2QWVA 3GYQA 1UAKA 1K3RA 1GZ0A 1VH0A 1ZJRA 1MXIA 3AIAA 3NK7A 3KY7A 3KTYA 3AXZA 1UALA 2HA8A 3ONPA 1NXZA 2I6DA 4H3YA 3ILKA 4CNFB 4CNGB 1P9PA 1V6ZA 1X7OA 2CX8A 3DCMX 3E5YA 1VHKA 2O3AA 3IEFA 3QUVA 2Z0YA 3NK6A 3N4JA 3L8UA 2YY8A 1V2XA
chains in the KnotProt database with same CATH topology
1VHYA 1UAJA 4H3ZA 2QMMA 4CNEB 1X7PA 1O6DA 3KNUA 3N4KA 4E8BA 3AI9X 4FAKA 1NS5A 3IC6A 1UAMA 1TO0A 4IG6A 1J85A 2QWVA 3GYQA 1UAKA 1K3RA 1GZ0A 1VH0A 1ZJRA 1MXIA 3AIAA 3NK7A 3KY7A 3KTYA 3AXZA 1UALA 2HA8A 3ONPA 1NXZA 2I6DA 4H3YA 3ILKA 4CNFB 4CNGB 1P9PA 1V6ZA 1X7OA 2CX8A 3DCMX 3E5YA 1VHKA 2O3AA 3IEFA 3QUVA 2Z0YA 3NK6A 3N4JA 3L8UA 2YY8A 1V2XA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1VHY A;  1UAJ A;  4H3Z A;  2QMM A;  4CNE B;  1X7P A;  1O6D A;  3KNU A;  3N4K A;  4E8B A;  3AI9 X;  4FAK A;  1NS5 A;  3IC6 A;  1UAM A;  1TO0 A;  4IG6 A;  1J85 A;  2QWV A;  3GYQ A;  1UAK A;  1K3R A;  1GZ0 A;  1VH0 A;  1ZJR A;  1MXI A;  3AIA A;  3NK7 A;  3KY7 A;  3KTY A;  3AXZ A;  1UAL A;  2HA8 A;  3ONP A;  1NXZ A;  2I6D A;  4H3Y A;  3ILK A;  4CNF B;  4CNG B;  1P9P A;  1V6Z A;  1X7O A;  2CX8 A;  3DCM X;  3E5Y A;  1VHK A;  2O3A A;  3IEF A;  3QUV A;  2Z0Y A;  3NK6 A;  3N4J A;  3L8U A;  2YY8 A;  1V2X A; 
#chains in the KnotProt database with same CATH topology
 1VHY A;  1UAJ A;  4H3Z A;  2QMM A;  4CNE B;  1X7P A;  1O6D A;  3KNU A;  3N4K A;  4E8B A;  3AI9 X;  4FAK A;  1NS5 A;  3IC6 A;  1UAM A;  1TO0 A;  4IG6 A;  1J85 A;  2QWV A;  3GYQ A;  1UAK A;  1K3R A;  1GZ0 A;  1VH0 A;  1ZJR A;  1MXI A;  3AIA A;  3NK7 A;  3KY7 A;  3KTY A;  3AXZ A;  1UAL A;  2HA8 A;  3ONP A;  1NXZ A;  2I6D A;  4H3Y A;  3ILK A;  4CNF B;  4CNG B;  1P9P A;  1V6Z A;  1X7O A;  2CX8 A;  3DCM X;  3E5Y A;  1VHK A;  2O3A A;  3IEF A;  3QUV A;  2Z0Y A;  3NK6 A;  3N4J A;  3L8U A;  2YY8 A;  1V2X A; 
#chains in the KnotProt database with same CATH homology
 1VHY A;  1UAJ A;  4H3Z A;  2QMM A;  4CNE B;  1X7P A;  1O6D A;  3KNU A;  3N4K A;  4E8B A;  3AI9 X;  4FAK A;  1NS5 A;  3IC6 A;  1UAM A;  1TO0 A;  4IG6 A;  1J85 A;  2QWV A;  3GYQ A;  1UAK A;  1K3R A;  1GZ0 A;  1VH0 A;  1ZJR A;  1MXI A;  3AIA A;  3NK7 A;  3KY7 A;  3KTY A;  3AXZ A;  1UAL A;  2HA8 A;  3ONP A;  1NXZ A;  2I6D A;  4H3Y A;  3ILK A;  4CNF B;  4CNG B;  1P9P A;  1V6Z A;  1X7O A;  2CX8 A;  3DCM X;  3E5Y A;  1VHK A;  2O3A A;  3IEF A;  3QUV A;  2Z0Y A;  3NK6 A;  3N4J A;  3L8U A;  2YY8 A;  1V2X A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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