2HA8A

Methyltransferase domain of human tar (hiv-1) rna binding protein 1
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 86-127 42 1-85, 128-159 85 32 knot
Chain Sequence
LGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLS
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 86-128 43 1-85, 129-159 85 31 knot
view details
2.1 85-125 41 1-84 131-159 126-130 84 29 slipknot
view details
3.1 88-147 60 148-159 1-85 86-87 85 11 slipknot
publication title The Crystal Structure of Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1 in complex with S-adenosyl-L-homocystein.
rcsb
structure length 159
molecule tags Rna binding protein
source organism Homo sapiens
sequence length 159
total genus Genus: 57
molecule keywords TAR (HIV-1) RNA loop binding protein
ec nomenclature
pdb deposition date 2006-06-12
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2ha8A01
3KTYA 1K3RA 3E5YA 1VHKA 1UALA 1GZ0A 3IEFA 3AI9X 3KNUA 1UAJA 1ZJRA 3NK6A 2QMMA 2HA8A 3KY7A 1X7OA 1J85A 1NS5A 3IC6A 3NK7A 3ONPA 3AXZA 3GYQA 1NXZA 2Z0YA 3L8UA 4E8BA 3ILKA 3DCMX 3N4KA 4IG6A 1VHYA 2CX8A 3N4JA 3AIAA 1MXIA 4H3ZA 2I6DA 1X7PA 2O3AA 1P9PA 2YY8A 3QUVA 1V6ZA 4FAKA 1TO0A 1O6DA 2QWVA 1V2XA 1UAMA 4H3YA 1VH0A 1IPAA 1UAKA
chains in the KnotProt database with same CATH superfamily
3KTYA 1K3RA 3E5YA 1VHKA 1UALA 1GZ0A 3IEFA 3AI9X 3KNUA 1UAJA 1ZJRA 3NK6A 2QMMA 2HA8A 3KY7A 1X7OA 1J85A 1NS5A 3IC6A 3NK7A 3ONPA 3AXZA 3GYQA 1NXZA 2Z0YA 3L8UA 4E8BA 3ILKA 3DCMX 3N4KA 4IG6A 1VHYA 2CX8A 3N4JA 3AIAA 1MXIA 4H3ZA 2I6DA 1X7PA 2O3AA 1P9PA 2YY8A 3QUVA 1V6ZA 4FAKA 1TO0A 1O6DA 2QWVA 1V2XA 1UAMA 4H3YA 1VH0A 1IPAA 1UAKA
chains in the KnotProt database with same CATH topology
3KTYA 1K3RA 3E5YA 1VHKA 1UALA 1GZ0A 3IEFA 3AI9X 3KNUA 1UAJA 1ZJRA 3NK6A 2QMMA 2HA8A 3KY7A 1X7OA 1J85A 1NS5A 3IC6A 3NK7A 3ONPA 3AXZA 3GYQA 1NXZA 2Z0YA 3L8UA 4E8BA 3ILKA 3DCMX 3N4KA 4IG6A 1VHYA 2CX8A 3N4JA 3AIAA 1MXIA 4H3ZA 2I6DA 1X7PA 2O3AA 1P9PA 2YY8A 3QUVA 1V6ZA 4FAKA 1TO0A 1O6DA 2QWVA 1V2XA 1UAMA 4H3YA 1VH0A 1IPAA 1UAKA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3KTY A;  1K3R A;  3E5Y A;  1VHK A;  1UAL A;  1GZ0 A;  3IEF A;  3AI9 X;  3KNU A;  1UAJ A;  1ZJR A;  3NK6 A;  2QMM A;  2HA8 A;  3KY7 A;  1X7O A;  1J85 A;  1NS5 A;  3IC6 A;  3NK7 A;  3ONP A;  3AXZ A;  3GYQ A;  1NXZ A;  2Z0Y A;  3L8U A;  4E8B A;  3ILK A;  3DCM X;  3N4K A;  4IG6 A;  1VHY A;  2CX8 A;  3N4J A;  3AIA A;  1MXI A;  4H3Z A;  2I6D A;  1X7P A;  2O3A A;  1P9P A;  2YY8 A;  3QUV A;  1V6Z A;  4FAK A;  1TO0 A;  1O6D A;  2QWV A;  1V2X A;  1UAM A;  4H3Y A;  1VH0 A;  1IPA A;  1UAK A; 
#chains in the KnotProt database with same CATH topology
 3KTY A;  1K3R A;  3E5Y A;  1VHK A;  1UAL A;  1GZ0 A;  3IEF A;  3AI9 X;  3KNU A;  1UAJ A;  1ZJR A;  3NK6 A;  2QMM A;  2HA8 A;  3KY7 A;  1X7O A;  1J85 A;  1NS5 A;  3IC6 A;  3NK7 A;  3ONP A;  3AXZ A;  3GYQ A;  1NXZ A;  2Z0Y A;  3L8U A;  4E8B A;  3ILK A;  3DCM X;  3N4K A;  4IG6 A;  1VHY A;  2CX8 A;  3N4J A;  3AIA A;  1MXI A;  4H3Z A;  2I6D A;  1X7P A;  2O3A A;  1P9P A;  2YY8 A;  3QUV A;  1V6Z A;  4FAK A;  1TO0 A;  1O6D A;  2QWV A;  1V2X A;  1UAM A;  4H3Y A;  1VH0 A;  1IPA A;  1UAK A; 
#chains in the KnotProt database with same CATH homology
 3KTY A;  1K3R A;  3E5Y A;  1VHK A;  1UAL A;  1GZ0 A;  3IEF A;  3AI9 X;  3KNU A;  1UAJ A;  1ZJR A;  3NK6 A;  2QMM A;  2HA8 A;  3KY7 A;  1X7O A;  1J85 A;  1NS5 A;  3IC6 A;  3NK7 A;  3ONP A;  3AXZ A;  3GYQ A;  1NXZ A;  2Z0Y A;  3L8U A;  4E8B A;  3ILK A;  3DCM X;  3N4K A;  4IG6 A;  1VHY A;  2CX8 A;  3N4J A;  3AIA A;  1MXI A;  4H3Z A;  2I6D A;  1X7P A;  2O3A A;  1P9P A;  2YY8 A;  3QUV A;  1V6Z A;  4FAK A;  1TO0 A;  1O6D A;  2QWV A;  1V2X A;  1UAM A;  4H3Y A;  1VH0 A;  1IPA A;  1UAK A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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